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1 Vial
Rituximab
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Overview
Maball 500mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, and blood cancer (chronic lymphocytic leukemia). It is an injection given under the supervision of a qualified healthcare provider. The active ingredient of Maball injection is Rituximab. It is available in a strength of 500 mg. It is a genetically engineered chimeric murine/human monoclonal antibody, which is directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes.
Blood Cancer
Non-Hodgkin lymphoma (NHL)
Blood cancer (Chronic lymphocytic leukemia)
Rheumatoid arthritis
Granulomatosis with polyangiitis
Microscopic polyangiitis
Maball 500mg Injection may cause certain side effects. If side effects occur after administration or last longer than usual, contact your healthcare professional.
Headache
Cough Fever and Chills Hair loss
Decrease in WBC, RBC, and Platelets
Skin rash Insomnia
Sore throat
Maball 500mg Injection is given under the supervision of a professional healthcare provider. Make sure to have a word with your healthcare provider regarding your medical condition and medical history. Also, give access to the list of medicines you already take. Seek immediate medical help in case of overdose.
Maball 500mg Injection links to the CD20 antigen on normal and malignant B-cells. Therefore, the essential immune system of the body is initiated to attack and then kill the marked B-cells. Stem cells in the bone marrow grow into various cell types. They do not have the CD20 antigen. After the treatment, the CD20 antigen allows the multiplication of healthy B-cells.
Alcohol
unsafe
It is advisable not to consume alcohol while taking this medicine.
Pregnancy
consult your doctor
Do not take Maball 500mg Injection without consulting the doctor, in case of pregnancy.
Breast Feeding
consult your doctor
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
Driving
warning
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
caution
Do not take Maball Injection without a doctor's consultation in case of kidney problems.
Liver
caution
Share your medical history with the doctor in case of liver disease before taking this medicine.
In case you miss a dose, make sure to consult your healthcare provider to get proper guidance. Do not double the dose for compensation.
Maball 500mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, and blood cancer (chronic lymphocytic leukemia). It is an injection given under the supervision of a qualified healthcare provider.
The side effects of Maball injection are fever, weakness, headache, chills, insomnia, skin rash, and itching. It is advised to contact your healthcare provider regarding the side effects you experience while consuming this medicine. Also, note that there can be other side effects also.
Alcohol may worsen the condition. Make sure to take advice from a healthcare provider before consuming alcohol with this medicine.
Maball 500mg Injection may be unsafe for use during pregnancy or while breastfeeding. Make sure to consult your healthcare provider.
If you feel dizzy after taking Maball, make sure to avoid driving or operating heavy machines.
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Feder, O., Amsterdam, D., Ershed, M., et al. (2025). Long‑term efficacy of rituximab in steroid‑dependent and frequent relapsing adult nephrotic syndrome. BMC Nephrology, 26, 126.
Kalenik, V. A., Belada, D., Oliveira, A. C., et al. (2024). Efficacy and safety of rituximab biosimilar (DRL_RI) versus MabThera® in low-tumor-burden follicular lymphoma: The FLINTER study. Blood, 144 (Supplement 1), 6276
Kimby, E. K., Schär, S., Pirosa, M. C., et al. (2025). Six‑month rituximab‑lenalidomide regimen in advanced untreated follicular lymphoma: SAKK 35/10 trial 10‑year update. Blood Advances.
Maharaj, N., Uppada, D. R., Reddy, N., et al. (2024). Comparing immunogenicity and safety following transition from reference rituximab to biosimilar rituximab (DRL_RI) in patients with rheumatoid arthritis: A randomized, double‑blind, phase 3 study. Arthritis Research & Therapy, 26, 225.
Zheng, X., Di, J., Chen, X., Li, F., Liu, Y., Cao, J., Ning, X., Wei, L., & Zheng, G. (2025). Meta-analysis of the efficacy and safety of rituximab in the treatment of primary Sjögren’s syndrome. Frontiers in Immunology, 16, 1561214.
Hetero
Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.