Mfd. by :- Bristol-myers Squibb pharma (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand name :- Opdivo
Generic name :- Nivolumab
Manufacturer :- Bristol-myers Squibb pharma
Dosage form :- Injection
Strength :- 40mg/4ml
Composition :- Nivolumab
Packaging size :- 1 vial
Indication:- Head and neck cancer, kidney cancer, lung cancer, liver cancer, skin cancer.
Storage conditions:- Store in a cool and dry place.
Opdivo (Nivolumab 100mg) is a prescription medicine used to treat people with certain cancers (lung cancer, liver cancer, skin cancer, head and neck cancer). This medication is also used to treat people with a type of advanced-stage lung cancer that has spread or grown and you have tried chemotherapy and it did not work.
A dose ranges from 0.1mg to 20mg administered as a single dose or multiple doses of opdivo (nivolumab) as a 60 minutes intravenous infusion every 2 to 3 weeks. The predicted exposure of opdivo after a 30 minutes infusion is comparable to 60 minutes infusion.
It is indicated for metastatic small cell lung cancer in patients with progression after platinum-based chemotherapy.
Indicated for patients with poor-risk, previously untreated advanced renal cell carcinoma.
Indicated for melanoma in patients with lymph node involvement.
The use of this drug may cause some unwanted effects.
Shortness of breath
Low amount of sodium in the blood
Note:- immediately contact your doctor if any of these side effects occur.
Bleeding from lungs
A facial nerve disorder
Lung tissue problem
High blood pressure
Stomatitis, a condition with painful swelling and sores inside the mouth.
Blurry vision or double vision
Eye pain or redness
Opdivo (Nivolumab 100mg) medicine is used to treat people with a type of skin cancer called melanoma that has spread or cannot be removed by surgery. It is also used when your head and neck, bladder, small- cell lung cancer has come back or spread and you have tried chemotherapy that contains platinum and it did not work or no longer is working.
Immune-mediated adverse reactions ( diarrhea, pneumonitis, renal dysfunction) which may be severe, can occur in any organ system or tissue.
Monitor for signs and symptoms of adrenal insufficiency during and after treatment.
Severe infusion-related reactions can occur.
May cause harm when administered to pregnant females.
When used in combination with ipilimumab, refer to prescribing information for additional risk information that applies to the combination use treatment.
May cause type 1 diabetes.
May harm the immune system
Do not drive after taking this medication
Not safe for pregnant women
Do not take this medication without a doctor advice
Ans. Opdivo is a cancer medicine that is used for the treatment of numerous types of cancers like radical skin cancer, lung cancer, kidney cancer, classical Hodgkin lymphoma, squamous cell cancer of the head and neck, bladder cancer, and liver cancer.
Ans. Opdivo injection is used in the following conditions:-
Melanoma:- patients with melanoma that can’t be removed by surgery as a single agent.
Non-small cell lung cancer:- patients with non-small cell lung cancer who have progressed on or after treatment with platinum-based chemotherapy.
Ans. This medication is given as an intravenous infusion by your doctor or nurse. The dose and schedule vary by approved indication.
Ans Opdivo works with your immune system to attack cancer, but it can also cause your immune system to attack normal organs and tissues. Your doctor will monitor with certain blood tests.
Ans Common side effects are;- Nausea, Skin rash, Fatigue, Constipation, Diarrhea, Vomiting, Cough, Muscle pain, Decreased appetite, Shortness of breath, Fever, Swelling, Joint pain, Chest pain, Headache, etc.
Ans. If you have symptoms of shortness of breath, chest pain, kidney problem and other signs of a problem with other organs like:- rash, change in eyesight, severe muscle weakness.
Ans It is available in the strength of 40mg/4ml.
Ans. Immediately contact your doctor in case you miss any dose of opdivo injection.
Ans. Consult your doctor and follow their instructions on your food and beverage activity.
Ans. Patients should tell their medical history to the doctor and particularly if you’ve:- immune system problem, lung or breathing problems, or if you had an organ transplant.
Ans. This medication is not recommended for pregnant women, because it may harm the unborn baby.
Ans It is unsafe during breastfeeding, that’s why it is not recommended for breastfeeding women
Ans. Regular monitoring of kidney function tests is required while you are taking this medicine. Please consult your doctor before taking the dosage.
Ans. it is important if you keep a list of all the prescription medicine you are taking. It is also important information to carry with you in case of emergencies.