OXALTERO

Mfd. by :- Hetero (Fulfilled By : Magicine Pharma)

Oxaltero

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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PACKAGE

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Brand name:- Oxaltero 

Generic name:- Oxaliplatin

Manufacturer:- Hetero

Dosage form:- Injection

Strength:- 100mg

Composition:- Oxaliplatin

Packaging:- 1 vial

Indication:- Colorectal cancer

Storage:- Store at room temperature

Overview

Oxaltero (Oxaliplatin) injection is used in the treatment of colorectal cancer. This infusion works by killing cancerous cells and slows the growth of tumors. This medicine is given in the form of an injection by a doctor or nurse. Take this medicine as prescribed by your medical advisor. Your doctor will decide the exact dosage. Take this medicine according to your doctor’s dosing schedule. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change or stop the dose without taking suggestions from your doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately.  

Pharmacodynamics of Oxaltero (Oxaliplatin)

Oxaliplatin selectively inhibits the synthesis of DNA. Oxaliplatin undergoes nonenzymatic conversion in physiologic solutions to active derivatives via displacement of the labile oxalate ligand. The effect of this medicine can be observed in 2 hours after the intravenous infusion.

Side effects of Oxaltero (Oxaliplatin)

This medicine may cause some serious and unwanted side effects. It requires immediate medical attention otherwise it can also lead to higher risk. Discuss the risks and benefits of this medication with your medical advisor before starting the treatment. 

Common side effects 

  • Nausea 

  • Anemia 

  • Fatigue 

  • Vomiting 

  • Fever 

  • Loss of appetite 

  • Skin rash 

  • Low white blood cells 

  • Diarrhea 

  • Stomatitis 

  • Increased liver enzymes 

  • Low blood platelets 

  • Bleeding gums 

  • Chest pain 

  • Cough 

  • Dizziness 

  • Sore throat

  • Irregular heartbeat 

  • Acidic stomach 

  • Shortness of breath 

  • Mouth ulcers 

  • Swelling of eyelids, face. 

  • Joint pain 

  • Pale skin 

  • Change in taste 

  • Runny nose 

  • Constipation 

  • Headache 

  • Pale skin 

  • Numbness 

  • Lightheadedness 

  • Muscle pain 

  • Allergic reaction 

  • Difficulty in swallowing 

  • Bone pain 

  • Indigestion 

Note- Immediate medical attention is required if any side effects occur.

Dosage

Take this injection as prescribed by your doctor. Do not self administer.  The injection is given as an infusion into your vein by a doctor or nurse. 

Missed dose 

  •  It is advisable not to miss a dose. If you miss an appointment for a scheduled dose of this medicine, contact your doctor immediately. 

Overdose 

  • In case of an overdose, the doctor will provide emergency medical treatment.

Usage of Oxaltero (Oxaliplatin)

This medicine is used in the treatment of cancer that affects the large intestine of the digestive system. It stops the growth of cancer cells and also prevents the multiplication of cancerous cells. The use of this injection is not recommended in pregnant women and children. The recommended dose of this medicine is decided by your doctor according to your medical condition and response to the treatment. Oxaliplatin is a chemotherapy drug that contains platinum. This medicine is also used with other medications to treat cancer. This medicine may decrease your blood count. 

Warnings

Before starting treatment with Oxaltero, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk. 

  •  Contraception 

    • Use effective methods of contraception to prevent pregnancy while taking this medicine. 

  • Children and adolescents 

    • This medicine is not advisable for use in children and adolescents. 

Warnings for female 

  • Pregnancy 

    • Oxaltero shouldn’t be used by pregnant women. Oxaliplatin may cause harm to the baby. It is recommended that this medicine should be avoided during pregnancy. 

 

  • Breastfeeding 

    • This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication.

General warning and precautions 

  • This medicine may cause severe kidney injury. 

  • Close monitoring of blood cell count is required. 

  • This medicine may cause hearing problems. 

  • Tingling or burning sensation of hands and feet should be reported to the doctor. Because it may cause some severe nerve damage. 

  • This medication may cause lung and liver injury. 

  • It may cause some serious skin reactions. 

  • Avoid contact with people who have infections. 

Cautions

  • Not safe for pregnant women. 

  • Do not drive or operate heavy machinery. 

  • May harm the liver. 

  • Do not self administer this medicine.

  • Do not breastfeed while receiving this medication.

Q1. What is Oxaltero (Oxaliplatin)? 

Ans. Oxaltero (Oxaliplatin) injection is used in the treatment of colorectal cancer. It stops the growth of cancer cells and also prevents the multiplication of cancerous cells. 

Q2. How does Oxaltero injection work? 

Ans. This is an anti-cancer medication. This infusion works by killing cancerous cells and slows the growth of tumors. 

Q3. What are the side effects? 

Ans. Some common side effects are:- Vomiting, anemia, blurred vision, skin rash, low white blood cells, nausea, chest pain, diarrhea, etc.

Q4. What should I avoid while receiving this medicine? 

Ans.  Avoid cold temperatures and cold objects. This medicine may cause dizziness, avoid driving. 

Q5. How long does it take this medicine to show effects?

Ans. The effect of this medicine can be observed in 2 hours after the dose administration. 

Q6. What happens if I miss a dose? 

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q7. In what strength is it available? 

Ans. It is available in the strength of 100mg.

Q8. Can I consume alcohol while taking this medicine? 

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q9. Does this affect liver function? 

Ans. Use of Oxaltero injection is not recommended in patients with severe liver disease. 

Q10. Can I drive after taking this medicine? 

Ans. This medicine may decrease your ability to drive or affect your vision. Do not drive if any symptoms occur. 

Q11. Does this affect kidney function? 

Ans. Please consult your doctor, before consuming this drug. 

Q12. Can I take this medicine during pregnancy?

Ans. This medicine is not recommended for pregnant women. 

Q13. Can I take this medicine during breastfeeding? 

Ans.  This medicine is not recommended in breastfeeding unless it is necessary.

Q14. What are the storage conditions? 

Ans. Store this medicine at room temperature. Do not shake or freeze the medicine.

Interactions

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor. 

Medicine interaction 

  • Atorvastatin 

  • Baricitinib 

  • Clozapine 

  • Chloroquine 

  • Etanercept 

  • Nilotinib 

  • Vancomycin 

Disease interaction 

  • Renal impairment 

  • Lung injuries 

  • Arrhythmias 

  • Neutropenia 

  • Thrombocytopenia 

Alcohol interaction 

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol. 

Contraindication 

  • Not recommended in patients with low white blood cell and platelet count 

  • Oxaltero injection is not recommended for use in patients with a known allergy to Oxaliplatin.  

  • This medicine is contracted in patients known to be hypersensitive.

 

Above Content has been reviewed by Professionals