Marketed By
dr. reddys laboratories ltd
Pack of
1 Injection
Salt Composition
Denosumab
Storage
Keep in cold place
Delivering To: —
All Substitutes
Overview
Prolia 60mg Injection is used in the treatment of osteoporosis (bone loss) in patients who have a very high risk of bone fracture. Osteoporosis mostly happens in women after menopause, making it more likely to break easily.
This medicine maintains bone density by slowing down bone loss and decreasing the risk of bone fractures. It belongs to the monoclonal antibodies class. It can also be used by males.
Indication
- Postmenopausal Osteoporosis
- Male Osteoporosis
- Steroid-Induced Bone Loss
- Bone Loss in Men/Women on Cancer Therapy
Uses
- Postmenopausal Osteoporosis
- Male Osteoporosis
- Steroid-Induced Bone Loss
- Bone Loss in Men/Women on Cancer Therapy
Side Effects
The human body reacts differently to Prolia 60mg Injection. Response or undesired symptoms vary from individual to individual. Usually, they disappear with time as the body adjusts to the medicine; these side effects don't need special medical attention. Whereas if the symptoms don't disappear with time or you have severe side effects, then consult your doctor immediately. Some of the common side effects of Prolia 60mg Injection are mentioned below:
- Rash
- Sciatica
- Musculoskeletal (bone, muscle, or joint) pain
- Infection in the upper respiratory tract
- Hair loss
- Headache
- Nerve pain
- Constipation
- Eczema
- Urinary tract infection
- Hypercholesterolemia (high cholesterol)
- Cystitis
- Fatigue
- Hypocalcemia
How To Use
- The Prolia 60mg injection is injected in your upper thigh, stomach, or upper arm. Normally, you get it every 6 months.
- For more information, talk to your doctor. This injection should not be self-administered and should be given by a health care professional.
- To make it more effective, take a balanced diet and take an adequate amount of Vitamin D and calcium while on treatment with Prolia 60mg injection.
How It Works
The Prolia 60mg injection is a monoclonal antibody. It prevents bones from getting fractures or reduces the risk of bone loss by binding to a protein that weakens the bone. As a result, bones get strengthened, and the risk of fractures is minimized.
Safety Advice
Alcohol
UNSAFE
Pregnancy
CONSULT YOUR DOCTOR
Breast Feeding
CONSULT YOUR DOCTOR
Driving
DANGER
Kidney
CAUTION
Liver
CAUTION
Missed Doses
It is advisable not to miss any dose. In case you miss a dose of Prolia 60mg Injection consult your doctor soon.
Missing the dose will impact the overall health of the patients. So, it is always advisable to follow the prescription of the doctor strictly.
FAQs
Prolia 60mg injection increases the bone density accordingly cancer cells.
The duration of treatment will depend on the stage of cancer and the overall health of patients.
Driving and operating heavy machinery is advisable because this injection makes you feel dizzy.
Pregnant women should consult a doctor before taking Prolia injection.
Yes, Prolia 60mg can cause hair loss, which is a common side effect of this medication. Consult your doctor if you are concerned about your hair loss.
Prolia 60mg injection can be stored in a refrigerator at 2 to 8 degrees Celsius in the sealed container without breaking it. Keeping the injection at a very warm or cold temperature can make it ineffective, and therefore, proper storage is required.
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References
- Green W. (2024). Denosumab (Prolia) Injection: A New Approach to the Treatment of Women With Postmenopausal Osteoporosis. P T, 35(10):553–9 - https://pmc.ncbi.nlm.nih.gov/articles/PMC2957751/
- Aubin JE, Bonnelye E. (2025). Osteoprotegerin and its ligand: A new paradigm for regulation of osteoclastogenesis and bone resorption. Osteoporos Int. 11:905–913 - https://pubmed.ncbi.nlm.nih.gov/11193242/
- Sattler A, Schoppet M, et al. Novel aspects on RANK ligand and osteoprotegerin in osteoporosis and vascular disease. Calcif Tissue Int. 74:103–106 - https://pubmed.ncbi.nlm.nih.gov/14523602/
- Nicolopoulos K, Moshi MR, Stringer D, Ma N, Jenal M, Vreugdenburg T. (2025). The clinical effectiveness of denosumab (Prolia®) in patients with hormone-sensitive cancer receiving endocrine therapy, compared to bisphosphonates, selective estrogen receptor modulators (SERM), and placebo: a systematic review and network meta-analysis. Arch Osteoporos. 10;18(1):18.
- Jamshidi, A., Vojdanian, M., Soroush, M. et al. (2025). Efficacy and safety of the biosimilar denosumab candidate (Arylia) compared to the reference product (Prolia®) in postmenopausal osteoporosis: a phase III, randomized, two-armed, double-blind, parallel, active-controlled, and noninferiority clinical trial. Arthritis Res Ther 24, 161 - https://pubmed.ncbi.nlm.nih.gov/35773713/
- Francisco A. (2024). Sylvester, Effects of Digestive Diseases on Bone Metabolism. Pediatric Gastrointestinal and Liver Disease, (1116-1125.e8).
- Savelli,G.,Oliviero,S.,Viceconti,M.,Mattina,M,L,A., (2025). In silico prediction of hip fractures: improved fall modeling and expanded validation across cohorts with diverse risk profiles, Journal of the Mechanical Behavior of Biomedical Materials, 172, (107182) -https://pubmed.ncbi.nlm.nih.gov/40913997/
- Singh, Inderjeet; Jose, Vinu; Patel, Ronak; Arora, Sumit INTP23. (2025). Study 051-14 Investigator Team. Denosumab biosimilar in postmenopausal osteoporotic women: A randomized, assessor-blind, active-controlled clinical trial. Indian Journal of Pharmacology 53(1):p 6-12.
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MARKETER DETAILS
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The contents of this website are for informative purposes only. They are not deliberated to be an alternative to any professional medical prescription and treatment. Seek the advice of a qualified health provider for questions regarding the medical condition. Do not ignore any professional medical advice because of something you have read on this website. This website offers links to other websites, thereby enabling you to go to the other website directly. Therefore, Magicine Pharma isn't responsible for the content of the links in the website or links in the linked websites. The links are provided to assist the visitors and are not approved by any professional health provider.

