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TRASTUZUMAB (HERCEPTIN) 440MG INJECTION

Mfd. by :- (Fulfilled By : Magicine Pharma)

Trastuzumab (Herceptin) 440mg Injection

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Brand name – Trastuzumab (Herceptin)

Generic name – Trastuzumab 

Manufacturer – Roche

Strength – 440mg

Dosage Form – Injection

Composition – Trastuzumab

Indication – Breast Cancer

Storage – 2° – 8° C

Overview of Trastuzumab 440mg injection

Trastuzumab 440mg injection is a target therapy medication that is used in the treatment of breast cancer. It is also used in the treatment of gastric cancers. It is a monoclonal human epidermal growth factor receptor 2 (HER-2) antibody. Trastuzumab 440mg injection is an intravenous injection that is injected by a doctor or a trained nurse.

Pharmacodynamics

The upregulation of HER-2 in cancer cells causes abnormal cell proliferation therefore Trastuzumab binds to these receptors. As a result, Trastuzumab stops the uncontrollable growth of the cancerous cells. In addition, it also initiates antibody-dependent cell-mediated cytotoxicity by using immune cells like natural killer cells.

  • Heartburn
  • Acne 
  • Hot flashes
  • Constipation
  • Diarrhea
  • Loss of appetite
  • Changes in nails
  • Trouble in sleeping
  • Fatigue
  • Sore throat
  • Fever
  • Seizures
  • Dark colouration in urine
  • Nosebleeds
  • Increased heartbeats
  • Numbness of hands and feet

DOSAGE

Trastuzumab 440mg injection is a prescription-based medication that is given intravenously by a doctor or an experienced nurse.

Missed dose

It is advisable to avoid missing any doses of Trastuzumab but in case you miss a dose consult your doctor immediately.

Overdose

In case of an overdose of Trastuzumab 440mg, contact your doctor or any healthcare provider and seek medical attention immediately.

  • Trastuzumab can cause an allergic reaction in some patients hence it is necessary to read the complete composition list.

 

  • Inform the doctor about all the vitamin supplements, herbal medications, and prescription and non-prescription drugs since Trastuzumab can interact with them. 

 

  • It is advisable to avoid pregnancy and breastfeeding during the treatment as Trastuzumab can affect the fetus.

 

  • Avoiding alcohol consumption, driving, and operating heavy machinery while injecting Trastuzumab 440mg injection.

 

  • Inform the doctor about past medical conditions – thrombocytopenia, peripheral neuropathy, cardiovascular conditions.

Q - What is Trastuzumab?

Ans – Trastuzumab 440mg injection is an anticancer medication that is used to treat breast cancer.

Q - How can I take the Trastuzumab injection?

Ans – Trastuzumab 440mg injection is injected intravenously by the doctor and an experienced nurse.

Q – From where can I purchase Trastuzumab injection?

Ans – Purchase Trastuzumab 440mg injection from Magicine Pharma at an affordable price.

Q - Where to store Trastuzumab 440mg?

Ans - It is advisable to store the Trastuzumab 440mg injection at 2° – 8° C

Q - Can I drink alcohol after injecting Trastuzumab?

Ans - Avoid drinking alcohol during the treatment with Trastuzumab 440mg even though no interactions of both are known.

Q - How long is the treatment with Trastuzumab 440mg?

Ans - The doctor decides for how long the treatment with Trastuzumab 440mg will continue depending on the condition, stage, and health of the patient.

Q - Can I drive after consuming Trastuzumab?

Ans - It is advisable to avoid driving and operating heavy machinery as Trastuzumab 440mg injection causes seizures as one of the side effects.

Q - Is it safe to inject Trastuzumab 440mg during pregnancy?

Ans - Trastuzumab 440mg can cause harm to the fetus hence, it is advisable to avoid the pregnancy or consult the doctor for the same.

Q - What is the strength of Trastuzumab?

Ans – Trastuzumab is available as a 440mg injection.

Interactions

With medicines

Trastuzumab can interact with other prescription and non-prescription medicines and interfere with each other’s workings thus contact your doctor if you take any of these –

  • Adalimumab 
  • Certolizumab
  • Epirubicin
  • Idarubicin
  • Ponesimod
  • Tofacitinib
  • Voclosporin

 

With disease

Trastuzumab can interact with some health conditions like –

  • Peripheral neuropathy
  • Thrombocytopenia
  • Pulmonary conditions
  • Cardiovascular conditions

With alcohol

Interactions of alcohol with Trastuzumab are unknown however, it is still advisable to avoid alcohol consumption during the treatment.

Contraindication

Trastuzumab not be consumed by patients who show allergic reactions to it.

 

Alternate Brands

  • Vivitra
  • Canmab
  • Hertraz
  • Trumab
  • Ujvira
  • Herclon

Reference

Trastuzumab: uses, interactions, mechanism of action | DrugBank Online. DrugBank. https://go.drugbank.com/drugs/DB00072

Trastuzumab injection: MedlinePlus drug information. https://medlineplus.gov/druginfo/meds/a699019.html

Trastuzumab drug interactions. Drugs.com. https://www.drugs.com/drug-interactions/trastuzumab-index.html?filter=3

 

Above Content has been reviewed by Professionals