Mfd. by :- Aprazer healthcare (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand name: Abakast-L
Generic name: Abacavir/Lamivudine
Strength: 600 mg/300 mg
Manufacturer: Aprazer
Dosage form: Tablet
Indication: HIV
Storage: Store at room temperature.
Abakast-L is a co-formulation of two antiretroviral agents known as Abacavir and Lamivudine. It is an anti-HIV medicine belonging to the class of Nucleotide analog reverse transcriptase inhibitors. It is used in the treatment of infection caused by HIV (human immunodeficiency virus) namely HIV-1 and HIV-2. The drug is also prescribed often for the treatment of AIDS (acquired immunodeficiency syndrome).
Abakast-L is administered as an oral-use tablet once daily (specifically, as per the doctor’s prescription). It should not be taken in doses greater or less than the prescribed strength. Take the Abakast-L tablet with a glass of water at the same time every day. Do not skip or overdose. Use effective contraception during antiretroviral therapy.
Abacavir (Abakast-L):- It's an NRTI (nucleoside reverse transcriptase inhibitor) that works against the Human Immunodeficiency Virus Type 1 (HIV-1). It is phosphorylated into active metabolites that compete for viral DNA incorporation. Abacavir functions as a chain terminator of DNA synthesis by competitively inhibiting the HIV reverse transcriptase enzyme.
Lamivudine (Abakast-L):- It is a nucleoside reverse transcriptase inhibitor (NRTI) that inhibits viral DNA synthesis in the Human Immunodeficiency Virus Type 1 (HIV-1) and Hepatitis B (HBV) viruses. When phosphorylated, it can produce active metabolites that compete with viral DNA for inclusion. Lamivudine metabolites impede the action of the HIV reverse transcriptase enzyme by incorporating DNA.
Abakast-L tablets may show significant interactions with the following medications, diseases, and alcohol:
Bexarotene
Zalcitabine
Leflunomide
Emtricitabine
Teriflunomide
Hepatotoxicity
Pancreatitis
Renal impairment
Interaction of the Abakast-L tablets with alcohol is not known. Please contact your medical team before consuming any drink that contains alcohol.
Abakast-L tablets are not recommended for use in patients who are:
Hypersensitive
Allergic to Abacavir
Allergic to Lamivudine
Abakast-L tablets may cause certain side effects after administration. Consult your general practitioner regarding the same. Do not take any over-the-counter regimen without a prescription.
Diarrhea
Anxiety
Headache
Trouble sleeping
Loss of strength
Fatigue
Sore throat
Swollen lymph nodes
Loss of appetite
Seizures
Cough
Unusual weakness
Blurred vision
Loss of weight
Nausea
Insomnia
Fever
Chest pain
Allergic reaction
Unusual tiredness
Poor concentration
Confusion
Abnormal dreams
Sensation of spinning
Take Abakast-L tablets as per the prescription given by your medical practitioner. Do not chew or cut these antiviral tablets.
It is ideally advised to not skip any dose of Abakast-L tablets. However, if such a case happens, make sure to contact your medical practitioner.
It is ideally advised to not overdose on Abakast-L tablets. However, if such a case happens, make sure to call a poison helpline or emergency medical center.
Pregnancy
In pregnant women, the use of Abakast-L tablets may cause harm to the unborn baby. Consult your medical practitioner for the right advice.
Breastfeeding
In nursing women, the use of Abakast-L tablets may cause harm to the baby. Consult your medical practitioner for the right advice.
Contraception
Using contraceptives or birth control can be a better option during the therapy with Abakast-L since HIV can be transmitted easily via sexual intercourse.
Driving
Abakast-L tablets may affect your ability to drive. Do not initiate driving if you feel dizzy or tired.
Alcohol
Alcohol can have severe effects on the body when consumed with the Abakast-L tablets.
Kidney
In patients with kidney disease, Abakast-L tablets should be administered with caution.
Liver
In patients with liver disease, Abakast-L tablets should be administered with caution.
Q1- What is Abakast-L?
Ans- Abakast-L is a co-formulation of two antiretroviral agents known as Abacavir and Lamivudine. It is used in the treatment of infection caused by HIV (human immunodeficiency virus)
Q2- What are the side effects of Abakast-L?
Ans- The common side effects of Abakast-L (Abacavir/Lamivudine) are diarrhea, anxiety, headache, fatigue, weakness, fever, chills, sore throat, insomnia, chest pain, confusion, abnormal dream, a sensation of spinning, etc.
Q3- What happens if I miss a dose of Abakast-L?
Ans- It is ideally advised to not skip any dose of Abakast-L tablets. However, if such a case happens, make sure to contact your medical practitioner.
Q4- What happens if I overdose on Abakast-L?
Ans- It is ideally advised to not overdose on Abakast-L tablets. However, if such a case happens, make sure to call a poison helpline or emergency medical center.
Q5- Is Abakast-L safe for use in pregnant women?
Ans- In pregnant women, the use of Abakast-L tablets may cause harm to the unborn baby. Consult your medical practitioner for the right advice.
Q6- Is Abakast-L safe for use in nursing women?
Ans- In nursing women, the use of Abakast-L tablets may cause harm to the baby. Consult your medical practitioner for the right advice.
Q7- What is the available strength of Abakast-L?
Ans- The fixed strength of each Abakast-L tablet is 600 mg/300 mg.
Q8- How is Abakast-L administered?
Ans- Abakast-L (Abacavir/Lamivudine) tablets are administered orally with a glass of water.
Q9- Can I drive after taking Abakast-L?
Ans- Abakast-L tablets may affect your ability to drive. Do not initiate driving if you feel dizzy or tired.
Q10- Is alcohol consumption safe during Abakast-L therapy?
Ans- Alcohol can have severe effects on the body when consumed with the Abakast-L tablets.
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