Abione 250mg Tablet

Every medicine has some side effects that manage on their own as your body gets used to the medicine, but some people may rarely experience severe side effects. In that case, the patient should contact the doctor immediately. Seek medical attention in case of any unusual or severe side effects immediately. Some common side effects of Abione 250mg Tablet include:

• Swelling of a joint
  
• General discomfort
  
• Low potassium levels in the blood (may cause muscle weakness, twitches, or pounding heartbeat)
  
• Swelling (legs, feet, or other areas)
  
• Frequent urination at night
  
• Indigestion
  
• Muscle pain
  
• Fluid buildup in legs or feet
  
• High blood pressure
  
• Urinary tract infection
  
• Diarrhea
  
• High fat levels in the blood (dyslipidemia)
  
• Chest pain
  
• Irregular heartbeat
  
• Rapid heart rate
  
• Bone fracture
• ​Blood in urine
• Rash

• The doctor determines the dosage of Abione 250mg Tablet as per the patient's health and other medical conditions.
• Take it at a fixed time every day exactly as prescribed by the doctor to get effective results.
• This medicine should be taken orally on an empty stomach.
  
•  Avoid breaking the tablets by swallowing them whole with water.
  
• Pregnant or potentially pregnant women should not handle this medicine without gloves.
• In case of an overdose, contact your doctor immediately.

• Abione 250mg Tablet is an anticancer medicine prescribed to treat prostate cancer.
• It works by blocking the action of an enzyme called CYP17.
• This enzyme is involved in the production of the male hormone androgen, as some prostate cancer depends on these hormones to grow and this medicine effectively slows down or stops the progression of cancer by inhibiting the action of this enzyme.
• In this way this tablet cuts off the fuel supply that the cancer cells need to survive.
  

• ​Do not miss any dose of Abione 250mg tablet and take it at the same time for better results. 
  
• Do not double the dose strength in order to catch up with the missed dose.
• Consult your healthcare provider for proper guidance.​
  

• Inform the doctor about your medical history of liver problems, blood pressure, heart disorders, diabetes, or taking any medication for these medical conditions.
• Abione 250mg Tablet is used in adult men to treat advanced prostate cancer that has spread, often together with prednisone to reduce side effects. Always pair it with prednisone to prevent adrenal insufficiency.
• Take this medicine as prescribed by your doctor, once daily on an empty stomach; food can increase medicine levels.
• It may be combined with testosterone-lowering treatment in earlier stages of prostate cancer.
• Serious risks include adrenal insufficiency, liver toxicity, heart problems, and bone fractures; regular monitoring is essential.
  
• Liver function tests are required before starting the treatment and then regularly.
• This medicine is not for women or children; men must use contraceptives during treatment and after stopping.
• Inform your doctor if you have liver problems, heart disease, high blood pressure, diabetes, allergies, or low potassium.
• Tell your doctor about all medicines, supplements, and herbal products you are taking.
• Since it contains lactose and sodium, let your doctor know if you have lactose intolerance or are on a salt-restricted diet
  

• Sonpavde, G., Attard, G., Bellmunt, J., Mason, M. D., Malavaud, B., Tombal, B., & Sternberg, C. N. (2011). The role of abiraterone acetate in the management of prostate cancer: a critical analysis of the literature. European urology, 60(2), 270-278.
  
• Rehman, Y., & Rosenberg, J. E. (2012). Abiraterone acetate: oral androgen biosynthesis inhibitor for treatment of castration-resistant prostate cancer. Drug design, development and therapy, 13-18.
  
• Reid, A. H., Attard, G., Danila, D. C., Oommen, N. B., Olmos, D., Fong, P. C., ... & De Bono, J. S. (2010). Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. Journal of clinical oncology, 28(9), 1489-1495.
  
• Loriot, Y., Bianchini, D., Ileana, E., Sandhu, S., Patrikidou, A., Pezaro, C., ... & Massard, C. (2013). Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100). Annals of oncology, 24(7), 1807-1812.
  
• De Bono, J. S., Logothetis, C. J., Molina, A., Fizazi, K., North, S., Chu, L., ... & Scher, H. I. (2011). Abiraterone and increased survival in metastatic prostate cancer. New England Journal of Medicine, 364(21), 1995-2005.​