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ABIRATERONE ACETATE 250MG TABLET (ABIRACINE)

Mfd. by :- Arechar Healthcare (Fulfilled By : Magicine Pharma)

Abiraterone Acetate  250mg Tablet (Abiracine)

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand name: Abiracine
Generic name: Abiraterone Acetate
Manufacturer: Arechar
Strength: 250mg
Dosage form: Tablet
Composition: Abiraterone Acetate
Indication: Prostate cancer
Storage: Store at room temperature 

Overview 

Abiracine (Abiraterone Acetate) tablet is used in the treatment of prostate cancer. It belongs to a class of medication known as androgen biosynthesis inhibitors. Abiraterone 250mg tablet works by restructuring the activity of anti-testosterone and helps to stop the multiplication of cancer cells. It is important to take the Abiracine tablet as prescribed by your doctor. The recommended dose of Abiraterone 250mg tablet is decided by a doctor according to your previous medical condition and response to the treatment. If you experience any signs and symptoms while receiving Abiraterone 250mg tablet, inform your doctor immediately. 

Pharmacodynamics of Abiraterone 250mg tablet

Abiraterone Acetate is associated with decreases in PSA (Prostate-specific antigen) levels, tumor shrinkage (as evaluated by RECIST criteria), radiographic regression of bone metastases, and improvement in pain. Abiraterone 250mg tablets selectively and irreversibly inhibit CYP17, an enzyme required for androgen biosynthesis which is expressed in testicular, adrenal, and prostatic tumor tissues. Inhibits the formation of the testosterone precursors dehydroepiandrosterone (DHEA) and androstenedione.

Usage of Abiraterone 250mg tablet

Abiracine is an anti-cancer medication and this medication works by blocking the activity of an enzyme (CYP17) that is responsible for the production of androgen. It helps to slow down the multiplication of cancer cells. Do not take Abiraterone 250mg tablet in the wrong way as it may lead to some serious side effects. It is advised not to change your regular dosing schedule without taking suggestions from your doctor. This medication is not recommended for use in children and women. Follow the instructions given by your healthcare provider to avoid any further complications. Store this medicine at room temperature and protect it from heat and moisture. 

Side effects of Abiraterone 250mg tablet 

This medicine may cause some common side effects. Discuss the risks and benefits of the Abiracine tablet with the doctor before starting the treatment.

Common side effects

  • Vomiting

  • Swelling 

  • Anemia 

  • Increased levels of blood fat

  • Confusion

  • Sweating

  • Irritability

  • Cough 

  • Joint pain

  • Nausea

  • Headache

  • Swelling 

  • High cholesterol 

  • Fast heartbeat

  • Diarrhea

  • High blood pressure

  • Fever

  • Hypersensitivity 

  • Dizziness

  • Muscle pain

  • Headache

  • Decreased white blood cell count 

  • Urinary tract infection 

  • Altered blood sugar levels 

Note - immediately contact your healthcare provider if any side effects occur.

 

Dosage of Abiraterone 250mg tablet

Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule of the Abiracine tablet. 

Missed dose 

  • It is advisable not to miss a dose. If you miss a scheduled dose of Abiraterone 250mg tablet, contact your doctor immediately. 

Overdose 

  • In case of an overdose of Abiracine tablets, the doctor will provide emergency medical treatment.

Warnings 

Before starting treatment with Abiraterone 250mg tablet, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk. 

  •  Contraception 

    • Use suitable methods of contraception while taking Abiracine tablets. 

  • Children and adolescents 

  • Abiracine (Abiraterone 250mg tablet) is not recommended for use in children and adolescents. 

Warnings for female 

  • Pregnancy

    • Abiracine (Abiraterone 250mg tablet) is not recommended for use in women. 

  • Breastfeeding 

    • Abiracine (Abiraterone Acetate) tablet is not recommended for use in women.

Precautions while taking Abiraterone 250mg tablet

  • Inform your doctor if you experience any side effects like- nausea, fever, anemia, headache, diarrhea, blurred vision, vomiting, high cholesterol, etc. 

  • Contact your healthcare provider beforehand, if you have a heart, kidney, or any serious problem.

  • Abiracine tablets may increase the risk of infections. 

  • Avoid drinking alcohol. 

Cautions 

  • Do not skip the dose of Abiracine tablets. 

  • Do not crush or break the tablet.

  • Not recommended in chfordren and women.

  • Do not drive or operate heavy machinery.

Q1. What is Abiracine (Abiraterone Acetate)?

Ans. Abiraterone 250mg tablet is used in the treatment of prostate cancer. It belongs to a class of medication known as androgen biosynthesis inhibitors. Abiracine tablet helps to slow down the multiplication of cancer cells.

Q2. How does Abiracine (Abiraterone Acetate) work?

Ans. Abiracine is an anti-cancer medication and this medication works by blocking the activity of an enzyme (CYP17) that is responsible for the production of androgen. 

Q3. What are the side effects of Abiraterone 250mg tablet?

Ans. Some common side effects are:- nausea, hypersensitivity, fever, anemia, headache, diarrhea, blurred vision, vomiting, cough, high cholesterol, etc.

Q4. How to take this medicine?

Ans. It is important to take the Abiracine tablet as prescribed by your doctor. 

Q5. Can I consume alcohol while taking Abiraterone 250mg tablet?

Ans. Please consult your doctor before consuming alcohol. 

Q6. What happens if I miss a dose? 

Ans. If you miss a scheduled dose of Abiracine tablet, contact your doctor immediately.

Q7. What are the storage conditions for Abiraterone 250mg tablet?

Ans. Store this medicine at room temperature. Keep it away from direct heat and light.

Q8. In what strength is it available? 

Ans. Abiracine (Abiraterone Acetate) tablet is available in the strength of 250mg. 

Q9. Can I take this medicine during pregnancy? 

Ans. This medication is not recommended during pregnancy.

Q10. What are the self-care tips? 

Ans. Keep yourself hydrated and maintain good nutrition. 

Q11. Can I consume alcohol while taking Abiraterone 250mg tablet?

Ans. Please consult your doctor before consuming alcohol. 

Q12. Does abiraterone 250mg tablet affect liver function? 

Ans. Please consult your doctor before consuming this drug.

Q13. Can I drive after taking Abiraterone 250mg tablet? 

Ans. Abiracine tablets may decrease your ability to drive or affect your vision. Do not drive if any symptoms occur.

 

Interactions 

Abiracine tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interactions

  • Carbamazepine
  • Loperamide
  • Tamoxifen
  • Oxycodone
  • Leflunomide
  • Rifampicin
  • Edoxaban

Disease Interactions

  • Cardiovascular disease.
  • Hepatic Impairment.

Alcohol Interaction 

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.

Contraindication

  • Do not take this medicine if you are allergic to Abiraterone Acetate.
  • Abiracine (Abiraterone 250mg tablet) is not recommended in patients known to be hypersensitive.

Alternate Brands

Reference –

Abiraterone Interactions Checker. Drugs.com. https://www.drugs.com/drug-interactions/abiraterone.html

Abiraterone: MedlinePlus drug information. https://medlineplus.gov/druginfo/meds/a611046.html

Abiraterone: Uses, interactions, mechanism of action | DrugBank Online. DrugBank. https://go.drugbank.com/drugs/DB05812

Above Content has been reviewed by Professionals