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AFANAT 40MG TABLET

Mfd. by :- Natco (Fulfilled By : Magicine Pharma)

Afanat 40mg Tablet

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

Don't have Prescription ?

Brand name – Afanat

Generic name – Afatinib

Manufacturer – Natco

Strength – 40mg/30mg

Dosage Form – Tablets

Composition – Afatinib

Indication – Lung Cancer

Storage – at room temperature

 

Overview of Afanat

Afanat 40mg tablets is a chemotherapy medication that is used in the treatment of non-small cell lung cancer. The generic name of this medication is Afatinib. It is a 4-anilinoquinazoline tyrosine kinase inhibitor that showcases antineoplastic properties that is it inhibits the growth of cancerous cells. It is a medication that has to be prescribed by the doctors.

Pharmacodynamics

Afanat is the first-line treatment for non-small cell lung cancer. It is a potent and irreversible inhibitor of EGFR. EGFR means epidermal growth factor receptor. When mutations in EGFR arise it consequently leads to uncontrollable growth of the cancerous cells of the lung. Afanat binds to the tyrosine kinase of these growth factors and as a result, blocks their signals. In addition, it stops the auto phosphorylation. Therefore this medication stops the uncontrollable cell division and spreading of the cancerous cells.

  1. Diarrhea
  2. Nausea
  3. Vomiting
  4. Fever
  5. Cough
  6. Nose bleeds
  7. Dry skin
  8. Acne
  9. Nose bleeds
  10. Weight gain
  11. Blisters of skin
  12. Loss of appetite
  13. Cracked or swollen lips
  14. Rashes due to sun exposure
  15. Dark coloration of urine
  16. Shortness of breath
  17. Eye pain
  18. Increased bruises
  19. Irregular heart rate
  20. Nail infection
  21. Sensitivity to light
  22. Yellowing of skin and eyes
  23. Painful urination

The doctor prescribes this medicine hence, it is advisable to follow the prescription. Afanat 40mg tablets or Afanat 30mg tablets are taken orally every day without a meal

Missed dose

It is advisable to avoid missing any doses. In case you miss a dose of Afanat 40mg tablets consult your doctor immediately.

Overdose

In case of an overdose of Afanat 40mg (30mg) tablets, immediately contact your doctor or any healthcare provider and seek medical attention.

  1. Afanat can cause an allergic reaction in some patients. Therefore it is mandatory to gather complete information about the composition. Also, consult the doctor in case of any issues.
  2. Inform the doctor about all the vitamin supplements, herbal medications, and prescription and non-prescription drugs. 
  3. The treatment with Afanat 40mg tablets increases the sensitivity of the skin thus it is advisable to avoid sunlight or cover completely and  wear a sunscreen
  4. Consult the doctor if you are planning a pregnancy as Afanat 30mg can cause harm to the fetus.
  5. It is advisable to avoid breastfeeding during the treatment with Afanat tablets.
  6. Avoid alcohol consumption while consuming Afanat tablets.
  7. Also, operating heavy machinery is not advisable.

Q - What is Afanat?

Ans - Afanat 40mg tablets is an anticancer tablet that is used in the treatment of lung cancer.

Q - How can I take Afanat 40mg tablets?

Ans - Afanat 40mg tablets are taken orally every day strictly without meals. However, it is advisable to follow the prescription given by the doctor.

Q - Where to store Afanat tablets?

Ans - It is advisable to store Afanat 40mg tablets at room temperature.

Q - Can I drink alcohol with Afanat tablets?

Ans - Avoid drinking alcohol while using Afanat tablets even though no interactions of both are known.

Q - How long is the treatment with Afanat 40mg tablets?

Ans - The doctor decides the course of treatment with Afanat 40mg tablets (30mg) depending on the stage of the cancer, and the health of the patient.

Q - Can I drive after taking Afanat 40mg/30mg tablets?

Ans - It is advisable to avoid driving and operating heavy machinery as treatment with Afanat 40mg tablets can lead to dizziness.

Q - Are Afanat tablets safe to take during pregnancy?

Ans - It is advisable to avoid the pregnancy since Afanat 40mg tablets can cause harm to the fetus.

Q - What is the strength of Afanat tablets?

Ans - Afanat tablets are available in two strengths – 40mg and 30mg.

Afanat 40mg (30mg) tablets can interact with some other prescription and non-prescription medicines and interfere with each other’s workings or increase the side effects. Contact your doctor if you are taking any of these medicines –

  • Itraconazole
  • Cyclosporine
  • Erythromycin
  • Carbamazepine
  • Phenytoin
  • Rifampin
  • Phenobarbital

With disease

Some diseases may show interactions with Afanat tablets. Hence, consult your doctor if you have any of these conditions –

  • Lung problems
  • Eyes problems
  • Cardiovascular conditions
  • Renal problems
  • Liver diseases

With alcohol

Interactions of alcohol with Afanat are unknown. However, it is still advisable to avoid alcohol consumption during the treatment.

Contraindication

Afanat 30mg tablets (40mg) should not be consumed by patients who show allergic responses to it.

Alternate Brands

  • Giotrif
  • Xovoltib

 

Reference

Afatinib: MedlinePlus Drug Information MedlinePlus. Available at: https://medlineplus.gov/druginfo/meds/a613044.html.

Afatinib Uses, Interactions, Mechanism of Action | DrugBank Online. Available at: https://go.drugbank.com/drugs/DB08916.

Afatinib (oral route) description and brand names (2023) Mayo Clinic. Available at: https://www.mayoclinic.org/drugs-supplements/afatinib-oral-route/description/drg-20061227

Above Content has been reviewed by Professionals