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28 Tablet in Bottle
Afatinib
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Overview
Afanat 40mg tablet is a chemotherapy-based anticancer medication that is prescribed to treat non-small cell lung cancer. The generic name of this medication is Afatinib. Afatinib is the first-line treatment for non-small cell lung cancer. It is usually prescribed to patients with the EGFR gene mutation.
Lung Cancer
Afanat 40mg tablets may cause some side effects that vary from one patient to another. Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.
Common side effects include:
Diarrhea
Nausea
Vomiting
Fever
Cough
Nose bleeds
Dry skin
Acne
Nose bleeds
Weight gain
Blisters of skin
Loss of appetite
Cracked or swollen lips
Rashes due to sun exposure
Dark coloration of urine
Shortness of breath
Eye pain
Increased bruises
Irregular heart rate
Seek medical attention in case of any unusual or severe side effects immediately.
The doctor determines the dosage and duration of Afanat 40mg tablets as per the patient's health condition and other medical factors. This tablet is usually taken orally on an empty stomach. Follow your doctor's instructions properly during the treatment. Don't overdose or miss a dose.

Alcohol
caution
The interaction of alcohol with this drug is still unknown, but you should avoid the consumption of alcohol while taking Afanat 40mg tablets

Pregnancy
consult your doctor
Do not take Afanat 40mg tablet during pregnancy, as it is a highly unsafe medicine for the fetus.

Breast Feeding
consult your doctor
Afanat 40mg tablet is unsafe to use during breastfeeding as it may cause toxicity to the baby.

Driving
danger
Afanat 40mg tablets may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.

Kidney
caution
Consumption of Afanat 40mg tablets should be avoided without informing the doctor if you have any kidney-related issues.

Liver
caution
Consumption of Afanat 40mg tablets should be avoided without informing the doctor if you have any liver-related issues.
It is advisable to avoid missing any doses. In case you miss a dose of Afanat 40mg tablets consult your doctor immediately.
Afanat 40mg tablet is an anticancer medicine that is used in the treatment of non-small cell lung cancer.
It is advisable to avoid the Afanat 40mg tablet during pregnancy as it can cause harm to the fetus.
It is advisable to avoid driving and operating heavy machinery while taking Afanat 40mg tablets, as it may cause dizziness.
The doctor decides the course of treatment with Afanat 40mg tablets depending on the stage of the cancer and the health of the patient.
Afanat 40mg tablets should be taken orally without meals. However, it is advisable to follow the prescription given by the doctor.
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1. Joshi, M., Rizvi, S. M., & Belani, C. P. (2015). Afatinib for the treatment of metastatic non-small cell lung cancer. Cancer management and research, 75-82.
2. Kumar, S., & Agrawal, R. (2014). Next generation tyrosine kinase inhibitor (TKI): afatinib. Recent patents on anti-cancer drug discovery, 9(3), 382-393.
3. Kim, Y., Lee, S. H., Ahn, J. S., Ahn, M. J., Park, K., & Sun, J. M. (2019). Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib. Cancer research and treatment: official journal of Korean Cancer Association, 51(2), 502-509.
4. Giordano, P., Manzo, A., Montanino, A., Costanzo, R., Sandomenico, C., Piccirillo, M. C., ... & Morabito, A. (2016). Afatinib: An overview of its clinical development in non-small-cell lung cancer and other tumors. Critical reviews in oncology/hematology, 97, 143-151.
5. Saber, A., Hiltermann, T. J. N., Kok, K., & Groen, H. J. M. (2016). Resistance mechanisms after tyrosine kinase inhibitors afatinib and crizotinib in non-small cell lung cancer, a review of the literature. Critical reviews in oncology/hematology, 100, 107-116.
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