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EXEMESTANE 25MG TABLET (AROMASIN)

Mfd. by :- Pfizer (Fulfilled By : Magicine Pharma)

Exemestane 25mg Tablet (Aromasin)

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Overview

Aromasin is an anti-cancer medicine. It is approved for the treatment of estrogen receptor-positive breast cancer in postmenopausal women. This medication comprises exemestane (an antineoplastic aromatase inhibitor). It is available in the form of oral tablets of strength 25mg. In some cases, it is also used as an adjuvant treatment for breast cancer. It is usually given to women who have received two to three years of tamoxifen. This drug is taken orally as per the strength prescribed by the doctor.

Pharmacodynamics of Exemestane 25mg tablet

Aromatase is an enzyme found in the adrenal glands that transform hormones into estrogen. Aromatase inhibitors (AIs) like Aromasin (Exemestane) are medications that limit the function of aromatase in the adrenal glands, lowering estrogen levels. Selective AIs (SAIs) lower estrogen levels while leaving other steroid hormones generated by the adrenal gland alone.

Side Effects of Exemestane 25mg Tablet

The following are some common adverse effects of taking Aromasin (Exemestane 25mg tablet). Contact your healthcare provider if you have any such concerns.

  • Decreased urine output
  • Diarrhea
  • Headache 
  • Sore throat
  • Difficulty with speaking
  • Joint pain
  • Loss of hair
  • Runny nose
  • Stomach upset
  • Dilated neck veins
  • Dizziness 
  • Slow speech
  • Unpleasant breath odor
  • Hot flashes
  • Unusual tiredness
  • Vomiting of blood
  • Weight gain
  • Yellow eyes or skin
  • Double vision

Dosage of Exemestane 25mg tablet

Take Aromasin (Exemestane 25mg tablet) as per the prescription provided by your doctor. Plus, make sure to not cut or chew the tablets during administration.

Missed dose

If you forget to take a dose of Aromasin (Exemestane 25mg tablets), consult your doctor. Don’t double up the next dose to cope with the missed one unless your doctor recommends it.

Overdose 

An overdose of Aromasin (Exemestane 25mg tablets) can lead to severe side effects. These may include chest pain and fainting. Kindly contact your nearest doctor immediately. 

General warnings while taking Exemestane 25mg tablet

  • Tell your medical practitioner about the medicines you take and the diseases you may have already. This helps in making the right decisions about your treatment plan.
  • Do not drink alcohol during your treatment with Aromasin (Exemestane 25mg tablets). It may interact with this drug.
  • Use effective contraception during sexual intercourse when you are on therapy with Aromasin tablets. 
  • If you have an existing liver or kidney disease, administer Aromasin tablets with extreme caution.

Warnings for females

  • Pregnancy
    • During pregnancy, the use of Aromasin (Exemestane 25mg tablets) may not be safe. Contact your medical practitioner to know the risks of using this drug.
  • Breastfeeding 
    • During breastfeeding, the use of Aromasin (Exemestane 25mg tablets) may not be safe. Contact your medical practitioner to know the risks of using this drug.

Precautions 

  • Do not administer Aromasin 25mg (Exemestane) tablets without a prescription.
  • Do not cut or chew this medication while administering it.
  • Store this drug away from children’s reach. 
  • Keep Aromasin tablets away from direct moisture and heat.

Q1- What is Aromasin (Exemestane 25mg Tablet)? 

A- Aromasin is an anti-cancer medicine. It is approved for the treatment of estrogen receptor-positive breast cancer in postmenopausal women.

Q2- What are the side effects of Aromasin (Exemestane 25mg Tablet)? 

A- The side effects of Aromasin (Exemestane 25mg tablets) include diarrhea, headache, sore throat, joint pain, cough, weight gain, hot flashes, unusual tiredness,

Q3- How to take Aromasin (Exemestane 25mg Tablet)?

A- Take Aromasin (Exemestane 25mg tablets) as per the prescription provided by your doctor. Plus, make sure to not cut or chew the tablets during administration.

Q4- Is it safe to take Aromasin (Exemestane 25mg Tablet) during pregnancy?

A- During pregnancy, the use of Aromasin (Exemestane 25mg tablets) may not be safe. Contact your medical practitioner to know the risks of using this drug.

Q5- Is it safe to take Aromasin (Exemestane 25mg Tablet) during breastfeeding?

A- During breastfeeding, the use of Aromasin (Exemestane) tablets may not be safe. Contact your medical practitioner to know the risks of using this drug.

Q6- Is it safe to drive after taking Aromasin (Exemestane 25mg Tablet)?

A- Do not drive after taking Aromasin (Exemestane) tablets if you feel dizzy.

Q7- Can I consume alcohol during Aromasin (Exemestane) therapy?

A- Do not drink alcohol during your treatment with Aromasin (Exemestane 25mg tablets). It may interact with this drug.

Q8- How to store Aromasin (Exemestane 25mg tablet)?

A- Store Aromasin (Exemestane) tablets at room temperature.

Q9- What happens if I overdose on Aromasin (Exemestane 25mg tablet)?

A- An overdose of Aromasin (Exemestane 25mg tablets) can lead to severe side effects. These may include chest pain and fainting. Kindly contact your nearest doctor immediately.

Q10- What happens if I miss a dose of Aromasin (Exemestane 25mg tablet)?

A- If you forget to take a dose of Aromasin (Exemestane) tablets, consult your doctor. Don’t double up the next dose to cope with the missed one unless your doctor recommends it.

Interactions

Aromasin (Exemestane 25mg tablet) may interact with these:

Medicine Interactions

  • Thalidomide 
  • Secobarbital 
  • Oxcarbazepine 
  • Lorlatinib
  • Carbamazepine 
  • Fostamatinib 
  • Amobarbital 

Disease Interactions

  • Osteoporosis 
  • Vitamin D deficiency

Alcohol Interactions

  • Do not drink alcohol during your treatment with Aromasin (Exemestane 25mg) tablets. It may interact with this drug.

Contraindications

It is advisable to not take Aromasin (Exemestane 25mg tablet) under the following conditions.

  • Low vitamin D levels
  • Pregnancy
  • Breastfeeding 
  • Low bone density

Alternate Brands

The following are some alternatives to Aromasin (Exemestane 25mg tablet).

  • Xmalon
  • Xemasin
  • Exetraz
  • Exeget

 

Reference

 

Exemestane Interactions Checker. Drugs.com. https://www.drugs.com/drug-interactions/exemestane.html

Exemestane: MedlinePlus drug information. https://medlineplus.gov/druginfo/meds/a607006.html

Exemestane: uses, interactions, mechanism of action | DrugBank Online. DrugBank. https://go.drugbank.com/drugs/DB00990

Above Content has been reviewed by Professionals