Mfd. by :- Aprazer healthcare (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand name: Dasakast
Generic name: Dasatinib
Strength: 70 mg
Manufacturer: Aprazer
Dosage form: Tablet
Indication: Blood Cancer
Storage: Store at room temperature.
Dasakast is an anticancer formulation comprising Dasatinib. It belongs to the class of small molecule antineoplastic breakpoint cluster region-abelson (BCR-ABL) inhibitors. This medicine is used in the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Dasakast is administered as an oral-use tablet with a glass of water. It should be taken in the same strength as prescribed by your medical practitioner. The medication should never be missed or overdosed on unless recommended by your GP.
Dasatinib, at nanomolar concentrations, represses the latter kinases: BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA2, and PDGFRβ. Based on modeling studies, dasatinib is predicted to bind to varied conformations of the ABL kinase. In vitro, dasatinib was active in leukemic cell lines denoting variants of imatinib mesylate sensitive and resistant condition. The compound hindered the growth of chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) cell lines overexpressing BCR-ABL.
Dasakast (Dasatinib) tablets can interact with medicines, diseases, and alcohol. As per the severity of interactions, the following should be taken into consideration.
Cisapride
Diclofenac
BCG vaccine
Adalimumab
Alteplase
Dabigatran
Hepatic impairment
Heart and blood vessel disorder
Alcohol can show significant interactions with the ingredients of Dasakast (Dasatinib) tablets. Please talk to your medical practitioner regarding the same prior to the therapy.
The following are some of the contraindications of Dasakast (Dasatinib) tablets:
Anemia, neutropenia, and thrombocytopenia
Anticoagulant therapy, bleeding, GI bleeding, and intracranial bleeding
Edema, pericardial effusion, and pleural effusion
Lactase deficiency
Tumor lysis syndrome
Pulmonary hypertension
Geriatric
Children, growth inhibition, infants, and neonates
Pregnancy
Breast-feeding
The following are some of the common adverse effects that are associated with the use of Dasakast tablets.
Joint pain
Bleeding gums
Constipation
Loss of appetite
Difficulty in breathing
Fatigue
Nausea
Infection
Low blood platelets
Muscle pain
Bone pain
Unusual tiredness
Chills
Skin rash
Weight loss
Tingling in the arms and feet
Vomiting
Anxiety
Diarrhea
Blurred vision
Swelling in your feet
Irregular heartbeat
Sore throat
Headache
Nasal congestion
Anemia
Unusual weakness
Difficulty with swallowing
Itching
Coughing up blood
Body pain
Dizziness
Weight gain
Take Dasakast (Dasatinib) tablets as per the prescription given by your general practitioner. Do not increase/decrease the dose strength.
Do not skip the dose of Dasakast (Dasatinib) tablets. If you miss a dose, make sure to tell your healthcare provider about the same.
Do not overdose on Dasakast (Dasatinib) tablets. If you experience the symptoms of overdose, make sure to tell your healthcare provider about the same.
Pregnancy
During pregnancy, Dasakast (Dasatinib) tablets should be administered only if the doctor prescribes them. Be sure to seek the advice of your health practitioner.
Breastfeeding
During breastfeeding, Dasakast (Dasatinib) tablets should be administered only if the doctor prescribes them. Be sure to seek the advice of your health practitioner.
Kidney
In kidney disease, Dasakast (Dasatinib) tablets should be given with caution.
Liver
In kidney disease, Dasakast (Dasatinib) tablets should be given with caution.
Alcohol
Alcohol and Dasakast (Dasatinib) tablets can interact with each other and cause severe reactions. Be sure to seek the advice of your health practitioner.
Q1- What is Dasakast?
Ans- Dasakast is an anticancer formulation comprising Dasatinib. This medicine is used in the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL).
Q2- What are the side effects of Dasakast?
Ans- The common side effects of Dasakast (Dasatinib) tablets are chills, nausea, infection, bleeding gums, weight gain, vomiting, anxiety, muscle pain, bone pain, etc.
Q3- What happens if I miss a dose of Dasakast?
Ans- Do not skip the dose of Dasakast (Dasatinib) tablets. If you miss a dose, make sure to tell your healthcare provider about the same.
Q4- What happens if I overdose on Dasakast?
Ans- Do not overdose on Dasakast (Dasatinib) tablets. If you experience the symptoms of overdose, make sure to tell your healthcare provider about the same.
Q5- Is Dasakast safe for use in pregnant women?
Ans- During pregnancy, Dasakast (Dasatinib) tablets should be administered only if the doctor prescribes them. Be sure to seek the advice of your health practitioner.
Q6- Is Dasakast safe for use in nursing women?
Ans- During breastfeeding, Dasakast (Dasatinib) tablets should be administered only if the doctor prescribes them. Be sure to seek the advice of your health practitioner.
Q7- What is the available strength of Dasakast?
Ans- Dasakast (Dasatinib) tablet is available with a strength of 70 mg.
Q8- How is Dasakast administered?
Ans- Dasakast (Dasatinib) tablet is administered orally with a glass of water.
Q9- Can I drive after taking Dasakast?
Ans- Do not drive after taking Dasakast (Dasatinib) tablets if you experience symptoms like dizziness and blurred vision.
Q10- Is alcohol consumption safe during Dasakast therapy?
Ans- Alcohol and Dasakast (Dasatinib) tablets can interact with each other and cause severe reactions. Be sure to seek the advice of your health practitioner.
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