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EMFOVIR

Mfd. by :- Arechar Healthcare (Fulfilled By : Magicine Pharma)

Emfovir

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Emfovir 

Generic Name: Tenofovir Disoproxil Fumarate & Emtricitabine 

Manufacturer: Arechar Healthcare 

Strength: 300mg,200mg 

Dosage: Tablets 

Indications: HIV  

Storage: Store at room temperature 

Overview 

Emfovir is a combination of two medications and it contains Tenofovir Disoproxil Fumarate and Emtricitabine as active ingredients. This tablet specifically belongs to a group of medications known as antiretrovirals. This medication is used to treat HIV (human immunodeficiency virus) infection and managing AIDS (Acquired immunodeficiency syndrome). Emfovir tablets help in decreasing the amount of virus from the body. To avoid side effects like diarrhea and dizziness, keep yourself hydrated and get plenty of rest.   

Pharmacodynamics  

Emtricitabine (Emfovir): It is a synthetic nucleoside analog of cytidine. This compound is phosphorylated by cellular enzymes for the formation of emtricitabine 5'-triphosphate. Emtricitabine works to inhibit the activity of the HIV-1 reverse transcriptase (RT) through competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporating it into nascent viral DNA resulting in chain termination. The compound is a weak inhibitor of mammalian DNA polymerase alpha, beta, epsilon, and mitochondrial DNA polymerase gamma.  

Tenofovir Disoproxil Fumarate (Emfovir):- It needs initial diester hydrolysis for converting it to tenofovir and subsequent phosphorylations through cellular enzymes for forming tenofovir diphosphate. This compound is particularly an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. It works to inhibit HIV-1 RT activity by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination. Tenofovir Disoproxil Fumarate is known to be a weak inhibitor of mammalian DNA polymerases alpha, beta, and mitochondrial DNA polymerase gamma.  

Usage of Emfovir  

Emfovir (Tenofovir Disoproxil Fumarate and Emtricitabine) is used to treat patients with HIV (human immunodeficiency virus) and this anti-HIV medicine is a temporary cure. It lowers your risk of getting HIV-related infections. Take this medicine as advised by your physician and try not to miss your regular dosing schedule. Somehow you forgot to take the Emfovir tablet, consult your healthcare provider as soon as possible. 

Interactions  

Emfovir tablets may interact with other medicines you might take, diseases you have/had, and alcohol. Make sure to read the interactions below before administering the tablets.  

Alcohol Interaction 

It is not known whether Emfovir interacts with alcohol or not. Consult a qualified medical professional before consuming alcohol with this medicine.  

Medicine Interactions 

Methotrexate 

Tobramycin  

Gentamicin 

Leflunomide 

Efavirenz  

Cisplatin 

Disease Interactions 

Renal dysfunction  

Hepatic Impairment  

Contraindications  

Do not administer Emfovir tablets if you have an allergy to Emtricitabine and Tenofovir Disoproxil Fumarate. 

Emfovir tablets are not indicated for use in patients having hypersensitivity.  

Emfovir tablets are not recommended for use in patients having kidney impairment.  

Alternate Brands 

Tofocom 

Ricovir EM  

Tavin EM  

Tenvir EM 

Side Effects  

Emfovir (Tenofovir Disoproxil Fumarate and Emtricitabine) tablets may cause certain side effects. Make sure to inform a qualified doctor about the same and know the ways to tackle them.  

Common Side Effects  

Unusual tiredness  

Confusion  

Cough  

Unusual weakness  

Indigestion  

Constipation 

Loss of weight 

Nausea 

Insomnia 

Loss of appetite  

Diarrhea 

Fever  

Chills  

Loss of strength  

Fatigue  

Sore throat 

Serious Side Effects 

Redness of skin 

Blood in urine 

Blurred vision  

Irregular heartbeat 

Seizures  

Abnormal dream  

Taste changes  

Swollen lymph nodes 

Dosage  

Normal Dose  

Take Emfovir tablets as per your doctor’s prescription. Do not adjust the dose on your own. Do not crush, chew, or break the tablets.  

Missed Dose

If you miss a dose, be sure to contact your healthcare professional to get the needed guidance. Do not increase the strength of the dose to cope with the skipped dose.  

Overdose

If symptoms of overdose occur, be sure to contact your healthcare professional or call an emergency medical helpline. You will be provided with supportive care.  

Warnings and Precautions  

General Warnings 

Tell your doctor about the medicines you already administer, including supplements.  

Do not administer Emfovir tablets without a prescription. 

Emfovir tablets may cause several allergic reactions in some patients. If you experience such side effects, consult a physician.  

If you are suffering from liver or/and kidney impairment, do not administer Emfovir tablets without discussing their risks and benefits with your doctor. 

Warnings for Females  

Pregnancy 

During pregnancy, Emfovir tablets may cause harm to the developing baby. It is advised to avoid its administration.  

Breastfeeding  

During breastfeeding, Emfovir tablets may cause harm to the new-born baby. It is advised to avoid its administration.  

Special Precautions  

Do not crush or chew Emfovir tablets.  

Do not miss a dose of Emfovir.  

Adjusting the dose on your own can cause adverse reactions. Do not overdose.  

Q1. What is Emfovir (Tenofovir disoproxil fumarate and Emtricitabine)? 

Ans. Emfovir (Tenofovir disoproxil fumarate and Emtricitabine) tablet is an antiviral medication that prevents the human immunodeficiency virus (HIV) from multiplying in your body.  

Q2. How do Emfovir tablets work? 

Ans. Emfovir (Tenofovir disoproxil fumarate and Emtricitabine) works to boost immunity in order to fight against HIV infection. It tends to increase the CD4 cell count in the blood. 

Q3. Can I drink alcohol while taking Emfovir tablets?  

Ans. It is not known whether Emfovir interacts with alcohol or not. Consult a qualified medical professional before consuming alcohol with this medicine.   

Q4. Can I take Emfovir tablets in liver impairment? 

Ans. If you are suffering from a liver impairment, do not administer Emfovir tablets without discussing their risks and benefits with your doctor.  

Q5. What happens if I miss a dose of Emfovir tablets?  

Ans. If you miss a dose, be sure to contact your healthcare professional to get the needed guidance. Do not increase the strength of the dose to cope with the skipped dose.  

Q6.  What are the side effects of Emfovir tablets? 

Ans. Some common side effects of Emfovir tablets are fatigue, diarrhea, fever, chills, blurred vision, weight loss, sore throat, headache, nausea, taste change, stomach ache, peripheral neuropathy, and abnormal dreams. 

Q7. In what strength are Emfovir tablets available?  

Ans. It is available in the strength of 300mg/200mg. 

Q8.  Can I drive after taking Emfovir tablets?  

Ans. Emfovir tablets may affect your vision. Do not drive or operate heavy machines if such symptoms occur.  

Q9. Can I take Emfovir tablets during pregnancy?  

Ans. Emfovir tablets are not indicated for use during pregnancy. 

Q10. What are the storage conditions for Emfovir tablets? 

Ans. Store Emfovir tablets at room temperature. 

Above Content has been reviewed by Professionals