Mfd. by :- Hetro healthcare ltd. (Fulfilled By : Magicine Pharma)

Gefitinib 250mg Tablet (Gefitero)


Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand name- Gefitero 

Generics- Gefitinib 

Manufacturer- Hetro healthcare ltd.  

Dosage form- Tablet 

Route of Administration- oral 

Strength- 250mg 

Composition- Gefitinib 

Packaging- Strip 

Indication- non-small cell lung cancer (NSCLC). 

Storage- Store at room temperature (10-30°C) 

Class of drug- Anti-Neoplastics  

Mechanism of Action 

It works by blocking the action of abnormal protein that signals cancer cells to multiply. This in turn helps to slow or inhibit the spread of cancer cells 

Side effects- 

The most common side effects of gefitero include nausea, rash, vomiting and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult the doctor if it happens. It makes the patient sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out.  


It is the study of drug effects and what the medicine does to the body 

It inhibits the intracellular phosphorylation of tyrosine kinase associated with epidermal growth factor (EGFR). 


Study of what body does to the medicine.Gefitinib is absorbed slowly after oral administration as it has bioavailability of 60%. Elimination is through metabolism (primarily CYP 3A4) and excretion in feces.  

Bioavailability rate 

Gefitero is slowly absorbed, with peak plasma levels in 3-7 hours after dosing and mean oral bioavailability of 60% 

Shelf life  

Shelf life is the time period over which the concentration of the active medicinal ingredient in the formulation lowers by 10 percent from its value at time of manufacture. 

Its shelf life is 26 months 



Consult your doctor before taking this medicine, if you: 


Experience unexplained shortness of breath, cough, and fever that comes on suddenly. These could be symptoms of a serious lung condition. 

Have severe or continuing diarrhea that lasts up to 14 days. 

Experiencing adverse skin reactions like blistering, peeling, or loosening of the skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin  


Side effects 

         Common side effects 

  • Diarrhea 

  • Fever 

  • Allergic skin reaction 

  • Nausea and Vomiting 

  • Increase in liver enzyme levels 

  • Eye irritation 

  • Difficulty in breathing 

  • Abdominal pain 

  • Sore throat 

  • Redness around fingernails 

Serious side effects 

 Unusual bleeding (in cough and urine),eye irritation or pain, or swelling of the ankles or feet 


Missed dose 

If patient miss a dose of medicine, skip it and continue with the normal schedule. No need to double the dose 


Get the emergency medical treatment and contact your physician  


Which disease area  
non-small cell lung cancer (NSCLC)  
Precaution Usage 
 Which disease area  
non-small cell lung cancer (NSCLC)  


General warning and precautions 

Do not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after administering gefitero. 

Diarrhea can occur as a side effect. Drink plenty of fluids and inform the doctor in case if it doesn't stop or there is blood in stools. 


It is usually taken on an empty stomach once a day, at least 1 hour before or 2 hours after eating a meal or snack. Take gefitero at around the same time every day.


Gefimipsa 250MG CAPSULE-  Ark Life Sciences Pvt Ltd 

Geficad 250mg Tablet-  Cadila Pharmaceuticals Ltd 

Geftinat 250Mg Tablet-  Natco Pharma Ltd 

Geffon 250Mg Tablet-  Zydus Cadila 

Chemogef 250Mg Tablet- Neon Laboratories Ltd 

Geftistar 250mg Tablet-  Lupin Ltd 

Alternate brands 

Debrit 250 mg Tablet - Pfizer Ltd. 

Gefitrust 250 mg Tablet - Panacea Biotec Ltd. 

Geftinat 250 mg Tablet - Natco Pharma Ltd. 

Geftistar 250 mg Tablet- Lupin Ltd. 

Grexam 250 mg Tablet- Ranbaxy Laboratories Ltd. 


Q What is Gafitero 

Gefitero 250 mg Tablet is an anticancer medicine used for the treatment of cancer of the lungs. Take the medicine under the supervision of a qualified physician. This medicine is not recommended for use in patients with lung and liver diseases 

Q How Gafitero works 

Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that regulate their growth. This medicine works by binding the chemical messenger, EGFR, thus inhibits the cancer signaling pathways. This is how the medicine inhibit further growth of the cancer cells. 

Q What are the side effects 

Side Effects of Gafitero include nausea, rash, vomiting and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult the doctor if it happens. It makes the patient sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. 

Q In what strength it is available 

It is available in 250mg 

Q What should I avoid while receiving this medicine 

Avoid grape juice and smoking while taking the medication 

Q How to use Gifitero 

Gifitero 250mg Tablet is a pill to be administered orally, once a day without food as prescribed by the concerned specialist. Take Gifitero 250 mg Tablet empty stomach, at least 1 hour before or 2 house after meals. Take it the same time each day so that you remember when to take it 

Q What happens when I miss a dose 

If you miss a dose of medicine, skip it and continue with the normal schedule. No need to double the dose 

Q Does this medicine effects liver function 

There is no data available. Consult doctor before consuming the medicine. 

Q Can I drive after taking this medicine 

Do not drive if you have any symptoms that affect your ability to concentrate and react. Gefitero Tablet make you feel weak. This may affect your driving ability. 

Q Can I take this medicine during pregnancy 

Gefitero tablet is not safe to use during pregnancy as there is proven evidence of risk to the developing baby.  

Q Can I take this medicine during breast-feeding 

Gefitero tablet is probably not safe to use during breastfeeding. 

Q Can I consume alcohol while taking this medicine 

It is not safe to consume Alcohol 

Q Does it affect kidney functions 

There are no affects on the kidney functions 

Q What are the storage conditions 

Store the medicine at room temperature (10-30°C) 


Medicine interaction 

  • Warfarin 

  • Ranitidine, cimetidine, famotidine, omeprazole, lansoprazole, rabeprazole) 

  • Vinorelbine 

  • NSAIDs (such as ibuprofen, naproxen), corticosteroids           

Disease interaction 

The drug is contraindicated in patients who have suffered or are suffering from glaucoma, cardiac disorders, lungs or liver disorders or renal malfunctioning.. 

         Alcohol interaction 

Alcohol may cause interactions, consult your doctor  

         Food interaction 

The patient should also avoid grapefruit and grapefruit juice while taking the medicine. Take with or without food. The absorption is unaffected by food. 




  • Gefitinib: Drugs information and usage are available at: - https://go.drugbank.com/drugs/DB00317 and https://pubchem.ncbi.nlm.nih.gov/compound/Gefitinib.

Gefitinib: Mechanism, side effects, and dosage are available at: - https://my.clevelandclinic.org/health/drugs/20300-gefitinib-tablets, https://www.cancerresearchuk.org/about-cancer/treatment/drugs/gefitinib, and https://www.webmd.com/drugs/2/drug-75201/gefitinib-oral/details

Above Content has been reviewed by Professionals