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GLIVEC 400MG TABLET

Mfd. by :- Novartis (Fulfilled By : Magicine Pharma)

Glivec 400mg Tablet

SAFE AND SECURE


Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Brand name – Glivec

Generic name – Imatinib

Manufacturer – Novartis

Strength – 400mg

Dosage Form – Tablet

Composition – Imatinib

Indication – Blood Cancer

Storage – at 30°C

Overview of Glivec 400mg tablet

Glivec 400mg tablet is a chemotherapy medication that is used in the treatment of several blood cancers (leukemia) like myelodysplastic disorder. It is also used to treat gastrointestinal tumours. The generic name of this medication is Imatinib. It is a tyrosine kinase inhibitor that shows antineoplastic activities. It is a strictly prescription-based medication.

Pharmacodynamics

Glivec is a 2-phenylaminopyrimidine derivative which is a tyrosine kinase inhibitor. It inhibits the working of kinase, especially BCR-ABL protein. This protein is responsible for the progression of cancer. Glivec shows antineoplastic properties that is it stops the cell growth and spreading of the cancer cells.

SIDE EFFECTS

  • Diarrhea
  • Vomiting
  • Nausea
  • Loss of appetite
  • Dizziness
  • Extreme fatigue 
  • Blurred vision
  • Irregular heart rate
  • Chest pain
  • Muscle cramps
  • Pink eye  
  • Redness and rashes
  • Swelling of joints
  • Trouble in sleeping
  • Hair loss
  • Shortness of breath
  • Yellowing of eye and skin
  • Pink mucous in the cough

Sudden weight loss or weight gain

DOSAGE

Glivec 400mg tablet is prescribed by the doctor hence, it is advisable to follow the prescription so is taken orally once or twice every day with a meal.

Missed dose

It is advisable to avoid missing any doses. In case you miss a dose of Glivec tablets consult your doctor immediately.

Overdose

In case of an overdose of Glivec 400mg, immediately contact your doctor or any healthcare provider and seek medical attention.

WARNINGS

  • Glivec 400mg can cause an allergic reaction in some patients so it becomes necessary to read the complete composition list and consult the doctor in case of any ingredient that induces allergies.
  • Inform the doctor about all the vitamin supplements, herbal medications, and prescription and non-prescription drugs since Glivec can react with them. 
  • It is advisable to avoid pregnancy during and till 14 days after the last dose since Glivec can cause harm to the fetus.
  • Also, avoid breastfeeding till one month after the last dose of Glivec.
  • Avoiding alcohol consumption and operating heavy machinery is advisable.

Inform the doctor about past medical conditions – thyroid conditions, lung, kidney, and liver complications.

Q - What is Glivec?

Ans – Glivec is an anticancer tablet that is primarily used in the treatment of blood cancer.

Q - How can I take Glivec?

Ans –Glivec tablets are taken orally once or twice every day.

Q – From where can I purchase Glivec 400mg tablets?

Ans – Purchase Glivec 400mg tablets from Magicine Pharma.

Q - Where to store Glivec tablets?

Ans - It is advisable to store Glivec tablets at a place below 30°C.

Q - Can I drink alcohol with Glivec?

Ans - Avoid drinking alcohol during the treatment with Glivec 400mg even though no interactions of both are known.

Q - How long is the treatment with Glivec?

Ans - The doctor decides for how long the treatment with Glivec will continue depending on the condition, stage, and health of the patient.

Q - Can I drive after consuming Glivec?

Ans - It is advisable to avoid driving and operating heavy machinery as Glivec 400mg causes dizziness as one of the side effects.

Q - Is it safe to take Glivec during pregnancy?

Ans – Glivec can cause harm to the fetus hence it is advisable to avoid the pregnancy or consult the doctor for the same.

Q - What is the strength of Glivec?

Ans – Glivec is available in the form of 400mg capsules.

REVIEW

Interactions

With medicines

Glivec can interact with some other prescription and non-prescription medicines and interfere with their workings hence inform the doctor if taking the following –

  • Adalimumab
  • Carbamazepine
  • Enzalutamide
  • Fentanyl
  • Ibrutinib
  • Olaparib
  • Rifampin
  • Warfarin

With disease

Glivec can interact with some diseases so it is advisable to inform the doctor if suffering from-

  • Cardiovascular disorder
  • Liver complications
  • Kidney complications
  • Gastrointestinal disorders
  • Hyperthyroidism

With alcohol

Interactions of alcohol with Glivec 400mg are unknown although it is still advisable to avoid alcohol consumption during the treatment.

Contraindication

Glivec 400mg tablets should not be consumed by patients who show allergic reactions to them.

Alternate Brands

  • Veenat
  • Imatikast
  • Imatero
  • Imat
  • Levin

Reference

Imatinib: Uses, interactions, mechanism of action | DrugBank Online.DrugBank. https://go.drugbank.com/drugs/DB00619

Imatinib: MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a606018.html

Imatinib Drug Interactions CheckerDrugs.com. https://www.drugs.com/drug-interactions/imatinib-index.html?filter=3

Above Content has been reviewed by Professionals