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mylan
30 tablet
Tenofovir Alafenamide
Keep in cold place
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Overview
Hepbest tablet, comprising Tenofovir Alafenamide 25mg, is an antiviral medicine. It is prescribed for the treatment of HIV (Human Immunodeficiency Virus) infection and chronic Hepatitis B Virus (HBV) infection. It works to slow or stop the multiplication of the virus in the body and helps to clear the infection. It is advisable to take this medicine exactly as prescribed by the healthcare provider for better efficacy without increasing or decreasing the dose strength. This medicine is available at the best price in India.
HIV infection and Hepatitis B Virus infection
HIV infection and Hepatitis B Virus infection
The following are the possible side effects that can occur during your treatment with HEPBEST 25mg Tablet. Contact your medical practitioner immediately if any of the above-mentioned side effects appear.
Headache
Fever
Diarrhea
Vomiting
Nausea
Skin rash
Itching
Chills
Dizziness
Hepbest (Tenofovir Alafenamide 25mg) tablet is available in the strength of 25 mg in the form of tablets for oral administration. It is a prescription medicine that helps to slow down the multiplication of the virus in the body. However, this medicine is not a permanent cure for HIV. it is advisable to not skip a dose, or change the dose strength. Swallow the tablet as a whole with water, without breaking, cutting, or chewing it.
HEPBEST 25mg Tablet is an antiviral drug. It is a phosphonamidate prodrug of tenofovir (2’-deoxyadenosine monophosphate analog). It enters primary hepatocytes by passive diffusion and by the hepatic uptake transporters OATP1B1 and OATP1B3. It is converted to Tenofovir through hydrolysis primarily by carboxylesterase 1 (CES1) in primary hepatocytes. Tenofovir is phosphorylated by cellular kinases to the pharmacologically active metabolite Tenofovir Diphosphate. Tenofovir Diphosphate works to inhibit HBV replication through incorporation into viral DNA by the HBV reverse transcriptase, which results in DNA chain termination.
Alcohol
unsafe
Do not consume alcohol while taking Tenofovir Alafenamide 25mg Tablet
Pregnancy
consult your doctor
Do not take Tenofovir Alafenamide 25mg Tablet without consulting the doctor, in case of pregnancy.
Breast Feeding
consult your doctor
Do not take Tenofovir Alafenamide 25mg Tablet if you're breastfeeding. Consultation of the doctor is advised.
Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of Tenofovir Alafenamide 25mg Tablet.
Kidney
precaution
Do not take Tenofovir Alafenamide 25mg Tablet without a doctor's consultation in case of kidney problems.
Liver
precaution
Share your medical history with the doctor in case of liver disease before taking Tenofovir Alafenamide 25mg Tablet.
It is advisable to not skip a dose. If you miss a dose, make sure to take it as soon as you remember. However, if it is already time for your next scheduled dose, skip the missed dose and take the scheduled dose. Also, make sure to not increase the dose strength to catch up with the missed dose.
Hepbest 25mg tablet is a prescription medicine. It is used in the treatment of HIV (Human Immunodeficiency Virus) infection and chronic Hepatitis B Virus (HBV) infection.
No, it is not a habit-forming medicine.
Avoid the consumption of alcohol.
The side effects of Hepbest 25mg tablet are headache, fever, diarrhea, vomiting, nausea, skin rash, itching, etc. There can also be other side effects. Make sure to consult your healthcare provider if side effects occur or last longer than usual.
Take this medicine exactly as prescribed by the healthcare provider for better efficacy without increasing or decreasing the dose strength. Swallow the tablet as a whole with water, without breaking, cutting, or chewing it.
Take the Hepbest 25mg tablet as soon as you remember to do so. On the other hand, skip the missed dose and resume your usual routine if your next dose is almost due. Avoid taking two doses at once.
Zhao, J., Wu, L., Yang, X., Gao, Z., & Deng, H. (2024). Renal function changes in chronic hepatitis B patients. arXiv. https://arxiv.org/abs/2403.02361
Peng, W. T., Jiang, C., Yang, F. L., Zhou, N. Q., Chen, K. Y., Liu, J. Q., Peng, S. F., & Fu, L. (2023). Tenofovir alafenamide versus entecavir for treating hepatitis B virus‑related acute‑on‑chronic liver failure: A real‑world study. Frontiers in Microbiology, 14, Article 1185492. https://doi.org/10.3389/fmicb.2023.1185492.
Li, Y., Li, Y. W., & Gao, Y. (2025). Effect of entecavir, tenofovir disoproxil fumarate, and tenofovir alafenamide antiviral therapy on renal function in chronic hepatitis B patients: A real‑world retrospective study. International Journal of General Medicine, 18, 1143–1153. https://doi.org/10.2147/IJGM.S497550.
Suda, G., & colleagues. (2023). Prophylactic tenofovir alafenamide for hepatitis B virus reactivation and reactivation‑related hepatitis. Journal of Medical Virology. Advance online publication. https://doi.org/10.1002/jmv.28452
Chen, A.‑Z., Kang, W., Li, Z.‑H., Chen, D.‑Y., Huang, Q.‑H., & Xu, Q. (2023). Efficacy and safety of tenofovir alafenamide in patients with chronic hepatitis B exhibiting suboptimal response to entecavir. World Journal of Gastrointestinal Surgery, 11(34), 8139–8148. https://doi.org/10.3748/wjg.v29.i34.5907
