HEPCVEL

Mfd. by :- Cipla Ltd (Fulfilled By : Magicine Pharma)

hepcvel

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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PACKAGE

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Medicine details

Brand name - Hepcvel
Generic name - Sofosbuvir-Velpatasvir
Manufacturer - Cipla Ltd
Salt composition - Sofosbuvir (400mg) + Velpatasvir (100mg)
Storage - Store at room temperature (10-30°C)
Dosage form - Oral (tablet)
Strength - 400mg + 100 mg
Packaging - Bottle of 28 tablets
Gender - Unisex
Prescription required - Yes
Indication - Used in the treatment of Hepatitis C Virus infection

Description

Hepcvel (Sofosbuvir-Velpatasvir) tablet is used in the treatment of chronic Hepatitis C Virus (HCV) infection in adults. It works by lowering the multiplication of HCV in the body, and thereby removing the virus from the body. The active ingredient of Hepcvel, Sofosbuvir-Velpatasvir is the combination of two direct acting agents against the virus (HCV).

Pharmacodynamics

Hepcvel Tablets are an oral fixed-dose combination (FDC) of sofosbuvir and velpatasvir which are direct-acting antiviral agents against the hepatitis C virus (HCV). Sofosbuvir is a nucleotide analog HCV NS5B polymerase inhibitor and velpatasvir is an NS5A inhibitor. The effect of Sofosbuvir 400 mg (recommended dosage) and 1200 mg (three times the recommended dosage) on QTc interval was evaluated in an active-controlled (moxifloxacin 400 mg) thorough QT trial. At a dose (three times the recommended dose), Sofosbuvir does not prolong QTc to any clinically relevant extent.The effect of Velpatasvir 500 mg (five times the recommended dosage) was evaluated in an active-controlled (moxifloxacin 400 mg) thorough QT trial. At a dose (five times the recommended dose), Velpatasvir does not prolong QTc interval to any clinically relevant extent.

Ingredients

The active ingredient of Hepcvel is Sofosbuvir-Velpatasvir.

Usage of medicine

Hepcvel tablet is used in the treatment of chronic Hepatitis C Virus (HCV) infection in adults.

Alternate brands

  • Velpanat tablet

  • Velasof tablet

  • Veplaclear tablet

  • Sofocure-v tablet

Side-effects

Common side-effects

  • Tiredness

  • Cough

  • Headache

  • Skin rash

  • Diarrhea

  • Loss of appetite

  • Muscle pain

  • Cramps

  • Lower back pain

  • Irritability

  • Nausea 

Serious side-effects

  • Anemia 

  • Difficulty in breathing

  • Fainting

  • Chills 

Dosage

Normal dose

Take Hepcvel tablet exactly as your healthcare provider tells you. Do not increase or decrease the dose strength, unless your healthcare provider tells you.

Missed dose

If you miss a dose, take the dose as soon as you remember. But, if it is already the time for the next dose, skip the missed dose. Do not double the dose in order to catch up.

Overdose

It is advised to seek medical help in case of overdose.

 

Warning and precautions

  • Hepcvel tablet is not recommended for consumption in children.

  • Make sure to tell your healthcare provider regarding your medical history and all the medicines you already take.

  • Do not alter or increase the dose strength on your own,  unless your doctor tells you.

  • Do not crush, chew or break Hepcvel tablet.

  • Do not stop taking this medicine as per your own wish.

  • Consult your doctor in case of any problematic side effect.

  • In patients with kidney disease, Hepcvel should be administered the utmost caution.

  • In patients with liver disease, Hepcvel is safe, only if prescribed.

  • During pregnancy, make sure to consult your healthcare provider before taking Hepcvel tablet.

  • During breastfeeding, Hepcvel is safe if prescribed by the healthcare provider.

  • Avoid the consumption of alcohol.

  • Do not drive or operate heavy machines if you experience side effects like dizziness or loss of vision (or any other).

FAQs

Q1- What is Hepcvel?

A- Hepcvel tablet is used in the treatment of chronic Hepatitis C Virus (HCV) infection in adults.

Q2- In what strength is it available?

A- It is available in the strength of 400mg + 100 mg.

Q3- What are the storage conditions for Hepcvel?

A- Store at room temperature (10-30°C). Keep it away from children, direct heat or light and moisture.

Q4- Can I consume alcohol with this medicine?

A- Avoid consuming alcohol. 

Q5- What should I avoid while consuming this medicine?

A- Avoid consumption of sugary foods.

Q6- Can I drive after taking this medicine?

A- Do not drive or operate machinery, if you feel dizzy after taking this medicine.

Q7- Can I take this medicine in liver disease?

A- Before taking this medicine, make sure to contact your healthcare provider.

Q8- Can I take this medicine in kidney disease?

A- In patients with kidney disease, Hepcvel should be administered with caution.

Q9 - What are the self care tips?

A- Keep yourself hydrated.

Q10- Can I take Hepcvel during pregnancy?

A- Hepcvel is safe during pregnancy, only if prescribed.

Q11- Can I take Hepcvel during breastfeeding?

A- Hepcvel is safe during breastfeeding, only if prescribed.

Q12- Is it a habit forming medicine?

A- No. it is not a habit forming medicine.

 

Above Content has been reviewed by Professionals