IMARECH

Mfd. by :- Arechar Healthcare (Fulfilled By : Magicine Pharma)

Imarech

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Imarech 

Generic Name: Imatinib mesylate 

Manufacturer: Arechar 

Dosage Form: Tablet  

Strength: 400mg 

Composition: Imatinib mesylate 

Indication: Blood cancer  

Storage: Store at room temperature  

Overview 

Imarech contains Imatinib mesylate as an active ingredient and this tablet belongs to a class of medication known as tyrosine kinase inhibitors. This medication is used for the treatment of a type of blood cancer known as CML (chronic myeloid leukemia) ALL (Acute lymphocytic leukemia) and gastrointestinal stromal tumor. Imarech tablet inhibits the proliferation and induces apoptosis (planned cell death) in BCR-ABL positive cells (cancer cells). Do not stop the dosage of Imarech tablets without taking permission from your physician.  

Pharmacodynamics  

Imatinib is an antineoplastic agent and a protein-tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine kinase, and it works as a specific inhibitor of several tyrosine kinase enzymes. Chronic myelogenous leukemia is associated with the Philadelphia chromosome promoting the generation of BCR-ABL (mutation, which results from the combination of two genes, known as BCR and ABL). BCR-ABL generates a fusion protein that acts as a constitutively active tyrosine kinase and imatinib works to inhibit this constitutive enzymatic activity. 

Usage  

Imarech (Imatinib mesylate) is used to treat certain types of cancers of blood cells and it works by preventing the multiplication and division of cancer cells. Do not perform activities that require attention and concentration, and get plenty of rest during the course of this medication to avoid side effects like dizziness and drowsiness. Dosage may vary differently to the patients according to their age, weight, and other health concerns. Do not discontinue the dosage of Imarech tablets without consulting with your healthcare professional.  

Interactions  

Imarech tablets may interact with other drugs and diseases. It is important to know about the interactions to prevent some unusual effects of this medication.  

Medicine Interactions  

  • Apalutamide  

  • Mitotane  

  • Baricitinib 

  • Colchicine  

  • Warfarin  

  • Pimozide  

  • Etanercept  

Disease Interactions  

  • Cardiovascular disease 

  • Liver impairment  

  • Fluid retention  

  • Bone marrow suppression 

  • Kidney impairment  

Alcohol Interaction  

  • Consuming alcohol during treatment with Imarech (Imatinib mesylate) tablets may lead to some unwanted risks and side effects. It is advisable to consult your physician or medical practitioner before consuming alcohol.  

Contraindications 

  • Imarech tablet is not recommended in patients having a known allergy to Imatinib mesylate or any other active ingredient present in this medication. 

  • Not recommended for use in patients known to be hypersensitive.  

Alternate

 

Side effects  

Imarech tablets may cause certain side effects. Discuss the benefits and risks with your medical practitioner; your physician will guide you according to your current state.  

Allergic Reactions 

  • Difficulty in breathing  

  • Pale skin 

  • Irregular heartbeat  

  • Unusual bleeding  

  • Bloody stool  

  • Swelling around the eyes  

  • Bloating  

  • Presence of blood in cough  

  • Fatigue  

Common side effects  

  • Blurred vision  

  • Indigestion  

  • Dizziness  

  • Weight loss  

  • Diarrhea  

  • Nausea  

  • Itching  

  • Joint pain 

  • Abdominal pain  

  • Joint pain  

  • Headache  

  • Weight gain  

  • Insomnia  

  • Seizures  

  • Anxiety  

  • Vomiting  

  • Muscle pain  

  • Heartburn  

  • Constipation  

Note - consult your pharmacist or healthcare professional if any possible side effects occur.  

Dosage  

Take the Imarech tablet exactly as prescribed by your physician. Do not crush, chew or break the tablet. Be sure to avoid skipping a dose.  

Missed Dose  

If you miss a dose of Imarech tablet consult a medical practitioner. Do not increase or decrease the strength of your dosage.  

Overdose 

In case of an overdose of the Imarech (Imatinib mesylate), be sure to consult a healthcare professional or a medical helpline for proper monitoring.

Warnings and precautions  

Before starting the course of Imarech (Imatinib mesylate) tablet, make sure to go through the warning and precautions mentioned below:-  

  • Use effective methods of contraception to prevent pregnancy while taking Imarech tablets.  

  • Imarech tablets are safe for use in children and adolescents with CML.  

For Females 

  • Do not take Imarech (Imatinib mesylate) tablet if you are pregnant or planning to become pregnant.  

  • Imarech tablets are not recommended in breastfeeding. Discuss all the risks and benefits with your healthcare professional or medical practitioner.  

General Precautions  

  • Close monitoring of thyroid hormone is required in some patients.  

  • Extreme caution is required in patients suffering from heart and blood vessel disorder.  

  • In children, close monitoring of growth parameters is required during treatment with Imarech (Imatinib mesylate). 

  • Use of an Imarech tablet may weaken your immune system and make you prone to infections.  

  • Inform your healthcare provider if you experience side effects like dizziness and blurred vision.  

Cautions  

  • Do not operate heavy machinery  

  • Do not crush or break the tablet 

  • Do not overdose  

  • Do not increase or decrease the dose strength.  

Q1. What is Imarech (Imatinib mesylate)? 

Ans. This tablet is used in the treatment of blood cancer (Chronic myeloid leukemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor.  

Q2. In what strength is it available? 

Ans. Imarech (Imatinib mesylate) tablets are available in the strength of 400mg. 

Q3. What are the side effects of Imarech? 

Ans. Some common side effects are - insomnia, difficulty in breathing, seizures, diarrhea, joint pain, constipation, anxiety, fatigue, edema, muscle cramp, etc.  

Q4. How can I take Imarech (Imatinib mesylate)? 

Ans. Take Imarech tablets as prescribed by your healthcare professional or medical practitioner.  

Q5. Can I take Imarech tables during pregnancy? 

Ans. This medication is not indicated for use during pregnancy 

Q6. What happens if I miss a dose of Imarech (Imatinib mesylate)? 

Ans. If you miss a dose of Imarech tablet, be sure to contact your healthcare professional to get the needed guidance. Do not increase the strength of the dose to cope with the skipped dose.  

Q7. Is it safe to drive after taking an Imarech tablet? 

Ans. Imarech tablets may affect your vision. Do not drive if such symptoms occur.  

Q8.  Can I take Imarech tablets in liver impairment? 

Ans. If you are suffering from liver impairment, do not administer Imarech tablets without discussing their risks with your doctor.  

Q9. Can I take Imarech (Imatinib mesylate) during breastfeeding? 

Ans. This medication is not indicated for use during breastfeeding. 

Q10.  Can I drink alcohol while taking Imarech tablets?  

Ans. It is not known whether Imarech interacts with alcohol or not. Consult a qualified medical practitioner before consuming alcohol with this medicine.  

Above Content has been reviewed by Professionals