IMATIB

Mfd. by :- Cipla (Fulfilled By : Magicine Pharma)

Imatib

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Imatib

Generic Name: Imatinib mesylate

Manufacturer: Cipla

Dosage Form: Tablets

Strength: 100mg and 400mg

Composition: Imatinib mesylate

Indication: Blood cancer

Packaging: 10 tablets in a strip

Storage: Store at room temperature

OVERVIEW

Imatib (Imatinib mesylate) tablet is used in the treatment of blood cancer. This medicine belongs

to a class of drugs known as tyrosine kinase inhibitors. The Imatib tablet works by stopping the

growth of cancer cells and also prevents the multiplication of cancerous cells. It is important to

take this medicine as prescribed by your doctor. The recommended dose of Imatib tablet is

decided by a doctor according to your previous medical condition and response to the

treatment. Regular monitoring of blood cell count and liver function is required while having

treatment with this medicine. Do not stop the use of Imatib tablets without consulting with your

doctor. If you experience any signs and symptoms while receiving this medicine, inform your

doctor immediately.

Pharmacodynamics

Imatinib Mesylate is a protein-tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine

kinase, the constitutive abnormal tyrosine kinase created by the Philadelphia chromosome

abnormality in CML. It inhibits proliferation and induces apoptosis in BCR-ABL positive cell lines

as well as fresh leukemic cells from Philadelphia chromosome-positive chronic myeloid

leukemia.

Interactions

Imatib tablets can interact with other medications and it may increase the risk for side effects.

Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interactions

● Baricitinib

● Carbamazepine

● Warfarin

● Pimozide

● Etanercept

● Leflunomide

Disease Interactions

● Bone marrow suppression

● Fluid retention

● Liver impairment

● Cardiovascular disease

● Kidney impairment

Alcohol Interaction

● Interaction with alcohol is unknown. Please consult your doctor before consuming

alcohol.

Contraindications

● Do not take this medicine if you are allergic to Imatinib mesylate.

● Imatib (Imatinib mesylate) medicine is not recommended in patients known to be

hypersensitive.

Side effects

This medicine may cause some common and serious side effects. Discuss the risks and

benefits of the Imatib tablets with the doctor before starting the treatment.

Common side effects

● Nausea

● Diarrhea

● Abdominal pain

● Joint pain

● Headache

● Weight gain

● Insomnia

● Vomiting

● Muscle pain

● Heartburn

● Indigestion

● Rash

● Bleeding

● Mouth ulcers

● Constipation

● Blurred vision

● Indigestion

● Dizziness

● Weight loss

● Change in taste

● Joint pain

Serious side effects

● Difficulty in breathing

● Irregular heartbeat

● Swelling around the eyes

● Pale skin

● Unusual bleeding

● Bloody stool

● Swelling of the hands and feet

● Bloating

● Presence of blood in cough

● Fatigue

Note - Immediately contact your doctor or medical practitioner if any side effects occur

Dosage

Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing

schedule.

Missed dose

● It is advisable not to miss a dose. If you miss a scheduled dose of Imatib tablets, contact

your doctor immediately.

Overdose

● In case of an overdose of Imatib tablets, the doctor will provide emergency medical

treatment.

Usage

This medication is used in the treatment of chronic myeloid leukemia and Acute lymphocytic

leukemia and gastrointestinal stromal tumor. Imatib tablets help to stop the growth of cancer

cells in the body. Take this medicine orally once a day with food. Do not take this medicine in

the wrong way as it may lead to some severe side effects. Avoid the consumption of alcohol. It

may increase the risk of dizziness. Keep yourself hydrated and maintain good nutrition while

having treatment with this medicine. Avoid eating grapefruit and drinking grapefruit juice.

Warnings

Before starting treatment with Imatib medicine, please inform your doctor about your previous

medical history. If you experience any signs and symptoms while receiving this medication, do

not ignore those symptoms because it may lead to higher risk.

● Contraception

○ Use suitable methods of contraception to prevent pregnancy while taking this

medicine.

● Children and adolescents

○ Imatib tablets are advisable for use in children and adolescents with CML.

Warnings for female

● Pregnancy

○ Do not use Imatib medicine if you are planning to become pregnant. Avoid this

medication at the time of pregnancy.

● Breastfeeding

○ This medicine is not recommended in breastfeeding unless it is required. Please

consult with your doctor before starting treatment with this medication.

Precautions

● Close monitoring of thyroid hormones is required in patients suffering from

hypothyroidism.

● Imatib tablets may interact with other medications and cause some severe side effects.

● This medicine should be used with caution in patients who are suffering from heart

disease.

● In children, close monitoring of growth parameters is required during treatment with this

medicine.

● Inform your doctor if you experience any side effects like - nausea, abdominal pain,

difficulty in breathing, irregular heartbeat, and fatigue.

● This medicine may increase the risk of getting infections.

Cautions

● Do not drive or operate heavy machinery.

● Do not crush or break the tablet.

● Not safe for pregnant women.

● Do not breastfeed while receiving this medication.

Substitutes

● Imat

● Mitinib

● Imanib

● Levin

Q1. What is Imatib (Imatinib mesylate)?

Ans. This medicine is used in the treatment of blood cancer. It belongs to a class of drugs

known as tyrosine kinase inhibitors. Imatib tablets help to stop the growth of cancer cells in the

body.

Q2. What are the side effects?

Ans. Some common side effects are - vomiting, joint pain, weight gain, irregular heartbeat, pale

skin, headache, etc.

Q3. In what strength is it available?

Ans. This medicine is available in the strength of 100mg and 400mg.

Q4. Can I consume alcohol while receiving this medicine?

Ans. Please consult your doctor before consuming alcohol.

Q5. What happens if I miss a dose?

Ans. If you miss a scheduled dose of Imatib tablets, contact your doctor immediately.

Q6. How to take this medicine?

Ans. It is important to take this medicine as prescribed by your doctor.

Q7. How does Imatib tablet work?

Ans. It works by stopping the growth of cancer cells and also prevents the multiplication of

cancerous cells.

Q8. Can I take this medicine during pregnancy?

Ans. This medicine is not recommended during pregnancy.

Q9. Does this medicine affect kidney function?

Ans. Please consult your doctor before consuming this drug.

Q10. What should I avoid while receiving this medication?

Ans. Avoid contact with people who have infections and avoid eating grapefruits.

Q11. Can I take this medicine during breastfeeding?

Ans. This medicine is not recommended in breastfeeding unless it is necessary.

Q12. Does this medicine affect liver function?

Ans. Please consult your doctor before consuming this drug.

Q13. What are the storage conditions?

Ans. Store this medicine at room temperature.

Above Content has been reviewed by Professionals