Mfd. by :- Novartis (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand Name:- Mekinist
Generic Name:- Trametinib
Manufacturer:- Novartis
Dosage Form:- Tablet
Strength:- 0.5mg
Composition:- Trametinib
Packaging:- 30 tablets
Indication:- Skin Cancer
Storage:- Store at room temperature
Mekinist (Trametinib) is used in the treatment of metastatic melanoma (skin cancer that has spread to other areas of the body). This medicine comes in the form of tablets. This medicine has to be taken orally. This medication works by slowing the growth of cancer cells. Do not take this medicine in the wrong way as it may lead to some severe side effects. Take this medicine according to your doctor’s dosing schedule. It is advisable not to change or stop the dose without taking suggestions from the doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately. Protect this medicine from heat and light.
Trametinib is a reversible inhibitor of the mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 activation and MEK1 and MEK2 kinase activity. After the oral administration of Trametinib, the effect of this medicine can be absorbed in 1.5 hours.
This medication may cause some unwanted side effects. Immediate medical attention is required otherwise it can also lead to higher risk. Discuss the risks and benefits of this medication with your medical advisor before starting the treatment.
Diarrhea
Bleeding
Nausea
Vomiting
Bloating
Coughing up blood
Dizziness
Lightheadedness
High blood pressure.
Abdominal pain
Shortness of breath
Allergic reaction
Swelling
Itching
Chest pain
Dry skin
Weakness
Weight gain
Nose bleeds
Constipation
Dry mouth
Dehydration
Anemia
Irregular heartbeat
Back pain
Fever
Blurred vision
Hair loss
Cough
Pounding in the ears
Note- contact your doctor, if any side effects occur
Take this medicine as prescribed by your doctor. Do not crush or chew. Take this medicine on an empty stomach. Take this medicine one hour before or two hours after the meals.
It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately.
In case of an overdose, the doctor will provide emergency medical treatment.
Mekinist (Trametinib) is a cancer medicine. This medicine interferes with the growth and spread and cancer cells in the body. It is also used in combination with another medicine to treat thyroid cancer and non-small cell lung cancer. Take this medicine on an empty stomach one hour before or two hours after the meals. Take this medication at the same time of the day to get the most benefits from it. Your doctor will set your dosing schedule according to your medical conditions and response to the treatment. Do not stop the use of this medicine without taking permission from your doctor. Take this medicine as prescribed by your medical advisor. Try not to miss your regular dosing schedule. Do not use this medicine if you are pregnant.
Before starting treatment with the Mekinist tablet, do not forget to discuss your previous medical history with your doctor.
Contraception
Use effective methods of contraception to prevent pregnancy while taking this medicine.
Children and adolescents
This medicine is not advisable for use in children and adolescents.
Pregnancy
Mekinist tablets shouldn’t be used by women who are pregnant. It is recommended that this medication should be avoided during pregnancy.
Breastfeeding
This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication.
This medicine may increase the risk of bleeding.
Trametinib medication increases the risk of developing blood clots.
Skin problems can occur such as- rash, irritation, and skin ulcers that may become infected
Regular monitoring of blood pressure is required while receiving treatment with Mekinist.
If you have a history of heart disease. Do not take this medicine without taking permission from your doctor
This medicine may increase blood sugar levels.
This medication increases the risk of eye problems like- vision change and pain in the eyes.
Do not crush, chew, or break the tablet.
Not safe for pregnant women
Do not drive or operate heavy machinery.
Do not breastfeed while receiving this medication.
Ans. Mekinist (Trametinib) is used in the treatment of metastatic myeloma (skin cancer that has spread to other areas of the body). This medicine is also used in combination with other medications to treat thyroid cancer and non-small cell lung cancer.
Ans. Trametinib medicine interferes with the growth and spread and cancer cells in the body. This medication works by slowing the growth of cancer cells.
Ans. It is available in the strength of 0.5mg and 2mg.
Ans. Some common side effects are:- nausea, constipation, diarrhea, bleeding, dizziness, high blood pressure, abdominal pain, shortness of breath, allergic reaction, etc.
Ans. Follow your doctor’s instructions about any restrictions on food and other activities.
Ans. Take this medicine on an empty stomach one hour before or two hours after the meals.
Ans. Get plenty of rest and maintain good nutrition.
Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol.
Ans. This medicine is not recommended in breastfeeding unless it is necessary.
Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately.
Ans. This medicine is not recommended for pregnant women.
Ans. Store this medicine at room temperature. Protect it from heat and light.
Ans. This medicine may cause dizziness. Do not drive if any symptoms occur.
Ans. Please consult your doctor before consuming this drug.
Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.
Dabrafenib
Idelalisib
Tucatinib
Erdaftinib
Enzalutamide
Midostaurin
Lung toxicity
Cardiomyopathy
Hepatic impairment
Ocular toxicities
Renal impairment
Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Mekinist medicine is not recommended for use in patients with known allergy to Trametinib.
This medicine is contracted in patients known to be hypersensitive.
Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.
Dabrafenib
Idelalisib
Tucatinib
Erdaftinib
Enzalutamide
Midostaurin
Lung toxicity
Cardiomyopathy
Hepatic impairment
Ocular toxicities
Renal impairment
Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Mekinist medicine is not recommended for use in patients with known allergy to Trametinib.
This medicine is contracted in patients known to be hypersensitive.