NAIVEX

Mfd. by :- Hetero (Fulfilled By : Magicine Pharma)

Naivex

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Naivex
Generic Name: Dolutegravir
Manufacturer: Hetero 
Dosage Form: Tablet
Strength: 50mg
Composition: Dolutegravir
Indication: HIV
Packaging: 30 tablet
Storage: Store at room temperature

Overview

Naivex (Dolutegravir) tablet is used in the treatment of HIV (Human immunodeficiency virus) infection. This medication helps to reduce the amount of HIV in your body and improves the quality of life. It works by blocking an enzyme called integrase and reduces the amount of HIV in the blood. Naivex tablet boosts your immune system to fight against infection and prevents the virus from multiplying. It is important to take this medicine as prescribed by your doctor. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor.

Pharmacodynamics 

Naivex, comprising Dolutegravir, is an HIV-1 antiviral agent. It works to inhibit HIV integrase and binds to the active site. It blocks the strand transfer step of retroviral DNA integration in the host cell. During the clinical trials, it was indicated that Dolutegravir has a tight binding and longer dissociative half-life. Therefore, it is indicated in combination with other antiretroviral agents for the treatment of patients with HIV-1 infection, provided their age is 12 or above and present weight is at least 40 kg.

Usage 

Naivex tablet contains Dolutegravir as an active ingredient. This medication is not a permanent cure for HIV infection. It only prevents the multiplication of HIV (human immunodeficiency virus) infection in human cells. The recommended dose of Naivex medicine is decided by a doctor according to your previous medical condition and response to the treatment. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately. Do not take this medicine in the wrong way as it may lead to some serious side effects.

Interactions 

Naivex tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interaction 

  • Aluminium Hydroxide

  • Efavirenz

  • Phenytoin

  • Metformin

  • Dofetilide

Alcohol Interaction

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.

Contraindication

  • Do not use this medicine if you are allergic to Dolutegravir. 

  • Naivex tablet is not recommended in patients known to be hypersensitive.

Side effects 

This medicine may cause some common side effects. Discuss the risks and benefits of the Naivex tablets with the doctor before starting the treatment.

Common side effects 

  • Headache

  • Insomnia

  • Dizziness

  • Nausea

  • Fatigue

  • Muscle pain

  • Skin rash

  • Itching

  • Fever

  • Chills

  • Sore throat

  • Mouth sores

  • Loss of appetite

  • Stomach ache

  • Difficulty in breathing

  • Muscle or joint pain

  • Yellowing of skin

  • Vomiting

  • Unusual tiredness

  • Swelling on face, hands, or legs

  • Dark-colored urine

  • Tightness in the chest

Note - immediately contact your health care provider if any side effects occur.

 

Dosage 

Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule. 

Missed dose 

  • It is advisable not to miss a dose. If you miss a scheduled dose of Naivex tablets, contact your doctor immediately. 

Overdose 

  • In case of an overdose of Naivex tablets, the doctor will provide emergency medical treatment.

Warnings 

Before starting treatment with Naivex medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk. 

  •  Contraception 

    • Use suitable methods of contraception to prevent pregnancy while taking Naivex medicine. 

  • Children and adolescents 

    • Naivex tablets are not recommended for use in children under the age of 12. 

Warnings for female 

  • Pregnancy

    • Do not use Naivex medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy. 

  • Breastfeeding

    • This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Naivex (Dolutegravir). 

 

Precautions 

  • Close monitoring of body fat distribution and body weight is required during treatment with this medicine. 

  • Naivex tablet may increase the risk of lactic acidosis. 

  • This medication may increase the risk of immune reconstitution syndrome.

  • Close monitoring of liver function is required during treatment with this medication. 

Cautions 

  • Do not drive or operate heavy machinery.

  • Do not crush or break the tablet. 

  • Not safe for pregnant women. 

  • Do not breastfeed while receiving this medication.

Q1. What is Naivex?

Ans. Naivex is an antiviral medication that prevents the human immunodeficiency virus (HIV) from multiplying in your body. Naivex tablet also helps to delay the production of HIV infection and improves the quality of life.

Q2.  What are the side effects?

Ans. Some common side effects are:- fatigue, sore throat, headache, nausea, taste change, stomach ache, diarrhea, fever, chills, blurred vision, weight loss, abnormal dreams, etc.

Q3. Can I drive after taking this medicine? 

Ans. Naivex tablet may decrease your ability to drive or affect your vision. Do not drive if any symptoms occur.

Q4. How to take this medicine?

Ans. It is important to take Naivex tablet as prescribed by your doctor. 

Q5. In what strength is it available? 

Ans. Naivex tablet is available in the strength of 50mg.

Q6. How does Naivex (Dolutegravir) work?

Ans. Naivex tablet is an HIV-1 antiviral operator. It works by blocking the action of an enzyme (integrase) and reduces the amount of HIV in the blood.

Q7. What happens if I miss a dose? 

Ans. If you miss a scheduled dose of this medicine, contact your healthcare provider immediately.

Q8. Can I consume alcohol while taking this medicine? 

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q9.   What should I avoid while receiving this medicine? 

Ans. Follow the advice of your doctor about any restrictions on food and other activities.

Q10. What are the self-care tips? 

Ans. Keep yourself hydrated and maintain good nutrition.

Q11. Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended during pregnancy.

Q12. What are the storage conditions?

Ans. Store this medicine at room temperature. Keep it away from direct heat and light. 

Q13. Does this medicine affect liver function? 

Ans. Please consult your doctor before consuming this drug.

 

Above Content has been reviewed by Professionals