Marketed By
pfizer
Pack of
10 Tablet in a strip
Salt Composition
Sirolimus
Storage
keep in cold place
Delivering To: —
All Substitutes
Indication
KIDNEY TRANSPLANT
Description
Rapamune 1mg tablet is a prescription-based medication that should be taken under a doctor's guidance. The medication is used to help prevent organ rejection in kidney transplantation. Its salt composition is Sirolimus. It acts as an immunosuppressant by inhibiting the mTOR pathway and reducing T cell activation and proliferation. It belongs to the group of mTOR inhibitors (immunosuppressive agents). Regular monitoring by the healthcare professional is necessary to ensure safe and effective treatment. The patient should follow the prescribed dose exactly and report any unusual symptoms or side effects immediately.
Uses
- Help to prevent organ rejection in patients with kidney transplantation
Side Effects
Every medication has several side effects that may vary from person to person and should be monitored by a healthcare professional. Common ones include:
- Fatigue or weakness
- Nausea and vomiting
- Rash
- Infrequent, absent, or heavy periods
- Rapid heart rate
- High blood sugar
- Joint pain
- Acne
- Swelling of the body, including feet and hands
- Headache
- Fever, pain
- High blood pressure and cholesterol levels
- Constipation, diarrhea, stomach pain
How To Use
Rapamune 1mg tablet should be taken with a whole glass of water with or without food at the same time every day. Do not self-administer as it can cause side effects. Always follow the recommended dosage and never adjust or skip doses without consultation with a healthcare professional, as this can increase the risk of organ rejection or other complications.
How It Works
After transplantation, the immune system sees the new organ as foreign and tries to attack it. Rapamune 1mg tablet weakens this immune response by inhibiting the activity and growth of immune cells that cause rejection. This helps the body accept and keep the transplanted organ working well.
Safety Advice
Alcohol
UNSAFE
Pregnancy
PRECAUTION
Breast Feeding
PRECAUTION
Driving
DANGER
Kidney
CONSULT YOUR DOCTOR
Liver
CONSULT YOUR DOCTOR
FAQs
Rapamune 1mg is used to prevent organ rejection after kidney transplantation by reducing the immune system's attacks on the new organ.
Rapamune is taken with or without food with a whole glass of water at the fixed time every day to enhance the effectiveness of the medication.
Avoid alcohol and limit it while taking Rapamune 1mg tablet, as it can increase the risk of liver problems and worsen the side effects.
Avoid sudden stopping, avoid alcohol, consult the doctor while using the medication, and regular blood tests are important.
Rapamune 1mg tablet active ingredient is Sirolimus, which works as an immunosuppressant by inhibiting the mTOR pathway, thereby preventing the T cell activation and reducing the risk of organ rejection.
References
- Basa-Dénes, O., Angi, R., Kárpáti, B., Jordán, T., Ötvös, Z., Erdősi, N., ... & Glavinas, H. (2019). Dose escalation study to assess the pharmacokinetic parameters of a nano-amorphous oral sirolimus formulation in healthy volunteers. European Journal of Drug Metabolism and Pharmacokinetics, 44(6), 777-785. https://pubmed.ncbi.nlm.nih.gov/31089971/
- Wyeth, T. M. (2017). Pr RAPAMUNE®. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021083s059,021110s076lbl.pdf
- Tejani, A., Alexander, S., Ettenger, R., Lerner, G., Zimmerman, J., Kohaut, E., & Briscoe, D. M. (2004). Safety and pharmacokinetics of ascending single doses of sirolimus (Rapamune®, rapamycin) in pediatric patients with stable chronic renal failure undergoing dialysis 1. Pediatric transplantation, 8(2), 151-160. https://pubmed.ncbi.nlm.nih.gov/15049795/
- Tao, C., Wen, X., Zhang, Q., & Song, H. (2019). Solid sirolimus self-microemulsifying drug delivery system: development and evaluation of tablets with sustained release property. Iranian Journal of Pharmaceutical Research: IJPR, 18(4), 1648. https://pmc.ncbi.nlm.nih.gov/articles/PMC7059041/
- Business, B. (2017). 7.7. 1 mTOR Inhibitors Rapamune®(Sirolimus) and AfinitorⓇ. Translating Molecules into Medicines: Cross-Functional Integration at the Drug Discovery-Development Interface, 25, 258.
Ratings And Reviews
3.75/5
4 Ratings
5 Star
25.00%
4 Star
25.00%
3 Star
50.00%
2 Star
0.00%
1 Star
0.00%
Shreya P.
Quality is outstanding
a year ago
Priya S.
Works fine
a year ago
View All Reviews
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MARKETER DETAILS
pfizer
DISCLAIMER
The contents of this website are for informative purposes only. They are not deliberated to be an alternative to any professional medical prescription and treatment. Seek the advice of a qualified health provider for questions regarding the medical condition. Do not ignore any professional medical advice because of something you have read on this website. This website offers links to other websites, thereby enabling you to go to the other website directly. Therefore, Magicine Pharma isn't responsible for the content of the links in the website or links in the linked websites. The links are provided to assist the visitors and are not approved by any professional health provider.

