SORANIB

Mfd. by :- Cipla (Fulfilled By : Magicine Pharma)

Soranib

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Soranib  

Generic Name: Sorafenib 

Manufacturer: Cipla  

Dosage Form: Tablet 

Strength: 200mg  

Composition: Sorafenib  

Packaging: 120 tablet (120 / bottle)  

Indication:  Kidney, Thyroid, and liver cancer 

Storage: Store at room temperature  

Overview 

Soranib (sorafenib) tablet is used to treat certain types of cancer (liver, kidney, and thyroid cancer). This medicine helps to prevent the multiplication of cancer cells. Tablet belongs to a class of medication known as a tyrosine kinase inhibitor. This is an anti-cancer medication that interferes with the growth and spread of cancerous cells. The recommended dose of medicine is decided by the doctor. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change or stop the dose without taking suggestions from your doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately. Do not crush or break the tablet.  

Pharmacodynamics  

Sorafenib is a kinase inhibitor that decreases tumor cell proliferation in vitro. Sorafenib inhibited tumor growth of HCC, RCC, and DTC human tumor xenografts in immunocompromised mice. Reductions in tumor angiogenesis were seen in models of HCC and RCC upon Soranib treatment, and increases in tumor apoptosis were observed in models of HCC, RCC, and DTC.  

After the oral administration, the effect of this medicine can be observed in 3 hours. 

Usage of soranib

This medicine is also used in the treatment of cancer that affects the cell of kidney and liver cells which can not be removed by surgical procedures. This medicine helps to stop the growth of cancerous cells. The dose is decided by a doctor according to your response to the treatment and your previous medical condition. Do not miss your regular dosing schedule. Consult your doctor immediately if you experience any symptoms during treatment with this medicine. This medication may take some time to show results. Store this medicine at room temperature. Do not take this medicine if you are allergic to sorafenib.  

Alternate Brands

Side effects  soranib

This medicine may cause some major and minor side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment.  

Common side effects 

  • Fatigue  

  • Weight loss 

  • Abdominal pain  

  • Vomiting  

  • Fever  

  • Bloating  

  • Blurred vision  

  • Nausea  

  • Bleeding gums  

  • Headache  

  • Difficulty in breathing  

  • Diarrhea  

  • Hand-foot skin reaction  

  • Rash  

  • Pounding in the ears  

  • Irregular heartbeat  

  • Constipation  

  • Seizures  

  • Sore throat  

  • Indigestion  

  • Pale skin  

  • Coughing up blood  

  • Dizziness  

  • Difficulty in swallowing  

  • High blood pressure  

  • Dehydration  

  • Anemia  

  • Weakness  

  • Chest pain 

  • Lightheadedness  

  • Nosebleeds  

  • Heartburn  

  • Trouble in sleeping  

  • Change of taste  

  • Blurred vision  

  • Swelling in your face  

  • Unusual bleeding  

Note- immediately contact your doctor if any side effect occurs 

Dosage  of Soranib

Take this medicine as prescribed by your doctor. Do not crush or break the tablet. Take this medicine on an empty stomach one hour before or two hours after the meals.  

Missed dose  

  •  It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately.  

Overdose  

  • In case of an overdose, the doctor will provide emergency medical treatment.  

Warnings  of soranib

Before starting treatment with the Soranib tablet, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.  

  •  Contraception  

  • Use effective methods of contraception to prevent pregnancy while taking this medicine.  

  • Children and adolescents  

  • This medicine is not advisable for use in children and adolescents.  

Warnings for female  

Pregnancy 

  • Do not use Soranib tablets if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.  

Breastfeeding 

  • This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication. 

Precautions of soranib

  • This medicine can reduce the number of white blood cells in the body.  

  • Soranib tablets may increase the risk of bleeding.  

  • Regular monitoring of blood pressure is required during the treatment with this medicine.  

  • The use of this drug may cause dizziness  

  • This medicine should be used with caution in patients with low blood glucose levels.  

  • Consult a doctor if you are suffering from heart disease. 

  • Hand-foot skin reaction generally appears in the first six weeks of treatment.   

Cautions of soranib

  • Do not crush, chew, or break the tablet.   

  • Do not drive or operate heavy machinery.  

  • Not safe for pregnant women.  

  • Do not breastfeed while receiving this medication.  

Q1. What is Soranib (sorafenib)?  

Ans. Soranib tablets are used to treat certain types of cancer (liver, kidney, and thyroid cancer). This medicine helps to prevent the multiplication of cancer cells.   

Q2. How does Soranib (Sorafenib) work?  

Ans. Soranib tablets are anti-cancer medications. It works by blocking the action of a protein that signals the cancer cells to multiply. This helps in slowing down the growth of cancer cells. 

Q3. What are the side effects?  

Ans. Some common side effects are:- nausea, fever, abdominal pain, irregular heartbeat, seizures, diarrhea, bleeding, fatigue, indigestion, etc.  

Q4. In what strength is it available?  

Ans. It is available in the strength of 200mg.  

Q5. What happens if I miss a dose?  

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q6. What should I avoid while receiving this medicine?  

Ans.  Follow your doctor’s instructions about any restrictions on food and other activities. 

Q7. What are self-care tips?  

Ans. Keep yourself hydrated and maintain good nutrition.  

Q8. Can I consume alcohol while taking this medicine?  

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol.  

Q9. Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended for pregnant women. 

Q10. Can I drive after taking this medicine?  

Ans.  This medicine may affect your vision. Do not drive if any symptoms occur.  

Q11. How to take this medicine?  

Ans. Take this medicine as prescribed by your doctor. Do not chew or crush the tablet.  

Q12. Can I take this medicine during breastfeeding?  

Ans. This medicine is not recommended in breastfeeding unless it is necessary. 

Q13. Does this medicine affect liver function?  

Ans. Please contact your doctor before consuming this drug. 

Q14. What are the storage conditions?  

Ans. Store this medicine at room temperature.  

Interactions of soranib

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.  

Medicine interaction  

  • Amiodarone 

  • Clozapine  

  • Moxifloxacin  

  • Bepridil  

  • Gatifloxacin  

  • Lomitapide  

  • Ziprasidone  

Disease interaction  

  • This medication should be used with caution in patients with a history of interstitial pneumonitis.  

Alcohol interaction  

  • Interaction with alcohol is unknown. Please contact your doctor before consuming alcohol.  

Contraindications of soranib

  • This medicine is not recommended in patients known to be hypersensitive. 

  • Soranib medicine is not recommended for use in patients with a known allergy to sorafenib.  

  • This medicine is not recommended for use with carboplatin in patients with squamous cell lung cancer.  

Above Content has been reviewed by Professionals