SOVIHEP-V

Side effects of Sovihep-V

This medicine may cause some mild or severe side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment. 

Common side effects  

• Headache  

• Diarrhea  

• Nausea  

• Tiredness  

• Difficulty in breathing  

• Cough  

• Loss of appetite  

• Muscle pain  

• Rash  

• Back pain  

• Loss of strength  

• Irregular heartbeat  

• Chest pain  

• Dizziness  

• Unusual tiredness  

• Slow heart rate  

• Irritability  

• Fatigue  

• Anemia  

• Chills  

• Unusual weakness  

• Itching  

• Blurred vision  

• Cramps  

• Allergic reaction  

• Insomnia  

• Pale skin  

Note- immediate medical attention is required if any side effect occurs 

Dosage of Sovihep-V

Take this medicine as prescribed by your doctor. Do not skip or miss your dosing schedule. This medicine can be taken with or without food.  

Missed dose  

•  It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately.  

Overdose  

• In case of an overdose, the doctor will provide emergency medical treatment.  

Warnings of Sovihep-V

Before starting treatment with this medication, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.  

 Contraception  

• Use effective methods of contraception to prevent pregnancy while taking this medicine.  

Children and adolescents  

• This medicine is not advisable for use in children and adolescents. 

Warnings for female  

Pregnancy 

• Do not use this medicine if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.  

Breastfeeding 

• This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication. 

Precautions of Sovihep-V

• This medicine is not recommended in patients who have a history of Hepatitis B infection.  

• Regular monitoring of liver function and the amount of hepatitis C virus (HCV) in your body is required.  

• Close monitoring of kidney function is required.  

• Inform your doctor if you experience any side effects like nausea, fatigue, headache, anemia, and rashes.  

• Do not stop taking this medicine without your doctor’s advice. 

• Contact your doctor if you have complications in the liver other than HCV infection.  

Cautions of Sovihep-V

• Do not drive or operate heavy machinery.  

• Do not skip the regular dosing schedule. 

• Not safe for pregnant women.  

• Do not breastfeed while receiving this medication.  

• Do not crush or break the tablet. 

Q1.  What is Sovihep V (Sofosbuvir and Velpatasvir)?  

Ans. Sovihep V tablet is a combination of two antiviral medicines Sofosbuvir and Velpatasvir. It works by removing the virus from the blood over a period of time.  

Q2. How does this medication work? 

Ans. It works by blocking different steps in the reproduction of viruses. 

Q3. What are the side effects?  

Ans. Some common side effects are:- nausea, fatigue, headache, anemia, rashes, muscle pain, insomnia, dizziness, blurred vision, etc.  

Q4. How to take this medicine?  

Ans. Take this medicine as prescribed by your doctor. Do not crush or break the tablet.  

Q5. What happens if I miss a dose?  

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q6. In what strength is it available?  

Ans. It is available in the strength of 100mg/400mg (Sofosbuvir 400mg + Velpatasvir 100mg) 

Q7. What should I avoid while receiving this medicine? 

Ans. Follow your doctor’s instructions about any restrictions on food and other activities.  

Q8. Can I consume alcohol while taking this medicine?  

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q9. Can I take this medicine during breastfeeding?  

Ans. This medicine is not recommended in breastfeeding unless it is necessary. 

Q10. Can I drive after taking this medicine?  

Ans. This medicine may affect your vision. Do not drive if any symptoms occur.  

Q11. Does this medicine affect liver function?  

Ans. Please contact your doctor before consuming this drug. 

Q12. What are the storage conditions?  

Ans.  Store this medicine at room temperature. Keep it away from heat and light.  

Q13.  Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended for pregnant women. 

Q14. Does this medicine affect kidney function?  

Ans. Please contact your doctor before consuming this drug. 

Interactions of Sovihep-V

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.  

Medicine interactions  

• Carbamazepine  

• Fosphenytoin  

• Dexamethasone  

• Lorlatinib  

• Rifampicin  

• St. john’s wort  

Disease interactions  

• Immunosuppression  

• Renal impairment  

• Hepatic impairment  

Alcohol interaction 

• Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.  

Contraindications 

• Do not take this medicine if you are allergic to Sofosbuvir and Velpatasvir.  

• This medicine is not recommended in patients known to be hypersensitive. 

Reference

• Dolutegravir: Drug information and uses available at: https://medlineplus.gov/druginfo/meds/a616034.html, https://www.mayoclinic.org/drugs-supplements/sofosbuvir-and-velpatasvir-oral-route/proper-use/drg-20312336?p=1, and https://www.drugs.com/sofosbuvir-and-velpatasvir.html.

Dolutegravir: Mechanism, Side Effects, and dosages available at: https://medlineplus.gov/druginfo/meds/a616034.html, https://www.webmd.com/drugs/2/drug-172067/sofosbuvir-velpatasvir-oral/details, and https://my.clevelandclinic.org/health/drugs/20582-sofosbuvir-velpatasvir-oral-tablets.