Stivarga 40mg Tablet

1. Elliott, W. T., & Chan, J. (2013). Pharmacology Update: Regorafenib Tablets (Stivarga®). Internal Medicine Alert, 35(7).
2. Li, Y., Qi, L., Yang, C., Zhao, N., & Wang, X. (2025). A randomized, open-label, two-period crossover study to evaluate the bioequivalence and food effect between two formulations of regorafenib in healthy adult participants. Frontiers in Pharmacology, 16, 1511558.
3. Dave, N., & Oncology, P. T. Positive Quality Intervention: Regorafenib (Stivarga®) in Metastatic Colorectal Cancer.
4. Zhang, Q., Wang, Z., Wu, J., Zhou, Z., Zhou, R., & Hu, W. (2021). Bioequivalence and pharmacokinetic evaluation of two oral formulations of regorafenib: an open-label, randomised, single-dose, two-period, two-way crossover clinical trial in healthy Chinese volunteers under fasting and fed conditions. Drug Design, Development and Therapy, 3277-3288.
5. Müller, M., Wiedey, R., Hoheisel, W., Serno, P., & Breitkreutz, J. (2021). Impact of co-administered stabilizers on the biopharmaceutical performance of regorafenib amorphous solid dispersions. European Journal of Pharmaceutics and Biopharmaceutics, 169, 189-199.

Side effects are unwanted symptoms that can occur from any medical treatment. Like other medications, the Stivarga 40mg Tablet can also have adverse effects on the body, most of which resolve without the need for medical attention.
Some common side effects include:
Vomiting
Infection
Weakness
Nausea
Anxiety
Weight loss
Swelling
Sore throat
Loss of appetite
Dizziness
Headache
Anemia
High blood pressure
Low blood platelets
Diarrhea
Blurred vision
Inform your doctor immediately if you experience any persistent or unusual side effect.

The dosage and duration of treatment with Stivarga 40mg Tablet determined by the doctor as per patient's health condition and other medical factors. This tablet should be taken on fixed time everyday after light or low-fat meal. Swallow the tablets whole with water and don't chew, crush or break it. Do not change or stop the dose without informing your doctor.

It is advisable not to miss a dose of Regorafenib medicine. If you miss a scheduled dose of this medicine, contact your doctor immediately.  ​

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