Stivarga 40mg Tablet

Stivarga 40mg Tablet

Prescription requiredRx Required

Salt Composition: Regorafenib

Expiry Date: 01/2028

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28 tablet

About The Product

Colorectal and Liver cancer

Stivarga 40mg Tablet is an anticancer medicine. This medication is used in the treatment of various types of cancer, including colorectal cancer, gastrointestinal stromal tumors (GIST), and liver cancer (hepatocellular carcinoma). It contains Regorafenib as its active ingredient, which works by blocking the growth of cancer cells and cutting off the blood supply that tumors need to grow.

Reference

1. Elliott, W.

T., & Chan, J. (2013).

Pharmacology Update: Regorafenib Tablets (Stivarga®). Internal Medicine Alert, 35(7).

2. Li, Y., Qi, L., Yang, C., Zhao, N., & Wang, X.

(2025). A randomized, open-label, two-period crossover study to evaluate the bioequivalence and food effect between two formulations of regorafenib in healthy adult participants.

Frontiers in Pharmacology, 16, 1511558. 3.

Dave, N., & Oncology, P. T.

Positive Quality Intervention: Regorafenib (Stivarga®) in Metastatic Colorectal Cancer. 4.

Zhang, Q., Wang, Z., Wu, J., Zhou, Z., Zhou, R., & Hu, W. (2021).

Bioequivalence and pharmacokinetic evaluation of two oral formulations of regorafenib: an open-label, randomised, single-dose, two-period, two-way crossover clinical trial in healthy Chinese volunteers under fasting and fed conditions. Drug Design, Development and Therapy, 3277-3288.

5. Müller, M., Wiedey, R., Hoheisel, W., Serno, P., & Breitkreutz, J.

(2021). Impact of co-administered stabilizers on the biopharmaceutical performance of regorafenib amorphous solid dispersions.

European Journal of Pharmaceutics and Biopharmaceutics, 169, 189-199.

Side Effects

  • Side effects are unwanted symptoms that can occur from any medical treatment.
  • Like other medications, the Stivarga 40mg Tablet can also have adverse effects on the body, most of which resolve without the need for medical attention.
  • Some common side effects include: Vomiting Infection Weakness Nausea Anxiety Weight loss Swelling Sore throat Loss of appetite Dizziness Headache Anemia High blood pressure Low blood platelets Diarrhea Blurred vision Inform your doctor immediately if you experience any persistent or unusual side effect.

How To Use

  • The dosage and duration of treatment with Stivarga 40mg Tablet determined by the doctor as per patient's health condition and other medical factors.
  • This tablet should be taken on fixed time everyday after light or low-fat meal.
  • Swallow the tablets whole with water and don't chew, crush or break it.
  • Do not change or stop the dose without informing your doctor.

Safety Advice

Alcohol

Avoid the consumption of alcohol while taking Stivarga 40mg Tablet as alcohol can reduce the effectiveness of the medicine and worsen the symptoms

Pregnancy

Do not take Stivarga 40mg Tablet without consulting the doctor in case of pregnancy, as it is an unsafe medicine during this period.

Breast Feeding

Stivarga 40mg Tabletis unsafe to use during breastfeeding as it may cause toxicity to the baby.

Driving

Stivarga 40mg Tablet may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.

Kidney

Stivarga 40mg Tablet is safe for use in kidney disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet.

Liver

Consumption of Stivarga 40mg Tablet should be avoided without informing the doctor if you have any liver-related issues.

Missed Doses

  • It is advisable not to miss a dose of Regorafenib medicine .
  • If you miss a scheduled dose of this medicine, contact your doctor immediately. ​

FAQs

Regorafenib tablets are used in the treatment of colorectal cancer, gastrointestinal stromal tumors (GIST), and liver cancer (hepatocellular carcinoma).


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