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30 Tablet
Tenofovir Disoproxil Lamivudine and Efavirenz Tablets
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Overview
Trioday Tablet is an antiretroviral medication combination. It is prescribed to treat infections caused by the human immunodeficiency virus (HIV). To manage or treat AIDS (acquired immunodeficiency syndrome), it improves the immune system to fight against HIV. Trioday Tablet prolongs a person's life by preventing the spread of HIV within the body and lowering the chance of developing HIV-related illnesses. The way this medication functions is by stopping the infection from growing. The active ingredients in Trioday tablets are efavirenz, lamivudine, and tenofovir disoproxil fumarate. Efavirenz belongs to the class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs), which includes antiretroviral drugs. The antiretroviral or antiviral drug lamivudine with tenofovir disoproxil fumarate is a member of the class of drugs known as nucleotide reverse transcriptase inhibitors (NRTI).
Treatment of HIV infections
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trioday are:
Elevated levels of serum amylase
Blood in urine
Increased transaminase levels in the blood
Cough
Headache
Nausea
Insomnia (difficulty in sleeping)
Weakness
Depression Diarrhea
Rash
Body Pain
Fever
Decreased white blood cell count (neutrophils)
Peripheral neuropathy (tingling and numbness of the feet and hands)
Pneumonia
Increased triglyceride level in the blood
Anxiety
Vomiting
Indigestion
As directed by your physician, take this medication for the prescribed amount of time. Eat it all at once. Avoid chewing, crushing, or breaking it. The Trioday Tablet should be taken without food. Trioday Tablets should be taken as directed by your physician or on an empty stomach. For optimal safety, take this medication exactly as prescribed by your doctor. Take the entire Trioday Tablet with a glass of water.
The active ingredients in Trioday tablets are efavirenz, lamivudine, and tenofovir disoproxil fumarate. Efavirenz belongs to the class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs), which includes antiretroviral drugs. The antiretroviral or antiviral drug lamivudine with tenofovir disoproxil fumarate is a member of the class of drugs known as nucleotide reverse transcriptase inhibitors (NRTI). They function by stopping the HIV from growing, which lowers the infection's level in your body. Also, they raise the number of CD4 cells in your blood, which are white blood cells that fight infection. By inhibiting the reverse transcriptase enzyme, which is required for viral replication, nucleoside reverse transcriptase inhibitors (NRTIs), such as lamivudine and tenofovir disoproxil fumarate, prevent HIV from proliferating. Efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI), further reduces HIV replication by binding directly to the reverse transcriptase enzyme and altering its structure to prevent it from working. Together, these drugs reduce the viral load and stop HIV infection from spreading.
Alcohol
consult your doctor
The interaction of alcohol with the Trioday tablet is not known. It is advisable not to consume alcohol while taking this injection. It is advised to consult your doctor for further information.
Pregnancy
consult your doctor
Trioday Tablet provides a clear risk to the developing baby, making it unsuitable to use while pregnant. In certain life-threatening circumstances, however, if the advantages are greater than the possible risks, the doctor might sometimes recommend it. Please speak with your physician.
Breast Feeding
consult your doctor
Trioday tablet is probably not safe if you're breastfeeding. Kindly consult your doctor.
Driving
unsafe
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking the Trioday tablet.
Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking the Trioday tablet.
Liver
safe if prescribed
Inform your doctor before starting Trioday tablet if you have liver disease to avoid any serious side effects.
It is advised to use effective birth control methods to avoid pregnancy. Some drugs can cause birth defects, miscarriage, or death to an unborn baby if the mother or father is using this medicine. Moreover, this medicine may pass to the unborn baby.
Consult your doctor if you observe symptoms such as abdominal pain, loss of appetite, dark urine, or yellowing of the eyes or skin. These symptoms indicate the presence of Jaundice in the body.
It is advised to tell your doctor about all medicines (multivitamins, herbal supplements) you're taking currently before starting your course with Trioday medicine. There are chances that many drugs can interact, and some drugs should not be used together.
Inform your healthcare expert in case of a history of severe blood infection, active tuberculosis, liver problems, or any serious health disorder.
Birth control is mandatory in order to avoid transmission of HIV infection to your partner and to avoid an unwanted pregnancy.
No, this medicine is not a permanent cure for HIV. It is an antiretroviral medication that helps to inhibit the multiplication process of the virus and slows down the growth of the disease. It is given as a combination therapy to manage the HIV infection lifetime.
Yes, the Trioday Tablet is an antiretroviral drug belonging to the drug class of nucleoside reverse transcriptase inhibitors (NRTIs).
Common side effects of taking this medicine are diarrhea, headache, fatigue, dizziness, difficulty breathing, Diarrhea, Vomiting, Nausea, Weight gain, and Headache.
Taking this medicine may lead to the development of a skin rash. This rash may become severe or life-threatening in extreme cases. Consult your doctor whenever you notice any skin rashes.
Arribas, J. R., et al. (2008). Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: 96-week analysis. Journal of Acquired Immune Deficiency Syndromes, 47(1), 74–78.
Cassetti, I., et al. (2006). The safety and efficacy of tenofovir DF (TDF) + lamivudine (3TC) + efavirenz (EFV) through 5 years in antiretroviral-naïve patients. 8th International Congress on Drug Therapy in HIV Infection, Glasgow, UK.
DeJesus, E., et al. (2009). Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral naïve patients: 96-week analysis. Journal of Acquired Immune Deficiency Syndromes, 47(1), 74–78.
Efficacy and Safety of Tenofovir and Lamivudine in Combination with Efavirenz in Patients Co-infected with Human Immunodeficiency Virus and Hepatitis B Virus in China, (n.d.). PubMed. Retrieved from the PubMed database.
Gallant, J., et al. (2005). Tenofovir DF (TDF) in combination with lamivudine (3TC) and efavirenz (EFV) in antiretroviral naive HIV infected patients: a 4-year follow-up.
Pujari, S., Dravid, A., Gupte, N., Joshi, K., & Bele, V. (2008). Effectiveness and safety of a generic fixed-dose combination of tenofovir/emtricitabine/efavirenz in HIV 1 infected patients in Western India. Medscape Journal of Medicine, 10(8), 196.
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Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.