VELPANAT

Mfd. by :- Natco Pharma Ltd (Fulfilled By : Magicine Pharma)

velpanat

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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PACKAGE

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Medicine details

Brand name - Velpanat
Generic name - Sofosbuvir/Velpatasvir
Manufacturer - Natco Pharma Ltd
Salt composition - Sofosbuvir and Velpatasvir
Storage - Store at room temperature (10-30°C)
Dosage form - Oral (tablet)
Strength - 400mg + 100mg
Packaging - Bottle of 28 tablets
Gender - Unisex
Active ingredient - Sofosbuvir/Velpatasvir
Prescription required - Yes
Indication - Used in the treatment of chronic hepatitis C virus (HCV) infection

Description

Velpanat is a combination of two antivirals. It is used in the treatment of chronic hepatitis C virus infection. This combination of Sofosbuvir and Velpatasvir is known to be the first once-daily single-tablet treatment with pangenotypic activity. Velpanat (Sofosbuvir/Velpatasvir) works to fight against the virus in order to resolve the infection. Velpanat should be taken in prescribed dose and duration. No alterations or manipulations should be done, unless your healthcare provider tells you.

Pharmacodynamics

Velpanat is a combination of velpatasvir & sofosbuvir. Sofosbuvir is a nucleotide analog NS5B polymerase inhibitor and Velpatasvir is an NS5A replication complex inhibitor. Sofosbuvir is used in the treatment of genotype 1, 2, 3 and 4 HCV infection with different medicines, wherein duration depends on the HCV genotype. Velpatasvir is a novel NS5A inhibitor. It has potent in vitro anti-HCV activity across all genotypes at the picomolar level. The effect of Sofosbuvir (Velpanat) 400 mg (recommended dosage) and 1200 mg (three times the recommended dosage) on QTc interval was calculated in an active-controlled (moxifloxacin 400 mg) thorough QT trial. Sofosbuvir (Velpanat) does not prolong QTc to any clinically relevant extent, at a dose (three times the recommended dose). The effect of Velpatasvir (Velpanat) 500 mg (five times the recommended dosage) was calculated in an active-controlled (moxifloxacin 400 mg) thorough QT trial. Velpatasvir (Velpanat) does not prolong QTc interval to any clinically relevant extent, at a dose five times the recommended dose.

Ingredients

The active ingredient of Velpanat is Sofosbuvir/Velpatasvir.

Usage of medicine

Velpanat (Sofosbuvir/Velpatasvir) is used in the treatment of chronic hepatitis C virus (HCV) infection. Hepatitis C is an infection in the liver, which is caused by Hepatitis C Virus. Velpanat (Sofosbuvir/Velpatasvir) helps to control this infection.

Alternate brands

  • Velpaclear Tablet

  • Sofocure-v Tablet

  • Sovihep V Tablet

  • Velasof Tablet

  • Resof total tablet

Side-effects

Common side-effects

  • Tiredness

  • Cough

  • Lower back pain

  • Skin rash

  • Headache 

  • Nausea

  • Diarrhea 

  • Muscle pain

  • Cramps 

  • Loss of appetite

Serious side-effects

  • Anemia

  • Insomnia

  • Blurred vision

Dosage

Take this medicine exactly as your healthcare provider tells you. Do not crush, chew or break the tablet. Swallow as a whole.

Missed dose

Please consult your healthcare provider in case you miss a dose. Do not double the dose in order to cover up, unless your doctor tells you.

Overdose

Seek emergency medical support.

 

Warning and precautions

  • Velpanat should be used with caution in patients with severe kidney disease.

  • Do not stop taking this medicine unless your healthcare provider tells you.

  • It is not yet known whether it is safe to consume alcohol with this medicine or not. Please consult your healthcare provider.

  • After taking this medicine, you may feel dizzy. If you experience such side effects, avoid driving and operating heavy machines.

  • Velpanat medicine is safe (only if prescribed) during breastfeeding. Make sure to tell your healthcare provider regarding all the side effects or changes you experience.

FAQs

Q1- What is Velpanat (Sofosbuvir/Velpatasvir)?

A- Velpanat (Sofosbuvir/Velpatasvir) is used in the treatment of chronic hepatitis C virus (HCV) infection.

Q2- How should I take Velpanat?

A- Take this medicine exactly as your healthcare provider tells you. Do not chew, crush or break it.

Q3- What are the possible side effects of Velpanat?

A- There can be side effects such as fever, dizziness, cough, diarrhea, nausea, insomnia and anemia. Please contact your healthcare provider if you experience these or any other side effects.

Q4- In what strength is Velpanat available?

A- It is available in the strength of 400mg + 90mg.

Q5- What should be done if I miss a dose?

A- Please consult your healthcare provider if you miss a dose. Do not adjust the dose as per your wish.

Q6- What should I avoid while consuming this medicine?

A- Avoid food items that can stress your liver such as fatty or sugary foods.

Q7- What are self care tips?

A- Drink plenty of water.

Q8- Can I take this medicine during pregnancy?

A- Please consult your healthcare provider before taking this medicine during pregnancy.

Q9- Can I drive after taking this medicine?

A- Do not drive and operate heavy machines if you feel dizzy or unwell after taking Velpanat.

Q10- What are the storage conditions?

A- Store at room temperature (10-30°C). Keep away from direct light, heat and moisture.

 

Above Content has been reviewed by Professionals