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VENCLYXTO

Mfd. by :- Abbvie (Fulfilled By : Magicine Pharma)

Venclyxto

SAFE AND SECURE


Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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DESCRIPTION

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PACKAGE

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Brand Name - Venclyxto

Generic Name - Venetoclax

Manufacturer - Abbvie 

Dosage Form - Tablets

Strength - 100mg 

Indication - Blood Cancer

Storage - Store at room temperature. 

Venclyxto is an anti-cancer medicine available by prescription. It is used in the treatment of certain types of blood cancers. This drug is prescribed to treat mainly small lymphocytic lymphoma, chronic lymphocytic leukemia, and acute myeloid leukemia. It is available in the strength of 100mg as tablets for oral use. Venclyxto contains Venetoclax that belongs to the class of B-cell lymphoma-2 (BCL-2) inhibitors. It is a kind of targeted therapy medicine.

Pharmacodynamics

Venetoclax promotes rapid and extensive apoptosis of CLL cells, which can happen in 24 hours and result in tumor lysis syndrome. Patients with relapsed CLL (chronic lymphocytic leukemia) or SLL (small lymphocytic leukemia), even those with poor prognostic features, responded well to venetoclax, a drug that selectively targets BCL2. This medication is not expected to influence the cardiac QT interval.

Interactions 

Venclyxto (Venetoclax) is a specialty medicine that can interact with a number of other drugs and diseases. Consult your doctor.

Medicine Interactions 

  • Baricitinib 
  • Cabozantinib
  • Fexinidazole 
  • Vandetanib

Disease Interactions

  • Hepatic impairment
  • TLS/renal
  • Vaccination 
  • Neutropenia

Alcohol Interactions

No interactions between Venclyxto (Venetoclax) tablets and alcohol are known. However, it is better to avoid drinking alcohol during this therapy. 

Contraindications 

Venclyxto (Venetoclax) tablets are not indicated for use in the following cases.

  • Neutropenia
  • Breastfeeding 
  • Anemia
  • Renal impairment
  • Hepatic disease
  • Thrombocytopenia

Alternate Brands 

The following are alternate brands for Venclyxto (Venetoclax) tablets.

  • Venclexta
  • Venex
  • Lucivenet
  • Ventoxen 

The common side effects of Venclyxto (Venetoclax) tablets are listed below. Ask your doctor about the ways to manage them at home.

  • Chills
  • Sore throat
  • Vomiting
  • Lower back pain
  • Fever
  • Headache
  • Nosebleeds 
  • Sneezing 
  • Cloudy urine
  • Rapid weight gain
  • Pain while urinating
  • Difficulty in breathing
  • Increased menstrual flow
  • Blood in urine
  • Frequent urination
  • Confusion
  • Seizures 
  • Loss of appetite
  • Nausea
  • Pale skin

Consult your doctor if you experience side effects for a long time.

 

Venclyxto (Venetoclax) tablets must be taken orally with water as per the prescription. Swallow the tablets. Don’t crush or chew them. 

Missed dose 

If you miss a dose of Venclyxto (Venetoclax) tablets, consult your doctor. Know the ways of coping with the skipped dose. Don’t take doubled strength the next time.

Overdose

If you overdose on Venclyxto (Venetoclax) tablets, seek immediate medical attention. You may require hospitalization in case of severe events.

 

Before starting Venclyxto (Venetoclax) therapy, make sure to consult your doctor and tell your:

  • Medical history
  • Medicines you already consume
  • Any known allergies

Contraception 

Use effective contraception and other safe sex practices during Venclyxto (Venetoclax) therapy to avoid pregnancy.

Driving 

Driving after the administration of Venclyxto (Venetoclax) tablets may not be safe. This is because the drug may cause dizziness and loss of concentration.

Warnings for Females

Pregnancy

Do not administer Venclyxto (Venetoclax) during pregnancy without knowing its potential risks and benefits from your doctor. It may cause severe harm.

Breastfeeding

Do not administer Venclyxto (Venetoclax) during breastfeeding without knowing its potential risks and benefits from your doctor. This drug may be excreted in mother’s milk.

Cautions

  • Don’t crush or chew Venclyxto (Venetoclax) tablets. 
  • Patients with severe neutropenia may require regular monitoring during Venclyxto (Venetoclax) therapy.
  • The use of Venclyxto (Venetoclax) tablets in liver patients must be done with caution to avoid adverse events

Q1. What is Venclyxto (Venetoclax)?

A- Venclyxto (Venetoclax) is used in the treatment of small lymphocytic lymphoma, chronic lymphocytic leukemia, and acute myeloid leukemia.

 

Q2- What are the side effects of Venclyxto (Venetoclax)? 

A- The side effects of Venclyxto (Venetoclax) include chills, sore throat, lower back pain, sneezing, cloudy urine, pale skin, difficulty in breathing, and loss of appetite.

 

Q3- How to take Venclyxto (Venetoclax)?

A- Venclyxto (Venetoclax) tablets must be taken orally with water as per the prescription. Swallow the tablets.

 

Q4- What is the strength of Venclyxto (Venetoclax)?

A- Venclyxto (Venetoclax) tablets have a strength of 100mg. 

 

Q5- How to store Venclyxto (Venetoclax)?

A- Store Venclyxto (Venetoclax) tablets at room temperature.

 

Q6- Can you take Venclyxto (Venetoclax) during pregnancy?

A- Do not administer Venclyxto (Venetoclax) during pregnancy without knowing its potential risks and benefits from your doctor. It may cause severe harm.

 

Q7- Can you take Venclyxto (Venetoclax) during breastfeeding?

A- Do not administer Venclyxto (Venetoclax) during breastfeeding without knowing its potential risks and benefits from your doctor. This drug may be excreted in mother’s milk.

 

Q8- Can you drive after taking Venclyxto (Venetoclax)?

A- Driving after the administration of Venclyxto (Venetoclax) tablets may not be safe. This is because the drug may cause dizziness and loss of concentration.

 

Q9- Can you drink alcohol during Venclyxto (Venetoclax) therapy?

A- No interactions between Venclyxto (Venetoclax) tablets and alcohol are known. However, it is better to avoid drinking alcohol during this therapy.

 

Q10- Can liver disease patients take Venclyxto (Venetoclax)?

A- The use of Venclyxto (Venetoclax) tablets in liver patients must be done with caution to avoid adverse events.

 

Above Content has been reviewed by Professionals