Versavo 400mg Injection
Prescription Required
Marketed By
dr.reddy
Pack of
1 Injection
Salt Composition
Bevacizumab
Storage
Keep in cold place
₹12010₹55005
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Inclusive of all taxes
1
Versavo 400mg Injection
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Overview
Versavo 400mg Injection belongs to the category of anticancer medicines. This medication is used to treat various types of cancer, such as colon and rectum cancer, kidney cancer, non-small cell lung cancer, brain tumors, cervical and ovarian cancer. The growth of cancer cells is uncontrollable and abnormal in the human body. It is difficult to diagnose cancer in the early stages. When diagnosed in advanced stages, only the symptoms of the disease can be reduced. Versavo Injection is typically administered in combination with another anticancer medication as part of a treatment regimen to enhance the treatment's efficacy. Versavo 400mg solution is an effective medicine, which is given in the vein through a small needle or through a port (placed under your skin).
Indication
Rectal Cancer, Colorectal Cancer, Chemotherapy, Brain tumor
Uses
Cancer of the colon and rectum
Ovarian cancer
Cervical cancer
Kidney cancer
Brain tumor
Non-small cell lung cancer
Side Effects
The human body reacts differently to Versavo 400mg injection. Response or undesired symptoms vary from individual to individual. Usually, they disappear with time as the body adjusts to the medicine; these side effects don't need special medical attention. Whereas if the symptoms don't disappear with time or you have severe side effects, then consult your doctor immediately. Some of the common side effects of Versavo Injection are mentioned below:
Fever
Rashes
Headache
Dizziness
Sleepiness
Constipation
Blurred vision
High blood pressure
Indigestion & vomiting
Numbness or tingling
Weight loss or weight gain, swelling of hands and feet
Nausea and reduced appetite
Slow wound healing after surgery
Anxiety, depression, confusion, and mood swings. Serious side effects are:
Nerve damage
Low WBC count
Palpitations
Difficulty breathing
Sudden pain in the chest
Pain and swelling of the legs
Serious allergic reactions
Protein in urine
Severe infections, Gut perforation
Mouth sores, dryness
Shortness of breath
Nosebleeds and high risk of bleeding
Heart problems with an increase in heart rate
Blood clots in the arteries and blood vessels of the lungs
How To Use
Versavo 400mg Injection is a prescription-based anticancer drug. It is advised to take this injection after consulting your healthcare expert. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
How It Works
Versavo 400mg solution, an anti-angiogenic medication, works by blocking vascular endothelial growth factor (VEGF), which is a protein. It basically functions by cutting the oxygen supply and nutrients to cancerous cells by stopping the formation of blood vessels that supply them. It also reduces the size of the tumor by killing the cancer cells.
Safety Advice
Alcohol
consult your doctor
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Versavo 400mg Injection. Consult your doctor for further information.
Pregnancy
consult your doctor
Versavo 400mg Injection may be considered unsafe during pregnancy. Please consult your doctor in such a condition. According to some research data, taking Versavo 400mg injection during pregnancy has shown harmful effects on the developing baby.
Breast Feeding
consult your doctor
Versavo 400mg Injection is probably not safe if you're breastfeeding. Kindly consult your doctor before taking Versava 400mg medicine while breastfeeding, as there are chances that it may pass to the developing baby through the breast milk of the mother.
Driving
unsafe
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Versavo 400mg Injection.
Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking Versavo 400mg Injection. Patients with renal impairment must be careful while taking Versavo 400mg injection. They may require adjustment in the dose.
Liver
safe if prescribed
Inform your doctor before starting Versavo 400mg Injection if you have liver disease to avoid any serious side effects. Patients with hepatic impairment must be careful while taking Versavo 400mg injection. They may require adjustment in the dose.
Missed Doses
It is advised not to miss any scheduled dosage of Versavo 400mg Injection. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
Quick Tips
It is advised to use effective birth control methods and avoid pregnancy during the treatment with Versavo 400mg Injection.
A person should avoid smoking while undergoing treatment with Versavo 400mg Injection. Smoking may reduce the effectiveness of medicine.
Monitor your blood sugar & pressure, Kidney & Liver function (KFT & LFT), Heart function at proper intervals after taking Versavo.
Swelling of hands, lips, and weight gain are some of the side effects observed after taking this medicine. To reduce them, the doctor may suggest some medication.
Skin becomes extremely sensitive after taking Versavo 400mg Injection. It is advised to cover your skin exposed to direct sun rays and use high SPF sunscreen before going out.
FAQs
This medicine comes under the immunotherapy drugs. There is the possibility of using this drug alone as monotherapy or in combination with chemotherapy or immunotherapy medications to reduce the symptoms and increase the survival rate of the patient.
If you are planning for pregnancy, it is advisable to consult your doctor in such cases. Use effective birth control methods while undergoing treatment with this medicine.
There are chances that taking this medicine may increase the risk of bleeding complications and delayed wound healing. It is recommended to avoid planning for surgery during this time.
This injection is given intravenously through an infusion by an experienced nurse or doctor. The dosage of the drug is given considering the patient’s body weight, height, and age.
Taking Versavo 400mg infusion may cause anaemia as this medicine reduces the number of red blood cells. Its symptoms include a feeling of dizziness, lightheadedness, lack of energy, pale skin, etc.
No, taking Chemotherapy is a must, and it should not be skipped. Versavo 400mg infusion is given along with chemotherapy.
One should consult the doctor first before taking Versava 400mg infusion because this medicine may increase blood pressure and can increase the incidence of hypertension.
Chemotherapy targets and destroys the rapidly dividing cancer cells to stop their spread and growth. While Versavo 400mg infusion cuts off the blood supply that helps shrink the tumor and prevent it from growing further by inhibiting the formation of new blood vessels.
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Reference
1. Xiao X, Zhang G, Sun B, Wang C, Wang X, Kong F, Jia Y. (2022). Comparison of efficacy and safety of bevacizumab biosimilar and original bevacizumab in non-squamous non-small cell lung cancer: a systematic review and meta-analysis. Transl Cancer Res;11(6):1472-1482.
2. Xu X, Zhang S, Xu T, Zhan M, Chen C, Zhang C. (2022). Efficacy and Safety of Bevacizumab Biosimilars Compared With Reference Biologics in Advanced Non-small Cell Lung Cancer or Metastatic Colorectal Cancer Patients: A Network Meta-Analysis. Front Pharmacol.
3. Vaidyanathan A, Vana P, Joshi N, Sourav B, Bhargava P, John G, Ramaswamy A, Ostwal V.(2025). Real-World Evidence for Comparative Outcomes between Innovator and Biosimilar Bevacizumab in Advanced Colorectal Cancers. South Asian J Cancer 6;13(4):296-299.
4. Apsangikar, Prasad Dattatray; Chaudhry, Sunil Ramdev; Naik, Manoj Murlidhar; Deoghare, Shashank Babarao1; Joseph, Jamila1. (2024). Comparative pharmacokinetics, efficacy, and safety of bevacizumab biosimilar to reference bevacizumab in patients with metastatic colorectal cancer. Indian Journal of Cancer, 54(3) p. 535-538.
5. Zhao Z, Zhao L, Xia G, Lu J, Shen B, Zhou G, Wu F, Hu X, Feng J, Yu S. (2023). Efficacy and safety of bevacizumab biosimilar compared with reference bevacizumab in locally advanced and advanced non-small cell lung cancer patients: A retrospective study. Front Oncol.
6. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics (2023): GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 71(3):209–49.
7. Garcia J, Hurwitz HI, Sandler AB, Miles D, Coleman RL, Deurloo R, et al. (2025). Bevacizumab (Avastin(R) in cancer treatment: A review of 15 years of clinical experience and future outlook. Cancer Treat Rev, 86:102017.
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