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Exkivity (Mobocertinib 40 Mg Capsule)

4.8
Google Rating

Prescription Required

Marketed By

takeda

Pack of

120 capsule

Salt Composition

Mobocertinib 40 mg Capsule

Storage

Keep in cold place

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Exkivity (Mobocertinib 40 Mg Capsule)

Exkivity (Mobocertinib 40 Mg...

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Overview

Exkivity is a targeted anticancer medicine with active ingredient Mobocertinib which belongs to tyrosine kinase inhibitor (TKI) class of drugs. It is prescribed to treat advanced non-small cell lung cancer (NSCLC) in adults with specific EGFR gene mutation.

This medicine works by inhibiting the EGFR exon 20 insertion mutations to reduce the uncontrolled growth of cancer cells. It should be taken in dose and duration as advice by the doctor. Don't take more than the recommended dose.


Indication

Lung Cancer

Uses

Non-small cell lung cancer

Side Effects

Exkivity (Mobocertinib 40 Mg Capsule) may cause some side effects that vary from one patient to another. Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.

Common side effects include:

  • Diarrhea
  • Vomiting
  • Nausea
  • Decreased appetite
  • Rash
  • Dry skin
  • Skin infection around nails
  • Tiredness
  • Mouth sores
  • Muscle or joint pain

Contact your healthcare provider if you face any unusual or persistent side effects.

How To Use

  • The dosage and treatment duration of the Exkivity are decided by the doctor according overall patient's health.
  • However the usual dose of this medicine is 160 mg orally once daily.
  • This tablet should be taken with or without food, but at the fix time every day to get effective results.
  • Don't miss a dose or overdose on the medicine.

How It Works

  • Exkivity is a targeted anticancer medicine with active ingredient Mobocertinib which belongs to tyrosine kinase inhibitor (TKI) class of drugs.
  • This medicine works by binding and inhibiting the Epidermal growth factor receptor (EGFR) exon 20 insertion mutations to reduce the uncontrolled growth of cancer cells.

Safety Advice

Alcohol

Avoid the consumption of alcohol while taking Exkivity, as alcohol can decrease the effectiveness of the medicine as well as worsen the symptoms.

Pregnancy

CONSULT YOUR DOCTOR

Do not take Exkivity (Mobocertinib) without consulting the doctor in case of pregnancy, as it can be unsafe to take it during this period.

Breast Feeding

CONSULT YOUR DOCTOR

Breastfeeding women should discuss the potential risks and benefits of the Exkivity (Mobocertinib) with their healthcare provider before starting treatment.

Driving

DANGER

Exkivity (Mobocertinib) may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving.

Kidney

PRECAUTION

Share your medical history with the doctor before starting the Exkivity (Mobocertinib). Do not take it without consulting a doctor if you have any kidney related issue.

Liver

PRECAUTION

Share your medical history with the doctor before starting the Exkivity (Mobocertinib). Do not take it without consulting a doctor if you have any liver related issue.

FAQs

What is the Exkivity (Mobocertinib) used for?

Exkivity is an anticancer tablet that is primarily used in the treatment of advanced non-small cell lung cancers.

How does Exkivity (Mobocertinib) work?

Exkivity (Mobocertinib) is an anticancer medicine that works by inhibiting the action of Epidermal growth factor receptor (EGFR) exon 20 insertion mutations to reduce the uncontrolled growth of cancer cells.

Is it safe to take Exkivity (Mobocertinib) in liver related condition?

No, don't take Exkivity (Mobocertinib) in case of liver related condition without consulting the doctor.

How long is the treatment with Exkivity (Mobocertinib)?

The doctor or the healthcare provider decides the course of treatment depending on the stage of the disease and the health of the patient.

Can I drive after taking Exkivity (Mobocertinib)?

It is advisable to avoid driving and operating heavy machinery as Exkivity may cause dizziness as one of the side effects.

References

  • Hanley, M. J., Camidge, D. R., Fram, R. J., & Gupta, N. (2024). Mobocertinib: Mechanism of action, clinical, and translational science. Clinical and Translational Science, 17(3), e13766.
  • Russell, M. C., Garelli, A. M., & Reeves, D. J. (2023). Targeting EGFR exon 20 insertion mutation in non–small cell lung cancer: amivantamab and mobocertinib. Annals of Pharmacotherapy, 57(2), 198-206.
  • Riely, G. J., Neal, J. W., Camidge, D. R., Spira, A. I., Piotrowska, Z., Costa, D. B., ... & Jänne, P. A. (2021). Activity and safety of mobocertinib (TAK-788) in previously treated non–small cell lung cancer with EGFR exon 20 insertion mutations from a phase I/II trial. Cancer discovery, 11(7), 1688-1699.
  • Yang, J. C. H., Zhou, C., Jänne, P. A., Ramalingam, S. S., Kim, T. M., Riely, G. J., ... & Nguyen, D. (2023). Characterization and management of adverse events observed with mobocertinib (TAK-788) treatment for EGFR exon 20 insertion–positive non–small cell lung cancer. Expert Review of Anticancer Therapy, 23(1), 95-106.
  • Gupta, N., Pierrillas, P. B., Hanley, M. J., Zhang, S., & Diderichsen, P. M. (2022). Population pharmacokinetics of mobocertinib in healthy volunteers and patients with non–small cell lung cancer. CPT: Pharmacometrics & Systems Pharmacology, 11(6), 731-744.
  • Duke, E. S., Stapleford, L., Drezner, N., Amatya, A. K., Mishra-Kalyani, P. S., Shen, Y. L., ... & Donoghue, M. (2023). FDA approval summary: Mobocertinib for metastatic non–small cell lung cancer with EGFR Exon 20 Insertion Mutations. Clinical Cancer Research, 29(3), 508-512.​

Ratings And Reviews

4.8
Google Rating

4.50/5

6 Ratings

5

50.00%

4

50.00%

3

0.00%

2

0.00%

1

0.00%

Tanvi Gupta

Happy with the product

Good quality product. Exkivity (Mobocertinib 40 Mg Capsule) has been working well for me. The delivery was on time and packaging was good. It's a reliable product and I'm happy with my purchase.

a year ago

Andrew Garcia

Worth every penny

Great product! Exkivity (Mobocertinib 40 Mg Capsule) has been working perfectly for me. The quality feels reliable and the value for money is excellent. Delivery was on time and packaging was good. Very satisfied with my purchase.

a year ago

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MARKETER DETAILS

takeda

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