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Bortecad 2.5mg Injection

Bortecad 2.5mg Injection

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Salt Composition: Bortezomib Injection IP

Expiry Date: 01/2028

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1 Injection

About The Product

​Multiple Myeloma, Mantle Cell Lymphoma​

Description

Bortecad 2.5mg Injection is a chemotherapy drug, specifically a proteasome inhibitor which is used in the treatment of multiple myeloma mantle cell lymphoma. It works by killing cancer cells by disrupting protein breakdown.

Medicine active ingredient is Bortezomib Injection IP. This medication should be administered under the supervision of an oncologist and the exact dosage and schedule is determined based on the patient's condition and response to the treatment.

Indication

Multiple myeloma, mantle cell lymphoma

Common Side Effects

  • Every medicine has several side effects, Bortecad 2.5mg Injection has also some side effects.
  • Some of them resolve on their own and some need proper medical attention.
  • Consult the doctor if the symptoms persist: ● High blood pressure ● Breathlessness ● Fungal infection ● Anemia ● Itching ● Pneumonia ● Dry skin ● Gastronintestinal bleeding ● Dehydration ● Motor neuropathy

Dosage And Administration

  • Bortecad 2.5mg Injection should be taken at once everyday to better efficacy.
  • You should take it exactly as the doctor recommends, do not skip or stop the medicine as this may reduce treatment effectiveness and allow cancer cells to grow.
  • Follow the oncologist instructions carefully regarding dosage, timings and treatment cycles.

Mechanism Of Action

Bortecad 2.5mg Injection is an anti-cancer medication.

Doctor use this as a first line therapy as it blocks the protein which is responsible in the growth of cancer cells and provides targeted action against malignant cells, helping to reduce tumor growth while minimizing damage to healthy cells.

Safety Advice

Alcohol
While taking Bortecad 2.5mg Injection, avoid using alcohol as it may interfere with the treatment and making it less effective in controlling the disease.
Driving
Bortecad 2.5mg Injection show side effects such as dizziness and sleepiness, doctors do not suggest driving at the time of treatment.
Pregnancy
Pregnant women avoid taking Bortecad 2.5mg Injection as it contains a potent anti-cancer agent that may harm the developing fetus.
Kidney
Patient with a kidney cancer avoid taking Bortecad 2.5mg Injection because this medication is specifically designed to treat certain cancers.
Liver
Bortecad 2.5mg Injection is not recommended to liver patients because impaired liver functions can affect how the medication is processed in the body.

Reference

• Duggett, N. A., & Flatters, S.

J. (2017).

Characterization of a rat model of bortezomib‐induced painful neuropathy. British journal of pharmacology, 174(24), 4812-4825. • Wang, W., Cho, H.

Y., Rosenstein-Sisson, R., Ramos, N. I.

M., Price, R., Hurth, K., ... & Chen, T. C.

(2017). Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model.

Journal of neurosurgery, 128(3), 695-700. • Bross, P. F., Kane, R., Farrell, A.

T., Abraham, S., Benson, K., Brower, M. E., ... & Pazdur, R.

(2004). Approval summary for bortezomib for injection in the treatment of multiple myeloma.

Clinical cancer research, 10(12), 3954-3964. • Zhu, Q., Lin, X., Liu, X., Hou, T., Zhang, M., Wang, N., ... & Xiao, W. (2018).

Dynamic changes of proteasome and protective effect of bortezomib, a proteasome inhibitor, in mice with acute pancreatitis. Biochemical and Biophysical Research Communications, 505(1), 126-133. • Li, C., Deng, T., Shang, Z., Wang, D., & Xiao, Y.

(2018). Blocking TRPA1 and TNF-α signal improves bortezomib-induced neuropathic pain.

Cellular Physiology and Biochemistry, 51(5), 2098-2110.

Certified Content

Written By
Venika Choudhary

Venika Choudhary

Medical Content Writer @ Magicine Pharma

Reviewed By
Dr. Aditya Sarin

Dr. Aditya Sarin

MBBS, MD - General Medicine, DrNB - Medical Oncology | 11 Years Experience

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