Marketed By
bdr pharma
Pack of
28 Tablets in Bottle
Salt Composition
Olaparib
Storage
keep in cold place
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Bdparp 100mg Tablet
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Overview
Bdparp 100mg tablet contains olaparib, which belongs to the antiviral drug category polyadenosine diphosphate-ribose polymerase (PARP). In cancer cells multiply in an uncontrolled manner. This tablet is used for treating prostate and pancreatic cancer; it can be given alone or in combination with other anticancer medications.
Indication
Ovarian Cancer, Breast Cancer
Uses
Audeh, M. W., Carmichael, J., Penson, R. T., Friedlander, M., Powell, B., Bell-McGuinn, K. M., & Tutt, A. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. The Lancet, 376(9737), 245-251.
Guo, X. X., Wu, H. L., Shi, H. Y., Su, L., & Zhang, X. (2024). The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials. Cancer Management and Research, 2553-2562.
Tutt, A., Robson, M., Garber, J. E., Domchek, S. M., Audeh, M. W., Weitzel, J. N. & Carmichael, J. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. The Lancet, 376(9737), 235-244.
van der Noll, R., Jager, A., Ang, J. E., Marchetti, S., Mergui-Roelvink, M. W., de Bono, J. S., & Schellens, J. H. (2020). Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2). Investigational New Drugs, 38(4), 1096-1107.
Yamamoto, N., Nokihara, H., Yamada, Y., Goto, Y., Tanioka, M., Shibata, T.,& Tamura, T. (2020). A Phase I, dose‐finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors. Cancer science, 103(3), 504-509.
Benefits
Audeh, M. W., Carmichael, J., Penson, R. T., Friedlander, M., Powell, B., Bell-McGuinn, K. M., & Tutt, A. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. The Lancet, 376(9737), 245-251.
Guo, X. X., Wu, H. L., Shi, H. Y., Su, L., & Zhang, X. (2024). The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials. Cancer Management and Research, 2553-2562.
Tutt, A., Robson, M., Garber, J. E., Domchek, S. M., Audeh, M. W., Weitzel, J. N. & Carmichael, J. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. The Lancet, 376(9737), 235-244.
van der Noll, R., Jager, A., Ang, J. E., Marchetti, S., Mergui-Roelvink, M. W., de Bono, J. S., & Schellens, J. H. (2020). Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2). Investigational New Drugs, 38(4), 1096-1107.
Yamamoto, N., Nokihara, H., Yamada, Y., Goto, Y., Tanioka, M., Shibata, T.,& Tamura, T. (2020). A Phase I, dose‐finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors. Cancer science, 103(3), 504-509.
Side Effects
Audeh, M. W., Carmichael, J., Penson, R. T., Friedlander, M., Powell, B., Bell-McGuinn, K. M., & Tutt, A. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. The Lancet, 376(9737), 245-251.
Guo, X. X., Wu, H. L., Shi, H. Y., Su, L., & Zhang, X. (2024). The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials. Cancer Management and Research, 2553-2562.
Tutt, A., Robson, M., Garber, J. E., Domchek, S. M., Audeh, M. W., Weitzel, J. N. & Carmichael, J. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. The Lancet, 376(9737), 235-244.
van der Noll, R., Jager, A., Ang, J. E., Marchetti, S., Mergui-Roelvink, M. W., de Bono, J. S., & Schellens, J. H. (2020). Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2). Investigational New Drugs, 38(4), 1096-1107.
Yamamoto, N., Nokihara, H., Yamada, Y., Goto, Y., Tanioka, M., Shibata, T.,& Tamura, T. (2020). A Phase I, dose‐finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors. Cancer science, 103(3), 504-509.
How To Use
Audeh, M. W., Carmichael, J., Penson, R. T., Friedlander, M., Powell, B., Bell-McGuinn, K. M., & Tutt, A. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. The Lancet, 376(9737), 245-251.
Guo, X. X., Wu, H. L., Shi, H. Y., Su, L., & Zhang, X. (2024). The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials. Cancer Management and Research, 2553-2562.
Tutt, A., Robson, M., Garber, J. E., Domchek, S. M., Audeh, M. W., Weitzel, J. N. & Carmichael, J. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. The Lancet, 376(9737), 235-244.
van der Noll, R., Jager, A., Ang, J. E., Marchetti, S., Mergui-Roelvink, M. W., de Bono, J. S., & Schellens, J. H. (2020). Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2). Investigational New Drugs, 38(4), 1096-1107.
Yamamoto, N., Nokihara, H., Yamada, Y., Goto, Y., Tanioka, M., Shibata, T.,& Tamura, T. (2020). A Phase I, dose‐finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors. Cancer science, 103(3), 504-509.
How It Works
Audeh, M. W., Carmichael, J., Penson, R. T., Friedlander, M., Powell, B., Bell-McGuinn, K. M., & Tutt, A. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. The Lancet, 376(9737), 245-251.
Guo, X. X., Wu, H. L., Shi, H. Y., Su, L., & Zhang, X. (2024). The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials. Cancer Management and Research, 2553-2562.
Tutt, A., Robson, M., Garber, J. E., Domchek, S. M., Audeh, M. W., Weitzel, J. N. & Carmichael, J. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. The Lancet, 376(9737), 235-244.
van der Noll, R., Jager, A., Ang, J. E., Marchetti, S., Mergui-Roelvink, M. W., de Bono, J. S., & Schellens, J. H. (2020). Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2). Investigational New Drugs, 38(4), 1096-1107.
Yamamoto, N., Nokihara, H., Yamada, Y., Goto, Y., Tanioka, M., Shibata, T.,& Tamura, T. (2020). A Phase I, dose‐finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors. Cancer science, 103(3), 504-509.
Safety Advice

Alcohol
consult your doctor

Pregnancy
consult your doctor

Breast Feeding
consult your doctor

Driving
unsafe

Kidney
safe if prescribed

Liver
safe if prescribed
Missed Doses
Quick Tips
FAQs
Bdparp 100 mg tablet is used for the treatment of breast, ovarian, prostate, and pancreatic cancer.
Bdparp 100mg tablet works by blocking the repair mechanism of DNA; as a result, the growth of cancer cells stops. The tablet inhibits PARP (poly-ADP-ribose polymerases), which belongs to the family of proteins that play an important role in genomic stability, DNA repair, and cellular stress responses. The enzymes repair the single-strand DNA breaks (SSBs). Bdparp 100 mg tablet inhibits the working of PARP enzymes, which hinders the growth and development of cancer cells.
A person with low white blood cells is advised to consult the doctor first before taking the Bdparp 100 mg tablet, as this drug can also cause neutropenia.
As soon as you remember, take the missed dose unless it's time for your next dose. You should never take a double dose to make up for a missed one.
Common side effects of the Bdparp 100 mg tablet are constipation, muscle pain, swelling, nausea, diarrhea, infection, loss of appetite, hair loss, vomiting, and weakness.
The doctor decides how long the treatment with the Bdparp 100 mg tablet will continue, depending on the stage and health of the patient
It is advised not to take alcohol while taking the Bdparp 100mg tablet, because consuming alcohol can cause serious side effects and can damage your liver badly. Consult your doctor if you have concerns or queries.
During pregnancy, it is not safe to take Bdparp 100 mg tablets, as they can cause harm to the unborn baby. Furthermore, during breastfeeding, this medicine must not be used. Please make sure to consult your healthcare provider regarding the same.
Reference
Audeh, M. W., Carmichael, J., Penson, R. T., Friedlander, M., Powell, B., Bell-McGuinn, K. M., & Tutt, A. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. The Lancet, 376(9737), 245-251.
Guo, X. X., Wu, H. L., Shi, H. Y., Su, L., & Zhang, X. (2024). The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials. Cancer Management and Research, 2553-2562.
Tutt, A., Robson, M., Garber, J. E., Domchek, S. M., Audeh, M. W., Weitzel, J. N. & Carmichael, J. (2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. The Lancet, 376(9737), 235-244.
van der Noll, R., Jager, A., Ang, J. E., Marchetti, S., Mergui-Roelvink, M. W., de Bono, J. S., & Schellens, J. H. (2020). Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2). Investigational New Drugs, 38(4), 1096-1107.
Yamamoto, N., Nokihara, H., Yamada, Y., Goto, Y., Tanioka, M., Shibata, T.,& Tamura, T. (2020). A Phase I, dose‐finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors. Cancer science, 103(3), 504-509.
Ratings And Reviews
4.33/5
3 Ratings
5 Star
33.33%
4 Star
66.67%
3 Star
0.00%
2 Star
0.00%
1 Star
0.00%
Isabella Martinez
Good quality for the price
9 months ago
Riya Shah
Perfect for my needs
9 months ago
View All Reviews
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MARKETER DETAILS
bdr pharma
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