SOFOSBUVIR AND DACLATASVIR 60/400MG (HEPCINAT PLUS)

Side effects  Hepcinat plus

This medicine may cause some mild or severe side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment. 

Common side effects  

• Nausea  

• Headache  

• Fatigue  

• Fever  

• Pale skin  

• Chest pain  

• Dizziness  

• Insomnia  

• Anemia  

• Diarrhea  

• Rash  

• Shortness of breath  

• Irregular heartbeat  

• Muscle pain  

• Loss of appetite  

• Allergic reaction  

• Back pain  

• Cramps  

• Mouth ulcers  

• Trouble sleeping  

• Loss of strength  

• Unusual tiredness  

• Sores  

• Chills  

• Unusual weakness  

• Itching  

• Blurred vision  

Note- immediate medical attention is required if any side effect occurs 

Dosage  of Hepcinat plus

Take this medicine as prescribed by your doctor. Do not skip or miss your dosing schedule. This medicine can be taken with or without food.  

Missed dose  

•  It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately.  

Overdose  

• In case of an overdose, the doctor will provide emergency medical treatment.

Warnings of Hepcinat plus

Before starting treatment with this medication, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.  

 Contraception  

• Use effective methods of contraception to prevent pregnancy while taking this medicine.  

Children and adolescents  

• This medicine is not advisable for use in children and adolescents. 

Warnings for female  

Pregnancy 

• Do not use this medicine if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.  

Breastfeeding 

• This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication. 

Precautions of Hepcinat plus

• Regular monitoring of liver function and the amount of hepatitis C virus (HCV) in your body is required.  

• Do not skip the regular dosing schedule  

• Inform your doctor if you experience any side effects like nausea, fatigue, headache, anemia, and rashes.  

• Do not stop taking this medicine without your doctor’s advice.   

• Contact your doctor if you have complications in the liver other than HCV infection.  

Cautions of Hepcinat plus

• Do not drive or operate heavy machinery.  

• Not safe for pregnant women.  

• Do not breastfeed while receiving this medication.  

• Do not crush or break the tablet.  

Q1. What is Hepcinat plus (Sofosbuvir and Daclatasvir)?  

Ans. This medicine is used in the treatment of the Hepatitis C virus (HCV). It works by removing the virus from the blood over a period of time.  

Q2. How does this medication work?  

Ans. This medication works by preventing the action of a specific protein that the virus needs to reproduce. It reduces the amount of HCV in the body and helps our immune system to fight against infection. 

Q3. What are the side effects?  

Ans. Some common side effects are:- nausea, fatigue, headache, anemia, rashes, muscle pain, insomnia, dizziness, blurred vision, etc.  

Q4. In what strength is it available?  

Ans. It is available in the strength of 60mg/400mg (Sofosbuvir 400mg + Daclatasvir 60mg).   

Q5. How to take this medicine?  

Ans. Take this medicine as prescribed by your doctor. Do not crush or break the tablet.  

Q6. What happens if I miss a dose?  

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q7. Can I take this medicine during breastfeeding?  

Ans. This medicine is not recommended in breastfeeding unless it is necessary. 

Q8. Does this medicine affect liver function?  

Ans. Please contact your doctor before consuming this drug. 

Q9. What should I avoid while receiving this medicine? 

Ans. Follow your doctor’s instructions about any restrictions on food and other activities.  

Q10. Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended for pregnant women.  

Q11. Can I drive after taking this medicine?  

Ans. This medicine may affect your vision. Do not drive if any symptoms occur.  

Q12. What are the storage conditions?  

Ans. Store this medicine at room temperature. Keep it away from heat and light.  

Q13. Can I consume alcohol while taking this medicine?  

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q14. What are the disadvantages of this medicine?  

Ans. There are certain disadvantages like:- shows a higher rate of side effects and dosage need to be modified.  

Interactions of Hepcinat plus 

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.  

Medicine interactions  

• Apalutamide  

• Carbamazepine  

• Enzalutamide  

• Primidone  

• St. john’s wort  

Alcohol interaction  

• Interaction with alcohol is unknown. Please consult your doctor before consuming this drug. 

Contraindications 

• Do not take this medicine if you are allergic to Sofosbuvir and Daclatasvir.  

• This medicine is not recommended in patients known to be hypersensitive. 

Reference

• Sofosbuvir and Daclatasvir: Drug information and uses are available at: https://www.webmd.com/drugs/2/drug-169287/daclatasvir-oral/details and https://www.drugs.com/cons/daclatasvir.html.

Sofosbuvir and Daclatasvir: Mechanism, Side Effects, and dosages available at: https://www.webmd.com/drugs/2/drug-169287/daclatasvir-oral/details and https://www.mayoclinic.org/drugs-supplements/daclatasvir-oral-route/precautions/drg-20151270?p=1