Marketed By
Hetero
Pack of
1 Injection
Salt Composition
Bendamustine
Storage
Keep in cold place
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Leuben 100mg Injection
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Overview
Bendamustine 100mg injection is used in the treatment of non-Hodgkin's Lymphoma. This medicine belongs to a group of cancer-fighting medications known as alkylating agents.
It works by killing cancerous cells and slowing down their growth. It is important to take a Leuben injection as prescribed by your doctor. Close monitoring of blood cell counts is required while having treatment with this medicine.
Indication
Multiple myeloma
Description
Bendamustine is a bifunctional mechlorethamine derivative. Mechlorethamine and its derivatives form electrophilic alkyl groups. These groups form covalent bonds with electron-rich nucleophilic moieties, resulting in interstrand DNA crosslinks. The bifunctional covalent linkage can lead to cell death via several pathways.
Side Effects
Bendamustine 100mg injection may cause some serious and common side effects. In case these side effects become worse, consult your doctor immediately.
How To Use
- Leuben 100mg is available in injection form and is advised to be taken as per the doctor's prescription. It can be given into a vein (intravenously) into a muscle (intramuscularly) by a doctor or nurse under strict medical supervision.
- Taking this injection in the wrong way may give you severe side effects. In case of overdose, contact your healthcare provider or doctor and they will provide you with medical attention.
- Missing or overdosing will impact the overall health of the patients and may also have side effects. So, it is always advisable to follow the prescription of the doctor strictly.
How It Works
- Leuben 100mg Injection is an anticancer medicine with Bendamustine as an active ingredient. It is an alkylating agent that works by destroying genetic material like DNA or RNA of the cancer cells to prevents the replication of rapidly growing cancer cells.
- Carboplatin causes the DNA strands to cross-link, that stops the cells from dividing and ultimately leads to their death. As it can cause some adverse impact on the body because it affects both healthy & cancerous cells.
Safety Advice
Alcohol
UNSAFE
Pregnancy
CONSULT YOUR DOCTOR
Breast Feeding
CONSULT YOUR DOCTOR
Driving
DANGER
Kidney
CAUTION
Liver
CAUTION
Missed Doses
It is advisable not to miss any dose. In case you miss a dose of Bendamustine 100mg injection consult your doctor soon.
Missing the dose will impact the overall health of the patients. So, it is always advisable to follow the prescription of the doctor strictly.
FAQs
This injection is used in the treatment of non-Hodgkin's Lymphoma. It interferes with the growth of cancerous cells and destroys them.
It works by damaging the DNA and RNA of cancer cells and slowing down their growth.
Some common side effects of Bendamustine injection are low blood platelets, pale skin, fever, bleeding gums, swollen glands, dizziness, etc.
It is advised not to drive after taking this medicine as this medicine may affect your vision and your ability to concentrate.
It is given as an infusion into the vein. Do not self-administer this medicine.
References
- Chang, J. E., & Kahl, B. S. (2012). Bendamustine for treatment of chronic lymphocytic leukemia. Expert opinion on pharmacotherapy, 13(10), 1495-1505. https://www.tandfonline.com/doi/abs/10.1517/14656566.2012.693163
- Corazzelli, G., Angrilli, F., D'Arco, A., Ferrara, F., Musto, P., Guarini, A., ... & Pinto, A. (2013). Efficacy and safety of bendamustine for the treatment of patients with recurring H odgkin lymphoma. British journal of haematology, 160(2), 207-215. https://onlinelibrary.wiley.com/doi/abs/10.1111/bjh.12120
- Kalaycio, M. (2008). Clinical experience with Bendamustine: A new treatment for patients with chronic lymphocytic leukemia. Clinical Leukemia, 2(4), 223-229. https://www.sciencedirect.com/science/article/pii/S1931692513600352
- Shotton, R., Broadbent, R., Alchawaf, A., Mohamed, M. B., Gibb, A., Martinez-Calle, N., ... & Linton, K. M. (2024). Safety of bendamustine for the treatment of indolent non-Hodgkin lymphoma: a UK real-world experience. Blood Advances, 8(4), 878-888. https://pubmed.ncbi.nlm.nih.gov/37967358/
- Tageja, N., & Nagi, J. (2010). Bendamustine: something old, something new. Cancer chemotherapy and pharmacology, 66(3), 413-423. https://pubmed.ncbi.nlm.nih.gov/20376452/
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The contents of this website are for informative purposes only. They are not deliberated to be an alternative to any professional medical prescription and treatment. Seek the advice of a qualified health provider for questions regarding the medical condition. Do not ignore any professional medical advice because of something you have read on this website. This website offers links to other websites, thereby enabling you to go to the other website directly. Therefore, Magicine Pharma isn't responsible for the content of the links in the website or links in the linked websites. The links are provided to assist the visitors and are not approved by any professional health provider.








