Resof-l
Prescription Required
Marketed By
dr.reddy
Pack of
28 tablet
Salt Composition
Sofosbuvir and Ledipasvir
Storage
Keep in cold place
₹25061.34₹27500
8.87% Off
Inclusive of all taxes
1

Resof-l
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Overview
Resof-L Tablet is an antiviral medication, which is used in combination with other medicines. It is used in the treatment of chronic hepatitis C virus (HCV) infection. It stops or prevents the growth of viruses in the body and helps remove the virus from the blood. Resof-L Tablet helps you to recover faster and control the infection from spreading in your body. This is a prescription-based medicine, which is to be taken only when prescribed by your doctor.
Indication
Hepatitis C
Uses
Treatment of Chronic hepatitis C virus (HCV) infection
Side Effects
The human body reacts differently to Resof-L Tablet. Response or undesired symptoms vary from individual to individual. Usually, they disappear with time as the body adjusts to the medicine; these side effects don't need special medical attention. Whereas if the symptoms don't disappear with time or you have severe side effects, then consult your doctor immediately. Some of the common side effects of Resof-L Tablet are mentioned below:
Headache
Fever
Chills
Nausea
Insomnia (difficulty in sleeping)
Tiredness
Loss of appetite
Fatigue Anemia (low number of red blood cells)
Skin rash
How To Use
Take the dose of Resof-L Tablet as per your healthcare provider’s prescription. Do not stop taking the medicine suddenly, unless your doctor tells you. This medicine is given under the strict supervision of a doctor. Do not self-administer. Overdose is a very unusual state for this medicine because it is given under the supervision of a healthcare provider. Resof-L Tablet can be taken without food or with food. The doctor will provide emergency medical treatment. You should not break, crush, or chew the medicine; it should be swallowed as a whole. It is advised to eat a healthy diet and drink plenty of fluids to overcome and prevent the side effects that have occurred after taking Resof-L Tablet.
How It Works
Resof-L Tablet is an antiviral medicine made up of Sofosbuvir and Ledipasvir. Both ingredients present in the medicine prevent the virus from multiplying. Thus, the viral count in the blood gets lowered, and the infection can be eliminated from the body. This medication is suitable for use in both adults and children aged three years and above. Resof-L Tablet inhibits an important Nonstructural protein 5A (NS5A) and viral phosphoprotein, which are involved in replication of the virus, assembly, secretion, and RNA viral production.
Safety Advice

Alcohol
unsafe
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Resof-L Tablet. Consult your doctor for further information.

Pregnancy
consult your doctor
Resof-L Tablet may be considered unsafe during pregnancy. Please consult your doctor in such a condition. According to some research data, taking Resof-L Tablet during pregnancy has shown harmful effects on the developing baby.

Breast Feeding
consult your doctor
Resof-L Tablet is probably not safe if you're breastfeeding. Kindly consult your doctor before taking Resof-L Tablet while breastfeeding, as there are chances that it may pass to the developing baby through the breast milk of the mother.

Driving
danger
It is advisable not to drive or operate heavy machinery after taking Resof-L Tablet, as you may feel dizzy.

Kidney
precaution
Share your medical history with your healthcare expert in case of kidney disease before taking Resof-L Tablet. Patients with renal impairment must be careful while taking Resof-L Tablet. They may require adjustment in the dose.

Liver
precaution
Inform your doctor before starting Resof-L Tablet if you have liver disease to avoid any serious side effects. Patients with hepatic impairment must be careful while taking Resof-L Tablet. They may require adjustment in the dose.
FAQs
Resof-L Tablet is an antiviral medication, used along with other medications, in the treatment of chronic Hepatitis C Virus (HCV) infection in adults.
Take the Resof-L Tablet exactly as your healthcare provider tells you. Do not alter the dose strength on your own. Do not crush, chew, or break the tablet.
Side effects of Resof-L Tablet are fever, nausea, anemia, insomnia, chills, muscle pain, cramps, fainting, and skin rash. If you experience these or any other side effects, make sure to consult your healthcare provider for the same.
Avoid the consumption of fatty or sugary foods and alcohol.
Do not drive or operate heavy machines if you feel unwell after taking this medicine.
If you miss a dose of Resof-L Tablet, take it as soon as you remember. Do take an extra dose of the medicine to make up for the missed one.
It is important to complete the full course of the Resof-L Tablet as prescribed by the doctor. If you feel better, then you should also not stop taking Resof-L Tablet, as it may worsen your symptoms.
Time may vary from individual to individual, depending on the severity and stage of the disease. But it is essential to complete the full course of the Resof-L Tablet.
Consult your doctor before taking any supplements or vitamins to prevent any kind of interactions with Resof-L Tablet, which can cause severe effects to the individual.
No, Resof-L Tablet is not a habit-forming medicine.
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Reference
Abergel A, Asselah T, Metivier S, Kersey K, Jiang D, Mo H, Pang PS, Samuel D, Loustaud-Ratti V. (2023). Ledipasvir-sofosbuvir in patients with hepatitis C virus genotype 5 infection: an open-label, multicentre, single-arm, phase 2 study. Lancet Infect Dis. 16(4):459-64.
Duc N. T, Vittorio F, Alexander Z, Venkat R. G, Akihiro H, Mingjun H, Jason A. W. (2025). The Discovery and Chemical Development of Odalasvir, a Potent and Selective HCV NS5A Inhibitor, Complete Accounts of Integrated Drug Discovery and Development: Recent Examples from the Pharmaceutical Industry Volume 5, 1-58.
Lele Z, Matthew H, Prahalad G, Mahan G, Steven K, Haiting C, Paul K, Eleanor B, M. Azim A, Katrina L, Genetically distinct within-host subpopulations of hepatitis C virus persist after Direct-Acting Antiviral treatment failure, PLOS Pathogens, 21, 4, (e1012959).
Nambaru Vidya Sagar, Anamika Goyal, Abhishek Raj, Subhash Chandra, Upendra Nath Gupta, Prabhat Agrawal, Rajat Gupta, Rahul Agrahari. (2024). SVR timelines in hepatitis irrespective of viral genotype: An Indian perspective, Journal of Family Medicine and Primary Care, 14, 4, 1425-1430.
Preferred Therapy for Specific Viral Pathogens, Nelson’s Pediatric Antimicrobial Therapy, (2025).
Thomas R. O, David J. W, Varun S, Kerry G.M., Sabrina C, Francine S.B., Ludmila P. O, Ruth M. P, Jennifer B. L. (2024). IFNL4 genotype and other personal characteristics to predict response to 8-week sofosbuvir-based treatment for chronic hepatitis C, Journal of Infection, 89, 5, (106258).
Yong P, Sitthichai K, Nungruthai S, Pornjarim N, Ritthideach Y, Wijittra P, Napaporn P, Chatree J. (2025). Microelimination of Hepatitis C in Thailand, Phetchabun Model: Progress, Challenges, and Future Directions, Journal of Clinical Medicine, 14, 11, 3946.
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