Sofovir 400mg Tablet

Prescription Required

Manufactured By

Hetero Healthcare Ltd

Pack of

28 tablet

Salt Composition

Sofosbuvir 400mg

Storage

Keep in cold place

shipping-zone

Delivering To:

All Substitutes

Overview

Sofosbuvir 400mg tablet is used with other medications in the treatment of chronic (long-lasting) hepatitis C virus (HCV) infection in adults. It is an antiviral medicine that lowers the amount of virus in the body and works to eliminate the virus over some time.

Indication

Hepatitis C

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Description

Sofosbuvir tends to inhibit the Hepatitis C NS5B protein. It shows a high barrier to the development of resistance. Sofosbuvir is a prodrug of the Protide type, wherein the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203, which is followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), with repeated phosphorylation. Dephosphorylation tends to create the inactive metabolite GS-331077. The half-life of Sofosbuvir is 0.4 hours, and the half-life of GS-331077 is 27 hours. Following a single 400 mg oral dose of Sofosbuvir, 80% is normally excreted in the urine, 2.5% in expired air recovery, and 14% in feces.

Side Effects

Sofosbuvir 400mg tablet may cause some serious and unwanted side effects that require immediate medical attention otherwise it can also lead to higher risk. Do not forget to discuss the risks and benefits of this medication with your doctor.

Insomnia

Nausea

Fainting 

Neutropenia (low white blood cell count)

Chills

Fatigue

Headache 

Loss of appetite

Weakness

Skin rash

Itching

Irritability 

Joint pain

Fever

How To Use

Do not crush, chew, or break the tablet. Take the same dose as prescribed by your healthcare provider.

Please seek emergency medical attention in case of overdose.

Safety Advice

Alcohol

Alcohol

unsafe

It is advisable not to consume alcohol while taking this medicine.

Pregnancy

Pregnancy

consult your doctor

Do not take ​Sofosbuvir 400mg tablet without consulting the doctor, in case of pregnancy.

Breast Feeding

Breast Feeding

consult your doctor

Without a doctor's consultation, do not take this medicine if you're breastfeeding.

Driving

Driving

danger

It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.

Kidney

Kidney

caution

Do not take ​Sofosbuvir 400mg tablet without a doctor's consultation in case of kidney problems.

Liver

Liver

caution

Share your medical history with the doctor in case of liver disease before taking this medicine.

Missed Doses

In case of a missed dose, take the medicine as soon as you remember. However, if it is already time for the next dose, do not take the previous dose. Skip it and take the scheduled dose. Also, tell your healthcare provider about the same.

FAQs

What is the use of ​Sofosbuvir 400mg tablet?

Sofosbuvir tablet is an antiviral medicine. It is used with other medicines to treat chronic (long-lasting) hepatitis C virus (HCV) infection in adults.

How should I take a Sofovir tablet?

Do not crush, chew, or break the tablet. Take it exactly as your healthcare provider tells you. 

What are the storage conditions for Sofovir tablets?

Store at room temperature (10-30°C). Keep it covered, and away from children, direct light, heat, and moisture. 

What are the possible side effects of Sofosbuvir 400mg Tablet?

There can be some side effects of Sofovir such as fever, headache, irritability, anemia, fatigue, and diarrhea. Nausea and skin rash. Kindly consult your healthcare provider if you experience these or any other side effects.

Can I drive after taking this medicine?

Do not drive or operate heavy machines in case you feel unwell after taking this medicine.

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MARKETER DETAILS

Hetero Healthcare Ltd