Mfd. by :- Zydus Cadila (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand name: Exemptia
Generic name: Adalimumab
Strength: 40mg/0.8ml
Manufacturer: Zydus Cadila
Dosage form: Injection
Indication: Rheumatoid arthritis
Storage: Store in a refrigerator
Exemptia (Adalimumab) is available in the form of an injection and a strength of 40mg/0.8 ml. This injection is used for the treatment of various conditions (rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease, and ulcerative colitis). Adalimumab 40mg Injection works by blocking the action of chemical messengers, which are responsible for certain joint diseases. Before starting treatment, inform your physician if you have a history of heart, liver, and kidney disease. Do not self-administer Exemptia medication.
Adalimumab 40mg Injection decreases the levels of acute-phase reactant proteins of inflammation (C reactive protein [CRP] and erythrocyte sedimentation rate [ESR]) and serum cytokines (IL-6) and it was compared to baseline in patients diagnosed with rheumatoid arthritis. In patients diagnosed with Crohn’s disease, a decreased level of CRP was also observed in them. Serum levels of matrix metalloproteinases (MMP-1 and MMP-3) that lead to the tissue remodeling responsible for cartilage destruction were also found to be decreased after administering adalimumab in patients, reduction in signs and symptoms of disease, the induction of clinical response, and inhibition of structural damage, and improvements in physical function in adult and pediatric patients with various inflammatory conditions have been demonstrated.
Adalimumab 40mg injection belongs to a class of medications known as biological response modifiers. This injection helps in relieving symptoms like swelling, pain, and redness which are caused by various disorders (rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis, uveitis, chronic plaque psoriasis, etc.). The use of Adalimumab 40mg injection may result in the formation of autoantibodies in some patients, immediate discontinuation of treatment is recommended on such patients.
Following are the possible side effects that can occur during your treatment with Adalimumab 40mg injection. Contact your healthcare provider if they last longer.
Note - contact your medical practitioner immediately if any of the above-mentioned side effects occur.
Adalimumab 40mg injection should be administered by a qualified nurse or medical professional and recommended dosage is decided by your physician according to your medical history and current health conditions.
If you miss a scheduled dose of Adalimumab injection, contact your health professional as soon as possible. Try not to miss or skip your dosage of Exemptia injection.
In case of an overdose of Exemptia (Adalimumab), contact your medical practitioner immediately in order to avoid severe side effects.
Before starting treatment with Exemptia (Adalimumab 40mg) injection, check all the possible risks and benefits with your healthcare provider. Use of Exemptia injection may cause severe allergic reactions in some patients.
· Pregnancy
o Exemptia (Adalimumab 40mg) injection is not recommended for use in pregnant women because it may affect the unborn baby.
· Breastfeeding
o Do not use Exemptia (Adalimumab 40mg) injection in breastfeeding. Talk to your healthcare provider before starting treatment with Exemptia.
· Use of Exemptia (Adalimumab 40mg) injection may affect your immune system, avoid contact with people who have infections.
· Caution is recommended in patients who have pre-existing nervous system disorders like multiple sclerosis and optic neuritis.
· Close monitoring of hematological function is required during treatment with Exemptia injection.
· Discontinue the use of Exemptia (Adalimumab) if severe allergic reactions occur.
· Exemptia injection may increase the risk of reactivation of hepatitis b virus in some patients
· Exemptia medication may result in the formation of autoantibodies in some patients, immediate discontinuation of treatment is recommended in such conditions.
· Do not self-administer Exemptia (Adalimumab 40mg Injection)
· Do not drive or operate heavy machinery
· Do not skip a dose
· Do not overdose
Ans. Adalimumab 40mg injection is used for the treatment of various conditions (rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease, ulcerative colitis).
Ans. Use Adalimumab 40mg injection as prescribed by your healthcare provider and it should be administered under the supervision of a healthcare professional.
Ans. Some common side effects of Adalimumab 40mg injection are nausea, weakness, pale skin, irregular heartbeat, difficulty in breathing, vomiting, fever, etc.
Ans. It is advisable to consult your medical practitioner in case of an overdose of Exemptia injection.
Ans. Use of Exemptia injection is not recommended for use in pregnancy.
Ans. Consult your health professional and discuss the risk and benefits of Exemptia injection.
Ans. It is not advisable to drive after taking Exemptia because it can cause side effects like blurred vision and dizziness.
Ans. Exemptia injection is available in the strength of 40mg/0.8ml
Ans. Consult it with your medical practitioner, before starting treatment with Exemptia injection.
Adalimumab 40mg injection may interact with other medications and it can cause some unusual side effects. Do not forget to discuss it with your healthcare provider.
There may be an interaction between Adalimumab 40mg injection and the medicines mentioned below
· Budesonide
· Azathioprine
· Cisplatin
· Betamethasone
· Clozapine
· Linezolid
· Tacrolimus
· Hydrocortisone
· Cyclosporine
· Triamcinolone
· Altretamine
The following are the disease interactions that may occur with the Adalimumab 40mg injection
· Malignancies
· Congestive heart failure
· Neurological disorders
· Hepatitis B
· Infections
· Tuberculosis
Avoid consuming alcohol while receiving treatment with Adalimumab 40mg injection because it may cause some side effects like dizziness.
Use of Adalimumab 40mg injection is not recommended in patients who are allergic to Adalimumab r any other inactive ingredients.
Do not use Exemptia (Adalimumab) injection if you have a pre-existing problem of hypersensitivity.
Reference
Adalimumab: Mechanism, side effects, and dosage are available at: https://my.clevelandclinic.org/health/drugs/18813-adalimumab-injection, https://www.webmd.com/drugs/2/drug-64712/adalimumab-subcutaneous/details, and https://medlineplus.gov/druginfo/meds/a603010.html.
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